Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) ELISA Kits

LGALS8 encodes a member of the galectin family. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 8 Antibodies (124) and Lectin, Galactoside-Binding, Soluble, 8 Proteins (29) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LGALS8 56048 Q9JL15
LGALS8 3964 O00214
LGALS8 116641  
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Top Lectin, Galactoside-Binding, Soluble, 8 ELISA Kits at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Cow 0.118 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$795.79
Details
Mouse 0.055 ng/mL 0.156 ng/mL - 10 ng/mL 96 Tests Log in to see 15 to 17 Days
$852.24
Details
Rat 0.028 ng/mL 0.156 ng/mL - 10 ng/mL 96 Tests Log in to see 15 to 17 Days
$891.06
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for Lectin, Galactoside-Binding, Soluble, 8 Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) interaction partners

  1. these findings identify gal-8 as a new physiologic player in the regulation of bone mass.

  2. Galectin-8 regulates antibacterial autophagy through differential recognition of host glycans on damaged phagosomes.

  3. Galectin-8 activates dendritic cells and stimulates antigen-specific immune response elicitation.

  4. these data suggest that Gal-8 promotes the differentiation of highly suppressive Treg cells, which has implications for the treatment of inflammatory and autoimmune diseases.

  5. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C, podoplanin and integrin pathways plays a key role.

  6. Gal-8mut was unable to induce T-cell proliferation, but efficiently co-stimulated antigen-specific responses, bothin vitroandin vivo.

  7. Gal-8 emerges as an attractive therapeutic candidate.

  8. Galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice.

  9. Gal-8 stimulated naive T cells, but had an antiproliferative effect when these cells were activated.A dose of recombinant Gal-8 administered with a suboptimal Ag dose to DO11.10 mice strengthened weak responses in vivo.

  10. a novel role for Gal-8 in collaboration with Gal-1 in plasma cell formation, and suggest the possibility of using distinct LacNAc ligands to modulate the function of Gals.

  11. The findings of the present study delineate the differential molecular requirements for Gal-8 activities on T-cells, and suggest a dual activity relying on activation state.

  12. galectin-8 is expressed in the thymus in mouse, which suggests an active role for this lectin in shaping the mature T cell repertoire

  13. Taken together, our findings support a distinctive role for locally produced Gal-8 as an enhancer of otherwise borderline immune responses and also suggest that Gal-8 might fuel the reactivity at inflammatory foci.

Human Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) interaction partners

  1. analysis of crystallographic structures of the galectin-8 N-terminal domain (galectin-8N) in complex with LNT and LNnT

  2. Gal-8 served as a new positive prognostic factor for the OS and DFS of ovarian cancer patients.

  3. We further demonstrated using the NMR-based hydrogen-deuterium exchange (HDX) that lactose binding increases the exchange rates of residues located on the opposite side of the ligand-binding pocket for hGal1 and hGal8(NTD), indicative of allostery. Additionally, lactose binding induces significant stabilisation of hGal8(CTD) across the entire domain

  4. findings reveal that differential levels of Gal-3 and Gal-8 expression and recruitment to Group A streptococcus (GAS) between epithelial cells and endothelial cells may contribute to the different outcomes of GAS elimination or survival and growth of GAS in these two types of cells.

  5. the natural and conserved expression of Gal-8 in tumour cells is responsible for the metastatic evolution of prostate cancer.

  6. Both Gal-8 isoforms led to enhanced adhesion of myeloma cells to vascular endothelium under dynamic shear stress conditions, Gal-8L (by more than 40-fold) even stronger than Gal-8S.

  7. Our data indicate that Gal-8 interacts with ALCAM at the surface of breast cancer cells through glycosylation-dependent mechanisms. A novel heterophilic interaction between ALCAM and Gal-8 is demonstrated here, suggesting its physiologic relevance in the biology of breast cancer cells

  8. we detected Gal-8 in human cerebrospinal fluid, suggesting a role in the CNS immune-surveillance circuit. In addition, we show that MS patients generate function-blocking anti-Gal-8 antibodies with pathogenic potential. Furthermore, circulating anti-Gal-8 antibodies associate with relapsing-remitting MS, and not with progressive MS phenotypes, predicting clinical disability at diagnosis within the first year of follow-up

  9. Data suggest that galectin-8 is a potential independent favorable prognostic biomarker for survival and recurrence of patients with gastric cancer after surgery.

  10. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C, podoplanin and integrin pathways plays a key role.

  11. Platelet-derived factor V/Va is generated following endocytosis of the plasma-derived molecule by the platelet precursor cells, megakaryocytes, via a two receptor system consisting of LRP-1 and an unidentified specific "binding site".

  12. Gal-8 expression is a potential independent unfavorable prognostic indicator for postoperative recurrence of patients with localized pT1 clear cell renal cell carcinoma

  13. The fundamental roles of galectin-8 in human anaplastic large cell lymphoma

  14. The implications of gal-8 in tumor angiogenesis remain to be further explored, but it is exciting to speculate that modulating gal-8-glycan interactions could be used to block lymphatic-vascular connections vital for metastasis

  15. We integrate here the available information on Gal-8 expression in different tumor types and attempt to elucidate associations of its expression and localization with tumor progression[review]

  16. these results not only confirm the pro-inflammatory role we have already proposed for Gal-8 in other cellular systems but also suggest that this lectin is orchestrating the interaction between leukocytes, platelets and endothelial cells

  17. Whereas Galectin (Gal)-1, -3, and -8 triggered vascular endothelial growth factor (VEGF) release, only Gal-8 induced endostatin secretion.

  18. Focusing on the F19Y change in galectin-8, we study of consequences of a single-site substitution in the carbohydrate recognition domain of this family of cellular effectors.

  19. analysis of how human Galectin-8C domain interacts with its glycan ligands

  20. Data indicate that the binding site in galectin-8 is essential for the recruitment of the autophagy receptor NDP52 to cytosol-exposed Salmonella Typhimurium.

Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Antigen Profile

Antigen Summary

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with LGALS8

  • galectin 8 (LGALS8) antibody
  • lectin, galactose binding, soluble 8 (Lgals8) antibody
  • galectin 8 (Lgals8) antibody
  • lectin, galactoside binding soluble 8 S homeolog (lgals8.S) antibody
  • 1200015E08Rik antibody
  • AI326142 antibody
  • D13Ertd524e antibody
  • Gal-8 antibody
  • galectin-8 antibody
  • Lgals-8 antibody
  • LGALS8 antibody
  • PCTA-1 antibody
  • PCTA1 antibody
  • Po66-CBP antibody
  • xgalectin-VIIIa antibody

Protein level used designations for LGALS8

lectin, galactoside-binding, soluble, 8 , lectin, galactoside-binding, soluble, 8 (galectin 8) , galectin-8-like , gal-8 , galectin 8 , galectin-8 , galectin-8L , lectin, galactose binding, soluble 5 , galectin-8 variant II , Po66 carbohydrate binding protein , galectin-8g , po66 carbohydrate-binding protein , prostate carcinoma tumor antigen 1 , 30 kDa S-type lectin , RL-30 , lectin, galactose binding, soluble 8 , galectin family xgalectin-VIIIa , xgalectin-VIII

GENE ID SPECIES
710375 Macaca mulatta
743841 Pan troglodytes
100436942 Pongo abelii
100595058 Nomascus leucogenys
56048 Mus musculus
430948 Gallus gallus
3964 Homo sapiens
479193 Canis lupus familiaris
100156193 Sus scrofa
506977 Bos taurus
116641 Rattus norvegicus
100343919 Oryctolagus cuniculus
100733991 Cavia porcellus
101115850 Ovis aries
398442 Xenopus laevis
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