Leucine-Zipper-Like Transcription Regulator 1 (LZTR1) ELISA Kits

LZTR1 encodes a member of the BTB-kelch superfamily. Additionally we are shipping LZTR1 Antibodies (33) and LZTR1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LZTR1 8216 Q8N653
Anti-Rat LZTR1 LZTR1 360745  
LZTR1 66863 Q9CQ33
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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

More ELISA Kits for LZTR1 Interaction Partners

Human Leucine-Zipper-Like Transcription Regulator 1 (LZTR1) interaction partners

  1. We report here two families in which segregate both multiple schwannomas and glioblastoma. In the first family, the proband received a diagnosis with of schwannomatosis after a surgery for a lumbar schwannoma at age 43, molecularly confirmed by identification of a germline heterozygous mutation in LZTR1.

  2. Pathogenic mutations affecting either RIT1 or LZTR1 resulted in incomplete degradation of RIT1.

  3. These clinical and genetic data confirm the existence of a form of Noonan syndrome that is inherited in an autosomal recessive pattern and identify biallelic mutations in LZTR1.

  4. RAS regulation by LZTR1-mediated ubiquitination provides an explanation for the role of LZTR1 in human disease.

  5. LZTR1 acts as a conserved regulator of RAS ubiquitination and MAPK pathway activation. Because LZTR1 disease mutations failed to revert loss-of-function phenotypes, these findings provide a molecular rationale for LZTR1 involvement in a variety of inherited and acquired human disorders.

  6. LZTR1 mutation is associated with Noonan syndrome.

  7. the malignancy risk in schwannomatosis is not well defined but may include an increased risk of malignant peripheral nerve sheath tumor in SMARCB1 Imaging protocols are also proposed for SMARCB1 and LZTR1 schwannomatosis and SMARCE1-related meningioma predisposition.

  8. Nerve lesions and LZTR1 germline mutations in segmental schwannomatosis.

  9. Data indicate that molecular analysis of leucine-zipper-like transcription regulator 1 (LZTR1) may contribute to the molecular characterization of schwannomatosis patients.

  10. We show for the first time that an inherited mutation in PBRM1 predisposes to RCC.

  11. Data confirm the relationship between mutations in LZTR1 and schwannomatosis. They indicate that germline mutations in LZTR1 confer an increased risk of vestibular schwannoma.

  12. Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas.

  13. LZTR-1 is the first BTB-kelch protein that exclusively localizes to the Golgi network

LZTR1 Antigen Profile

Antigen Summary

This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

Gene names and symbols associated with LZTR1

  • leucine-zipper-like transcriptional regulator 1 (LOC411262) antibody
  • leucine zipper like transcription regulator 1 (LZTR1) antibody
  • apoptosis inducing factor, mitochondria associated 3 (AIFM3) antibody
  • leucine-zipper-like transcription regulator 1 (lztr1) antibody
  • leucine zipper like transcription regulator 1 (lztr1) antibody
  • leucine-zipper-like transcription regulator 1 L homeolog (lztr1.L) antibody
  • leucine-zipper-like transcription regulator 1 (Lztr1) antibody
  • leucine-zipper-like transcriptional regulator, 1 (Lztr1) antibody
  • 1200003E21Rik antibody
  • AI591627 antibody
  • AW550890 antibody
  • BTBD29 antibody
  • DKFZp459B233 antibody
  • LZTR-1 antibody
  • LZTR1 antibody
  • si:dkey-98f17.2 antibody
  • wu:fj87c05 antibody
  • zgc:158250 antibody

Protein level used designations for LZTR1

leucine-zipper-like transcription regulator 1 , Leucine-zipper-like transcriptional regulator 1 , fj87c05 , leucine-zipper-like transcriptional regulator 1 , leucine-zipper-like regulator-1 , leucine-zipper-like transcriptional regulator, 1 , LZTR-1

411262 Apis mellifera
421166 Gallus gallus
458670 Pan troglodytes
696330 Macaca mulatta
100050778 Equus caballus
100158621 Xenopus (Silurana) tropicalis
100173934 Pongo abelii
100347953 Oryctolagus cuniculus
100557691 Anolis carolinensis
792832 Danio rerio
431916 Xenopus laevis
8216 Homo sapiens
608108 Canis lupus familiaris
506776 Bos taurus
360745 Rattus norvegicus
66863 Mus musculus
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