Ligand of Numb-Protein X 1 (LNX1) ELISA Kits

LNX1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. Additionally we are shipping LNX1 Antibodies (50) and LNX1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LNX1 16924 O70263
LNX1 84708 Q8TBB1
Anti-Rat LNX1 LNX1 360926  
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More ELISA Kits for LNX1 Interaction Partners

Zebrafish Ligand of Numb-Protein X 1 (LNX1) interaction partners

  1. Bozozok (Boz, also known as Dharma or Nieuwkoid) as a binding partner and substrate of Lnx-l.

Mouse (Murine) Ligand of Numb-Protein X 1 (LNX1) interaction partners

  1. These findings provide functional insights into the LNX protein family, particularly the neuronal LNX1p70 isoform.

  2. the PDZ domain-containing protein (show USH1C ELISA Kits) ligand-of-numb protein (show NUMBL ELISA Kits)-X (LNX) is found in complex with the coxsackievirus and adenovirus receptor (show CXADR ELISA Kits) (CAR)

  3. LNX1 may play a role in regulating (show ERBB2 ELISA Kits) neuregulin-1/ErbB signaling in perisynaptic Schwann cells.

  4. LNX1 provides an endocytic scaffold for JAM4 (show IGSF5 ELISA Kits) that is implicated in the reorganization of cell junctions.

Human Ligand of Numb-Protein X 1 (LNX1) interaction partners

  1. study provided the evidences that LNX1 signaling plays important roles in regulating the stemness of colon cancer cells

  2. LNX was closely related to human gliomas and suggested it plays an important role in gliomas by notch (show NOTCH1 ELISA Kits) signaling.

  3. LNX1-mediated ubiquitination and degradation of PBK (show PBK ELISA Kits) inhibited cell proliferation and enhanced sensitivity to doxorubicin-induced apoptosis.

  4. identify and confirm six novel LNX1 binding partners: KCNA4 (show KCNA4 ELISA Kits), PAK6 (show PAK6 ELISA Kits), PLEKHG5 (show PLEKHG5 ELISA Kits), PKC-alpha1, TYK2 (show TYK2 ELISA Kits) and PBK (show PBK ELISA Kits), and suggest that LNX1 functions as a signalling scaffold.

  5. The authors found a high level of LNX1 and LNX2 mRNAs in endocarditis, the principal manifestation of chronic Q fever, but not in acute Q fever.

  6. LNX1 and LNX2 interact with CD8alpha and promote its ubiquitylation and endocytosis

  7. Down-regulation of LNX could result in cell cycle arrest in G0/G1 phase through inhibition of beta-catenin (show CTNNB1 ELISA Kits), MAPK (show MAPK1 ELISA Kits), NFkappaB (show NFKB1 ELISA Kits), c-Myc (show MYC ELISA Kits)-dependent pathway and activation of p53 (show TP53 ELISA Kits), TGF-beta (show TGFB1 ELISA Kits)-dependent pathway.

  8. LNX and RhoC (show RHOC ELISA Kits) might be part of a larger protein complex that would have important functions in signaling transduction about regulating the transcriptional activities of AP-1 (show FOSB ELISA Kits).

  9. identifed ligand of Numb protein (show NUMBL ELISA Kits) X as an Np9-interacting partner; findings point to the possibility that Np9 affects tumorigenesis through the LNX/Numb (show NUMB ELISA Kits)/Notch (show NOTCH1 ELISA Kits) pathway

  10. The presence of multiple protein binding domains involved in signal transduction and interaction with Numb (show NUMB ELISA Kits) and SKIP suggested an important role for LNX in tumorogenesis.

LNX1 Antigen Profile

Antigen Summary

This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.

Gene names and symbols associated with LNX1

  • ligand of numb-protein X 1 (LNX1) antibody
  • ligand of numb-protein X 1 (lnx1) antibody
  • ligand of numb-protein X 1 (Lnx1) antibody
  • fj78f06 antibody
  • LNX antibody
  • LNX1 antibody
  • MPDZ antibody
  • PDZRN2 antibody
  • si:dkey-12h2.1 antibody
  • wu:fj78f06 antibody
  • zgc:152906 antibody

Protein level used designations for LNX1

ligand of numb-protein X 1 , multi-PDZ-domain-containing protein , E3 ubiquitin-protein ligase LNX , E3 ubiquitin-protein ligase LNX-like , e3 ubiquitin-protein ligase LNX-like , ligand of Numb protein X 1 , ligand of Numb-binding protein 1 , numb-binding protein 1 , PDZ domain-containing ring finger protein 2 , multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX

422752 Gallus gallus
461322 Pan troglodytes
561226 Danio rerio
697862 Macaca mulatta
100226096 Taeniopygia guttata
100385548 Callithrix jacchus
100474545 Ailuropoda melanoleuca
100487348 Xenopus (Silurana) tropicalis
100565507 Anolis carolinensis
100601961 Nomascus leucogenys
540694 Bos taurus
16924 Mus musculus
84708 Homo sapiens
475143 Canis lupus familiaris
360926 Rattus norvegicus
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