Lymphocyte Antigen 75 Proteins (LY75)

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity).

list all proteins Gene Name GeneID UniProt
Mouse LY75 LY75 17076 Q60767
Human LY75 LY75 4065 O60449
Rat LY75 LY75 499800  
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Top Lymphocyte Antigen 75 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
Human Cells Human His tag SDS-PAGE 100 μg Log in to see 20 to 21 Days
$437.80
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Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 Days
$581.90
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Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$720.00
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Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
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More Proteins for Lymphocyte Antigen 75 (LY75) Interaction Partners

Mouse (Murine) Lymphocyte Antigen 75 (LY75) interaction partners

  1. this study shows that CD205-TLR9 (show TLR9 Proteins)-IL-12 (show IL12A Proteins) axis contributes to CpG-induced oversensitive liver injury in Hepatitis B viral antigens transgenic mice by promoting the interaction of NKT (show CTSL1 Proteins) cells with Kupffer cells

  2. Antigen targeting to DEC-205 on dendritic cells leads to an IL-10 (show IL10 Proteins)-dependent downregulation of CXCR3 (show CXCR3 Proteins) expression on differentiated antigen-specific Th1 (show HAND1 Proteins) cells in vivo. This downregulation interferes with the migration of Th1 (show HAND1 Proteins) cells into the gut (show GUSB Proteins) and protects mice against severe acute and relapsing intestinal inflammation.

  3. DNA vaccines encoding DEC205-targeted antigens induce peripheral tolerance rather than immunity

  4. The DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8 (show CD8A Proteins) T cells independently of PD-1 (show PDCD1 Proteins) and PD-L1 (show CD274 Proteins).

  5. Through analysis of both polyclonal and monoclonal transgenic TCR T-cell development in the context of CD205 deficiency, we demonstrate that CD205 does not play an overt role in T cell development or selection.

  6. Introduction of a labile dipeptide linker at the N terminus of a T-cell epitope improves proteasome-dependent class I MHC-restricted peptide cross-presentation when delivered by alphaDEC205 in vitro and in vivo.

  7. Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.

  8. CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

  9. Langerin (show CD207 Proteins)-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 antibodies from the skin to the draining lymph nodes in steady state and inflammation.

  10. For production of cytotoxic T cells, DEC-205 and Clec9A (show CLEC9A Proteins), but not Clec12A (show CLEC12A Proteins), are effective targets for antibody-mediated delivery of antigens for vaccination, although only in the presence of adjuvants.

Human Lymphocyte Antigen 75 (LY75) interaction partners

  1. keratins are the cellular ligands of human DEC205.

  2. High LY75 expression is associated with metastasis of ovarian cancer.

  3. IL-6 (show IL6 Proteins), DEC205, and CD86 (show CD86 Proteins) can be predictive biomarkers for the respiratory and immune effects of ambient PM2.5.

  4. LY75 Gene Polymorphisms are Associated with Inflammatory Bowel Disease.

  5. results suggest that DEC205 is an immune receptor that recognizes apoptotic and necrotic cells specifically through a pH-dependent mechanism

  6. Variants in LY75 were associated with a Crohn's disease phenotype involving erythema nodosum.

  7. DEC-205 is a cell surface receptor for CpG olligonucleotides.

  8. Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.

  9. The most significantly associated SNPs to type 2 diabetes mellitus in this study are expression SNPs to the lymphocyte antigen 75 gene, the ubiquitin-specific peptidase 36 gene, and the phosphatidylinositol transfer protein (show PITPNA Proteins), cytoplasmic 1 gene.

  10. CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

Lymphocyte Antigen 75 (LY75) Protein Profile

Protein Summary

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.

Gene names and symbols associated with Lymphocyte Antigen 75 Proteins (LY75)

  • lymphocyte antigen 75 (LY75)
  • lymphocyte antigen 75 (Cyan7822_2917)
  • lymphocyte antigen 75 (LY5)
  • lymphocyte antigen 75 (ly75)
  • CD205 protein (cd205)
  • lymphocyte antigen 75 (LOC100380704)
  • CD302 antigen (LOC100433861)
  • lymphocyte antigen 75 (LOC100483541)
  • lymphocyte antigen 75 (Ly75)
  • CD205 protein
  • CLEC13B protein
  • DEC-205 protein
  • DEC205 protein
  • GP200-MR6 protein
  • im:7150926 protein
  • Ly-75 protein
  • LY75 protein
  • LYT75 protein
  • MGC140308 protein
  • RGD1565962 protein
  • si:dkey-78p20.2 protein

Protein level used designations for Lymphocyte Antigen 75 Proteins (LY75)

lymphocyte antigen 75 , DEC-205/CD205 protein , DEC-205/CD205 , CD205 protein , DEC-205 protein , Lymphocyte antigen 75 , lymphocyte antigen 75-like , ly-75 , C-type lectin domain family 13 member B

GENE ID SPECIES
407236 Bos taurus
9739406 Cyanothece sp. PCC 7822
100060284 Equus caballus
100500738 Oncorhynchus mykiss
100462946 Takifugu rubripes
424192 Gallus gallus
459682 Pan troglodytes
488366 Canis lupus familiaris
504036 Danio rerio
595126 Sus scrofa
100101125 Felis catus
100380704 Salmo salar
100433861 Pongo abelii
100483541 Ailuropoda melanoleuca
17076 Mus musculus
4065 Homo sapiens
499800 Rattus norvegicus
101830769 Mesocricetus auratus
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