Lymphocyte Antigen 75 Proteins (LY75)

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Additionally we are shipping Lymphocyte Antigen 75 Antibodies (222) and Lymphocyte Antigen 75 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LY75 17076 Q60767
LY75 4065 O60449
Rat LY75 LY75 499800  
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Top Lymphocyte Antigen 75 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Human Cells Human His tag SDS-PAGE 100 μg Log in to see 14 to 16 Days
$437.80
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 Days
$581.90
Details
Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
Details

LY75 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,

More Proteins for Lymphocyte Antigen 75 (LY75) Interaction Partners

Mouse (Murine) Lymphocyte Antigen 75 (LY75) interaction partners

  1. this study shows that CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in Hepatitis B viral antigens transgenic mice by promoting the interaction of NKT cells with Kupffer cells

  2. Antigen targeting to DEC-205 on dendritic cells leads to an IL-10-dependent downregulation of CXCR3 expression on differentiated antigen-specific Th1 cells in vivo. This downregulation interferes with the migration of Th1 cells into the gut and protects mice against severe acute and relapsing intestinal inflammation.

  3. DNA vaccines encoding DEC205-targeted antigens induce peripheral tolerance rather than immunity

  4. The DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8 T cells independently of PD-1 and PD-L1.

  5. Through analysis of both polyclonal and monoclonal transgenic TCR T-cell development in the context of CD205 deficiency, we demonstrate that CD205 does not play an overt role in T cell development or selection.

  6. Introduction of a labile dipeptide linker at the N terminus of a T-cell epitope improves proteasome-dependent class I MHC-restricted peptide cross-presentation when delivered by alphaDEC205 in vitro and in vivo.

  7. Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.

  8. CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

  9. Langerin-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 antibodies from the skin to the draining lymph nodes in steady state and inflammation.

  10. For production of cytotoxic T cells, DEC-205 and Clec9A, but not Clec12A, are effective targets for antibody-mediated delivery of antigens for vaccination, although only in the presence of adjuvants.

  11. Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

  12. show that Flt3L DC efficiently crosspresent HIV gag via the DEC-205 receptor, about 100 times more effective than non-targeted gag.

  13. Results suggest that DEC-205 provides an efficient receptor-based mechanism for dendritic cells to process proteins for MHC class I presentation in vivo, leading to tolerance in the steady state and immunity after dendritic cell maturation.

  14. This protein was detected in mouse Langerhans cells on epidermis separated by microwave irradiation.

  15. Dendritic cell targeting via the DEC205 receptor in the presence of anti-CD40 and poly(I:C) as maturation stimuli, induced strong human and mouse survivin-specific CD4+ T cell responses

  16. murine DEC-205 is a receptor for PLA of Yersinia pestis

  17. CD205 acts as a recognition receptor for dying cells, potentially providing an important pathway for the uptake of self-antigen in intrathymic and peripheral tolerance.

Human Lymphocyte Antigen 75 (LY75) interaction partners

  1. combined panel had the highest sensitivity and specificity at 96.3% and 100%, which was significantly or marginally higher than those of EZH2, C-KIT, and CD205 alone

  2. keratins are the cellular ligands of human DEC205.

  3. High LY75 expression is associated with metastasis of ovarian cancer.

  4. IL-6, DEC205, and CD86 can be predictive biomarkers for the respiratory and immune effects of ambient PM2.5.

  5. LY75 Gene Polymorphisms are Associated with Inflammatory Bowel Disease.

  6. results suggest that DEC205 is an immune receptor that recognizes apoptotic and necrotic cells specifically through a pH-dependent mechanism

  7. Variants in LY75 were associated with a Crohn's disease phenotype involving erythema nodosum.

  8. elevated in cholesteatoma

  9. DEC-205 is a cell surface receptor for CpG olligonucleotides.

  10. Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.

  11. The most significantly associated SNPs to type 2 diabetes mellitus in this study are expression SNPs to the lymphocyte antigen 75 gene, the ubiquitin-specific peptidase 36 gene, and the phosphatidylinositol transfer protein, cytoplasmic 1 gene.

  12. CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

  13. Upregulation of LY75 is associated with ovarian tumor.

  14. observed that TLR-mediated signaling increases DEC-205 expression levels without affecting receptor internalization

  15. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1

  16. DCs and DEC-205 can cross-present several different peptides from a single protein. Data supports testing of alphaDEC-205 fusion mAb as a protein-based vaccine.

  17. CD205 is a sensitive and specific marker for thymoma but its sensitivity to thymic carcinoma is lower than CD5 and CD117.

  18. targeting EBV nuclear antigen 1 to human DEC-205 receptor, in the presence of the DC maturation stimulus poly(I:C), expanded EBNA1-specific CD4 and CD8 memory T cells; these lymphocytes control the outgrowth of autologous EBV-infected B cells

  19. oxLDL uptake by DCs is mediated by the scavenger-receptors LOX-1, CD36, and CD205

  20. Induction of LY75 antigen is associated with relapsed chronic myeloid leukemia.

Lymphocyte Antigen 75 (LY75) Protein Profile

Protein Summary

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.

Gene names and symbols associated with Lymphocyte Antigen 75 Proteins (LY75)

  • lymphocyte antigen 75 (LY75)
  • lymphocyte antigen 75 (Cyan7822_2917)
  • lymphocyte antigen 75 (LY5)
  • lymphocyte antigen 75 (ly75)
  • CD205 protein (cd205)
  • lymphocyte antigen 75 (LOC100380704)
  • CD302 antigen (LOC100433861)
  • lymphocyte antigen 75 (LOC100483541)
  • lymphocyte antigen 75 (Ly75)
  • CD205 protein
  • CLEC13B protein
  • DEC-205 protein
  • DEC205 protein
  • GP200-MR6 protein
  • im:7150926 protein
  • Ly-75 protein
  • LY75 protein
  • LYT75 protein
  • MGC140308 protein
  • RGD1565962 protein
  • si:dkey-78p20.2 protein

Protein level used designations for Lymphocyte Antigen 75 Proteins (LY75)

lymphocyte antigen 75 , DEC-205/CD205 protein , DEC-205/CD205 , CD205 protein , DEC-205 protein , Lymphocyte antigen 75 , lymphocyte antigen 75-like , ly-75 , C-type lectin domain family 13 member B

GENE ID SPECIES
407236 Bos taurus
9739406 Cyanothece sp. PCC 7822
100060284 Equus caballus
100500738 Oncorhynchus mykiss
100462946 Takifugu rubripes
424192 Gallus gallus
459682 Pan troglodytes
488366 Canis lupus familiaris
504036 Danio rerio
595126 Sus scrofa
100101125 Felis catus
100380704 Salmo salar
100433861 Pongo abelii
100483541 Ailuropoda melanoleuca
17076 Mus musculus
4065 Homo sapiens
499800 Rattus norvegicus
101830769 Mesocricetus auratus
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