Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase Proteins (MGAT1)

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Additionally we are shipping Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase Antibodies (95) and Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MGAT1 4245 P26572
MGAT1 17308 P27808
Rat MGAT1 MGAT1 81519 Q09325
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Top Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase Proteins at

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 60 to 71 Days
Yeast Rabbit His tag   1 mg Log in to see 60 to 71 Days

MGAT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) Interaction Partners

Human Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) interaction partners

  1. In this study we showed that the activation of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway culminates in the upregulation of MGAT1 enzyme both at transcriptional and post-transcriptional levels. We also showed that overexpression of the beta-catenin (show CTNNB1 Proteins) gene (CTNNB1 (show CTNNB1 Proteins)) increased the promoter activity of MGAT1.

  2. The presence of the rs4285184 polymorphism of the MGAT1 gene increased the risk for developing body fat associated with obesity in the Mexican population.

  3. MGAT1 is downregulated in peripheral blood mononuclear cells of galactosaemia patients.

  4. The authors show here that the luminal domain of GnT1IP-L contains its MGAT1 inhibitory activity.

  5. UDP-galactose (show B4GALT1 Proteins) (SLC35A2 (show SLC35A2 Proteins)) and UDP-N-acetylglucosamine (show MGAT4B Proteins) (SLC35A3 (show SLC35A3 Proteins)) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).

  6. The IL2RA (show IL2RA Proteins) and IL7RA (show IL7R Proteins) variants had univariate association in MS and T1D, whereas the MGAT1 and CTLA-4 (show CTLA4 Proteins) variants associated with only MS or T1D, respectively.

  7. analysis of suppression of cancer progression by MGAT1 shRNA knockdown

  8. Genetic variants downstream MGAT1 seem to influence susceptibility to obesity. Moreover, these genetic variants affect the levels of serum unsaturated fatty acids and Delta desaturase indices, variables previously shown to correlate with obesity.

  9. The analysis enabled us to identify a new candidate gene, MGAT1, associated with weight in women.

Mouse (Murine) Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) interaction partners

  1. The MGAT1 interacts with DGAT2 (show DGAT2 Proteins), which serves to synergistically increase the TAG biosynthesis and LD expansion, leading to enhancement of lipid accumulation in the liver and fat.

  2. this study shows that loss of O-GlcNAc transferase blocks T cell progenitor renewal, malignant transformation and peripheral T cell clonal expansion

  3. Inhibition of hepatic Mogat1 (show MOGAT1 Proteins) improves hepatic metabolic abnormalities without attenuating liver inflammation and injury.

  4. Data from transgenic mice suggest that a lack of complex N- and O-glycans impairs early embryo development and viability in vivo leading to delayed implantation and embryo loss; Mgat1 and C1galt1 are required for embryo development and implantation.

  5. analysis of suppression of cancer progression by MGAT1 shRNA knockdown

  6. the MGAT1 pathway induced by hepatic PPARgamma (show PPARG Proteins) is critically important in the development of hepatic steatosis during diet-induced obesity

  7. Mgat1 mutant oocytes had an altered zona pellucida (ZP) that was thinner than the control ZP, and they did not possess complex N-glycans

  8. analysis of developmental and nutritional regulation of monoacylglycerol lipase (show MGLL Proteins) and monoacylglycerol acyltransferase

Fruit Fly (Drosophila melanogaster) Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) interaction partners

  1. MGAT1-dependent N-glycosylation shapes the synaptomatrix carbohydrate environment and endogenous lectin localization within this domain, to modulate retention of trans-synaptic signaling ligands driving synaptic scaffold recruitment during synaptogenesis.

  2. show that knockdown of Mgat1 in the central nervous system (CNS) of wild-type flies decreases locomotor activity and life span.

  3. beta1,2-N-acetylglucosaminyltransferase I-dependent N-glycans are required for locomotory activity, life span, and brain development in Drosophila

Cow (Bovine) Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) interaction partners

  1. N-acetylglucosaminyltransferase I activity in the oviduct may contribute to the induction of glycosylation and thereby contributing to the provision of the optimal microenvironment for fertilization and early development of the embryos.

Arabidopsis thaliana Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) interaction partners

Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT1) Protein Profile

Protein Summary

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.

Gene names and symbols associated with MGAT1

  • mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1)
  • mannoside acetylglucosaminyltransferase 1 (Mgat1)
  • Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1 (Mgat1)
  • mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1)
  • mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase S homeolog (mgat1.S)
  • alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (LOC410105)
  • mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (mgat1)
  • Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (mgat1)
  • alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (CGL1)
  • CG13431 protein
  • CGL protein
  • Dmel\\CG13431 protein
  • dMGAT1 protein
  • F20D10.360 protein
  • F20D10_360 protein
  • GB16928 protein
  • GlcNAc-TI protein
  • GlcNAcT1 protein
  • GLCT1 protein
  • GLYT1 protein
  • GNT-1 protein
  • GNT-I protein
  • GNTI protein
  • MGAT protein
  • Mgat-1 protein
  • MGAT1 protein

Protein level used designations for MGAT1

N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I , alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase , glcNAc-T I , GNT-I , CG13431-PA , Mgat1-PA , N-acetylglucosaminyltransferase I , MGAT1 gene for N-acetylglucosaminyltransferase , mannoside acetylglucosaminyltransferase 1 , alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase , UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I , mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase , Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

4245 Homo sapiens
17308 Mus musculus
37323 Drosophila melanogaster
81519 Rattus norvegicus
379038 Xenopus laevis
410105 Apis mellifera
462340 Pan troglodytes
491674 Canis lupus familiaris
496815 Xenopus (Silurana) tropicalis
534248 Bos taurus
707375 Macaca mulatta
100009521 Oryctolagus cuniculus
100172524 Pongo abelii
100196739 Salmo salar
100583691 Nomascus leucogenys
829981 Arabidopsis thaliana
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