Melan A Proteins (MLANA)

Involved in melanosome biogenesis by ensuring the stability of GPR143. Additionally we are shipping MLANA Antibodies (507) and MLANA Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MLANA 77836  
Rat MLANA MLANA 293890  
MLANA 2315 Q16655
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Top MLANA Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
Escherichia coli (E. coli) Human Un-conjugated 50 μg 2 to 3 Days
Escherichia coli (E. coli) Human His tag 100 μg 13 to 16 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
Escherichia coli (E. coli) Mouse Un-conjugated   50 μg 2 to 3 Days

MLANA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
Human , , ,
, , ,

More Proteins for Melan A (MLANA) Interaction Partners

Mouse (Murine) Melan A (MLANA) interaction partners

  1. Cell passaging severely reduced the expression of genes encoding markers typical of UM, including those of the prognostic gene signature. Marked differences between gene expression profiles of primary tumors and cell lines could be linked to the infiltrating immune and stromal cells in situ.

  2. MART-1 is a pigmentation gene that is required for melanosome biogenesis and/or maintenance.

  3. Results suggest that the MART-1::Cre line may serve as a novel and useful tool for functional studies in melanocytes and retinal pigment epithelium.

  4. OA1 interacts with MART-1 at early stages of melanogenesis to control melanosome identity and composition.

  5. mLANA and p53 have roles in virus replication

Human Melan A (MLANA) interaction partners

  1. work shows that antigen-specific and MHC-restricted gammadelta T cells can be generated in vitro and that MART-1-specific gammadelta T cells can also be found and cloned from the naive repertoire

  2. Expression of HMB45, MelanA and SOX10 is evident but exceedingly rare in non-small cell lung cancer cases

  3. Melan-A-stained slides shows definitive invasion.

  4. Report automated quantification of proliferation with automated hot-spot selection in phosphohistone H3/MART1 dual-stained stage I/II melanoma.

  5. Suggest MelanA-negative spindle-cell associated melanoma constitutes a distinct inflammatory phenotype correlated with dense infiltration of CD163 macrophages and loss of E-cadherin.

  6. Inhibin alpha-subunit, Melan A and MNF116 were not sensitive for pheochromocytomas.

  7. the presence of antibody and T-cell immune responses directed against the melanocyte-differentiation-antigens MART-1 (Melan-A), tyrosinase and gp100 in patients with melanoma-associated leucoderma, as compared to patients with vitiligo.

  8. Knockdown of T-bet expression in Mart-127-35 -specific T-cell-receptor-engineered human CD4(+) CD25(-) and CD8(+) T cells attenuates effector function.

  9. Melan-A was useful to confirm the diagnosis of lentigo maligna in early lesions and to differentiate these from chronically sun-damaged skin.

  10. Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells.

  11. Comprehensive characterization of the marginal and joint distributions for S100, HMB-45, and Melan-A across a large series of cutaneous melanomas revealed diversity of expression across this group of antigens.

  12. melan A (A103) is not expressed in mesotheliomas

  13. Report diagnostic role of immunohistochemical staining for Melan-A in evaluating primary melanoma and, specifically, in situ melanoma cases.

  14. In this study, production of the C terminus of the Melan-A(26-35) epitope requires cleavage within a hydrophobic stretch, after V35. Hence, the standard proteasome is the only proteasome able to produce the C terminus of this epitope.

  15. naturally occurring MART-1 melanoma antigen can be taken-up from dying melanoma cells into DC or MAK and both cell types can induce specific CD8(+) T cell cross-presentation thereafter.

  16. The presence of circulating T cells responding to Melan-A or NY-ESO-1 had strong independent prognostic impact on survival in advanced melanoma.

  17. The modified melan-A long peptides (not their wild-type counterparts) give rise to highly sustained cross-presentation capacity by monocyte-derived dendritic cells and could be used as tumor vaccines for treatment of melanoma patients.

  18. Aberrant expression of Melan-A and MART-1 in AFX and undifferentiated pleomorphic sarcoma of the skin represents an important diagnostic pitfall with potential for misdiagnosis as melanoma.

  19. MART-1- and gp100-expressing and -non-expressing melanoma cells are equally proliferative in tumors and clonogenic in vitro.

  20. we established several CD4 T-cell clones that recognized a peptide that is embedded within Melan-A/MART-121-50, in a HLA-DPB1*0501 restricted manner

MLANA Protein Profile

Protein Summary

Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

Gene names and symbols associated with Melan A Proteins (MLANA)

  • melan-A (Mlana)
  • melan-A (MLANA)
  • A930034P04Rik protein
  • MART-1 protein
  • MART1 protein

Protein level used designations for Melan A Proteins (MLANA)

melanoma antigen recognized by T-cells 1 , melanoma associated antigen recognized by T-cells 1 , antigen LB39-AA , antigen SK29-AA , protein Melan-A

77836 Mus musculus
293890 Rattus norvegicus
2315 Homo sapiens
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