Melanoma Antigen Family A, 4 Proteins (MAGEA4)

MAGEA4 is a member of the MAGEA gene family. Additionally we are shipping MAGEA4 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse MAGEA4 MAGEA4 17140  
Rat MAGEA4 MAGEA4 689858  
MAGEA4 4103 P43358
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Top MAGEA4 Proteins at

Showing 5 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 20 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
Human Un-conjugated   1 mg Log in to see 6 Days

MAGEA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Melanoma Antigen Family A, 4 (MAGEA4) Interaction Partners

Mouse (Murine) Melanoma Antigen Family A, 4 (MAGEA4) interaction partners

  1. a cleaved form of MAGE-A4 binds to Miz-1 (show ZBTB17 Proteins) and induces apoptosis

Human Melanoma Antigen Family A, 4 (MAGEA4) interaction partners

  1. some autoantibodies, such as anti-MAGEA4, anti-CTAG1 (show CTAG1B Proteins) or anti-TP53 (show TP53 Proteins) and their combinations could possibly contribute to the development of cancer early detection tests (not necessarily restricted to gastric cancer) when being combined with other markers.

  2. Anti-MAGEA4 exhibited the highest sensitivity for detecting early stage colorectal cancer (CRC (show CALR Proteins)) and advanced adenoma.

  3. High MAGE-A4 expression is associated with Lung Cancer.

  4. Results found concomitant overexpression of MAGEA4 and TWIST1 (show TWIST1 Proteins) in esophageal squamous cell carcinoma (ESCC). Also, it showed a correlation between MAGEA4 and TWIST1 (show TWIST1 Proteins) expression, which was found as indirect binding of TWIST1 (show TWIST1 Proteins) to the E-boxes in the MAGEA4 promoter revealing transcriptional upregulation of MAGEA4 by TWIST1 (show TWIST1 Proteins).

  5. Results support the potential utility of NY-ESO-1 (show CTAG1B Proteins), PRAME (show PRAME Proteins), and MAGEA4 as targets for immunotherapy and as ancillary prognostic parameters in synovial sarcomas.

  6. Data show that overall survival (OS) was significantly lower for patients expressing pan-MAGE (show MAGEB10 Proteins) or MAGE (show MAGEB10 Proteins)-A1/A3/A4 in both independent cohorts.

  7. the crystal structures of MAGE-A3 (show MAGEA3 Proteins) and MAGE-A4

  8. CTAs (MAGE-A4, NY-ESO-1, MAGE-A10) were more likely expressed in patients with squamous cell carcinoma of the lung and when CTAs combined with CD133, they can be better prognostic factors.

  9. HLA class I (show MICA Proteins) loss in smokers or patients with the MAGE-A4 gene was a prognostic factors in non-small cell lung cancer .

  10. Expression of MAGE-A4 may make immunotherapeutic intervention possible in selected patients with thyroid cancer.

MAGEA4 Protein Profile

Protein Summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Gene names and symbols associated with MAGEA4

  • melanoma antigen, family A, 4 (Magea4)
  • MAGE family member A4 (MAGEA4)
  • CT1.4 protein
  • MAGE-41 protein
  • Mage-a4 protein
  • MAGE-X2 protein
  • MAGE4 protein
  • MAGE4A protein
  • MAGE4B protein
  • MAGEA4 protein

Protein level used designations for MAGEA4

melanoma antigen family A, 4 , MAGE-4 antigen , MAGE-41 antigen , MAGE-X2 antigen , cancer/testis antigen 1.4 , cancer/testis antigen family 1, member 4 , melanoma-associated antigen 4

17140 Mus musculus
689858 Rattus norvegicus
465910 Pan troglodytes
4103 Homo sapiens
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