anti-Melanoma Inhibitory Activity Protein 2 (MIA2) Antibodies

The protein encoded by MIA2 is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Additionally we are shipping MIA2 Proteins (16) and MIA2 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MIA2 4253 O15320
MIA2 338320 Q91ZV0
MIA2 362743  
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Top anti-MIA2 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CTAGE5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate CTAGE5 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells WB Suggested Anti-CTAGE5  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate  CTAGE5 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CTAGE5 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate CTAGE5 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells CTAGE5 antibody - middle region          Formalin Fixed Paraffin Embedded Tissue:  Human Liver Tissue    Observed Staining:  Cytoplasm in hepatocytes   Primary Antibody Concentration:  1:600    Secondary Antibody:  Donkey anti-Rabbit-Cy3    Secondary Antibody Concentration:  1:200    Magnification:  20X    Exposure Time:  0.5 - 2.0 sec 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CTAGE5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate Host:  Rabbit  Target Name:  CTAGE5  Sample Type:  HepG2  Antibody Dilution:  1.0ug/ml  CTAGE5 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CTAGE5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Hela cell lysate CTAGE5 antibody - middle region          Formalin Fixed Paraffin Embedded Tissue:  Human Liver Tissue    Observed Staining:  Membrane in hepatocytes   Primary Antibody Concentration:  1:100    Secondary Antibody:  Donkey anti-Rabbit-Cy3    Secondary Antibody Concentration:  1:200    Magnification:  20X    Exposure Time:  0.5 - 2.0 sec 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MIA2 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of MIA2 staining in human liver formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of MIA2 expression in HepG2 (A), HuvEc (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB CTAGE5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTAGE5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. CTAGE5 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CTAGE5 antibody detected the CTAGE5 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Available
$363.46
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

Top referenced anti-MIA2 Antibodies

  1. Human Polyclonal MIA2 Primary Antibody for IHC, IHC (p) - ABIN4300739 : Falk, Ramström, Eriksson, Uhlén, Wernérus, Hober: Targeted protein pullout from human tissue samples using competitive elution. in Biotechnology journal 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MIA2 Primary Antibody for IHC, IHC (p) - ABIN4300738 : Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006 (PubMed)

More Antibodies against MIA2 Interaction Partners

Human Melanoma Inhibitory Activity Protein 2 (MIA2) interaction partners

  1. These data showed that the NRZ tether is required for TANGO1 to assemble into a ring and indicated that stable complexes of TANGO1, cTAGE5 and TANGO1-short, recruit the tether.

  2. TANGO1/CTAGE5 receptor serves as a polyvalent template for assembly of large COPII coats.

  3. In this study, we identified specific and critical residues in the Sec12-binding region of cTAGE5 (E75A K76A, K89A, and S97A) and confirmed that cTAGE5-mediated Sec12 accumulation at ER exit sites is required for collagen VII secretion.

  4. Data indicate that MIA2 represents a potential novel acute phase protein and MIA2 expression responds to liver damage in chronic liver diseases.

  5. The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma.

  6. population and bioinformatic analysis of MGEA6 P521A variation as a risk factor for Fahr's disease; genetic screen data show this mutation is very rare; bioinformatics analysis provided conflicting findings

  7. cTAGE5 forms a complex with TANGO1 (MIA3), a previously characterized cargo receptor for collagen VII

  8. HBx activates hepatoma cell growth and proliferation through repression of the potential tumor suppressor MIA2.

  9. 22 members of an Iranian family with basal ganglia calfication as well as 100 controls were genotyped for the C>G P521A variant of CTAGE5, but none were found.

  10. Findings suggest that the roles of MIA2 might be based on the variety of the integrins and the subtypes of mitogen-activated protein kinase in oral carcinoma.

  11. Sec12 recruitment to endoplasmic reticulum exit sites is organized by its direct interaction with cTAGE5, a previously characterized collagen cargo receptor component, which functions together with TANGO1 at endoplasmic reticulum exit sites.

  12. These findings define an interaction between the common MIA2(I141M) variant and the ER stress/UPR system and specify a subgroup of PDAC patients who are more likely to benefit from adjuvant chemotherapy.

Mouse (Murine) Melanoma Inhibitory Activity Protein 2 (MIA2) interaction partners

  1. Conditional knockout of cTAGE5/MEA6 in the brain leads to severe defects in neural development, including deficits in dendrite outgrowth and branching, spine formation and maintenance, astrocyte activation, and abnormal behaviors

  2. cTAGE5 deletion in pancreatic beta cells impairs proinsulin trafficking and insulin biogenesis in mice.

  3. Mia2 is a novel, hepatic, endoplasmic reticulum-to-Golgi trafficking protein that regulates cholesterol metabolism.

MIA2 Antigen Profile

Protein Summary

The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MIA2

  • melanoma inhibitory activity 2 (MIA2) antibody
  • CTAGE family, member 5 (ctage5) antibody
  • melanoma inhibitory activity 2 (Mia2) antibody
  • MEA6 antibody
  • MGEA antibody
  • MGEA6 antibody
  • MGEA11 antibody
  • zgc:56047 antibody

Protein level used designations for MIA2

cTAGE family member 5 , cutaneous T-cell lymphoma-associated antigen 5 , meningioma expressed antigen 6 (coiled-coil proline-rich) , meningioma-expressed antigen 6/11 , protein cTAGE-5 , melanoma inhibitory activity protein 2

GENE ID SPECIES
4253 Homo sapiens
393281 Danio rerio
338320 Mus musculus
362743 Rattus norvegicus
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