Melanoregulin Proteins (MREG)

May function in membrane fusion and regulate organelle biogenesis (By similarity). Additionally we are shipping MREG Antibodies (48) and MREG Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MREG 55686 Q8N565
MREG 381269 Q6NVG5
Rat MREG MREG 501162  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top MREG Proteins at

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Escherichia coli (E. coli) Human His tag 50 μg 13 to 16 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Yeast Xenopus tropicalis His tag   1 mg 60 to 71 Days
Yeast Zebrafish His tag   1 mg 60 to 71 Days

MREG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Melanoregulin (MREG) Interaction Partners

Human Melanoregulin (MREG) interaction partners

  1. Taken together, MREG regulates thyroid cancer cell invasion and proliferation through PI3K/Akt-mTOR signaling pathway. MREG may serve as a promising therapeutic strategy for thyroid cancer.

  2. MREG-dependent processing links both autophagic and phagocytic processes in LC3-associated phagocytosis. MREG participates in coordinating the association of phagosomes with LC3 for content degradation with the MREG loss leading to phagosome accumulation.

Mouse (Murine) Melanoregulin (MREG) interaction partners

  1. Mreg contains six alpha helices forming a fishhook-like fold in which positive and negative charges occupy opposite sides of the protein's surface and sandwich a putative, cholesterol recognition sequence (CRAC motif). Mreg containing a point mutation within its CRAC motif still targets to late endosomes/lysosomes, but no longer promotes their microtubule minus end-directed transport.

  2. Single membrane POS containing phagosomes recruit endogenous LC3 in an ATG5-dependent manner that is dependent on MREG. In the Mregdsu/dsu RPE, Atg5/12 and LC3 were increased relative to levels in the Mreg+/+ at all time points relative to light onset.

  3. This study demonistrated that Loss of melanoregulin (MREG) enhances cathepsin-D secretion by the retinal pigment epithelium.

  4. The product of the Mreg(dsu) locus, melanoregulin (MREG), interacts both with members of BLOC-2 complex and with ocular albinism in regulating melanosome size.

  5. Mreg regulates microtubule-dependent retrograde melanosome transport through the dynein-dynactin motor complex.

  6. multiple palmitoylation serves to stably anchor melanoregulin in the melanosome membrane.

  7. Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes.

  8. dsu identifies a unique protein involved in pigmentation of the mammalian hair

  9. melanoregulin regulates peripherin-2 function

  10. Results suggest that melanoregulin (MREG) is required for lysosome maturation and support a role for MREG in intracellular trafficking.

MREG Protein Profile

Protein Summary

May function in membrane fusion and regulate organelle biogenesis (By similarity).

Gene names and symbols associated with Melanoregulin Proteins (MREG)

  • melanoregulin (MREG)
  • melanoregulin (mreg)
  • melanoregulin L homeolog (mreg.L)
  • melanoregulin (Mreg)
  • zgc:91968 (zgc:91968)
  • dsu protein
  • Gm974 protein
  • MGC115366 protein
  • mreg protein
  • RGD1562333 protein
  • Wdt2 protein
  • wu:fk68c04 protein

Protein level used designations for Melanoregulin Proteins (MREG)

melanoregulin , whn-dependent transcript 2-like , dilute suppressor protein homolog , whn-dependent transcript 2 , dilute suppressor protein

424013 Gallus gallus
459928 Pan troglodytes
549186 Xenopus (Silurana) tropicalis
610230 Canis lupus familiaris
613445 Bos taurus
695056 Macaca mulatta
735112 Xenopus laevis
55686 Homo sapiens
381269 Mus musculus
501162 Rattus norvegicus
431714 Danio rerio
Selected quality suppliers for MREG Proteins (MREG)
Did you look for something else?