Membrane-Spanning 4-Domains, Subfamily A, Member 1 Proteins (MS4A1)

MS4A1 encodes a member of the membrane-spanning 4A gene family. Additionally we are shipping CD20 Antibodies (869) and CD20 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MS4A1 931 P11836
MS4A1 12482 P19437
Rat MS4A1 MS4A1 309217  
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Top CD20 Proteins at

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
Human Cells Human His tag 10 μg 14 to 16 Days
Human Cells Ferret His tag 100 μg 14 to 16 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Yeast Human His tag 50 μg 8 to 11 Days
Yeast Mouse His tag 50 μg 8 to 11 Days
Escherichia coli (E. coli) Mouse His-SUMO Tag 50 μg 11 Days
Baculovirus infected Insect Cells Human His tag 50 μg 13 to 16 Days
Wheat germ Human GST tag 2 μg 11 to 12 Days

MS4A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , ,
Mouse (Murine) , ,
, , ,

Top referenced CD20 Proteins

  1. Human CD20 Protein expressed in Wheat germ - ABIN1311399 : Chen, Page, Schwartz, Lee, DeWall, Sikkema, Wang: False-positive immunogenicity responses are caused by CD20+ B cell membrane fragments in an anti-ofatumumab antibody bridging assay. in Journal of immunological methods 2013 (PubMed)

More Proteins for Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) Interaction Partners

Human Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) interaction partners

  1. Older age and CD20 expression are significant and favorable independent prognostic factors of HHV-8-negative effusion-based lymphoma.

  2. Case Report: indolent T-cell lymphoproliferative disorder with aberrant CD20 expression involving the gastrointestinal tract and bone marrow.

  3. Our study found that a small subset of papillary thyroid carcinomas (<10%, mainly of classic variant) exhibited aberrant membranous expression of CD20

  4. Our results support the fact that CD200 can be added to routine Chronic lymphoproliferative disorders panel as it is useful in subcategorizing them. However, inclusion of CD20 ABC to routine panel does not seem plausible but may be done for difficult diagnostic cases or where anti-CD20 therapy is planned.

  5. showed here that 3' UTR NOTCH1 mutations are associated with low CD20 expression and with relative resistance to anti-CD20 immunotherapy in vitro

  6. We conclude that the relationship between complement-regulatory proteins CFHR1 and CFHR3 and response to anti-CD20 mAb therapy varies based on the specific anti-CD20 mAb used.

  7. the immunohistochemical staining patterns of CD3 and CD20 in Malignant Lymphoma Cells, were investigated.

  8. Limiting the antibody-induced induction of immunosuppressive reactive oxygen species may improve the anti-leukemic efficacy of anti-CD20 therapy in chronic lymphocytic leukemia.

  9. Case Report: primary cutaneous T-cell lymphoma with aberrant CD20 expression.

  10. Data suggest that insulitis (destruction of pancreatic beta-cells and their ability to produce/secrete insulin) occurs in two distinct profiles in type 1 diabetes; these differ in proportion of CD20-positive B-lymphocytes (relative to CD4-positive T-lymphocytes) present within the infiltrate; greater infiltration of CD20-positive B-lymphocytes leads to more aggressive disease progression.

  11. PZ-DHA also arrested MDA-MB-231 cell division at the G2/M phase and down-regulated expression of cyclin B1 and cyclin-dependent kinase 1 (CDK1)

  12. there is a high CD23a/CD23b ratio of chronic lymphocytic leukemia cells, which demonstrates that in a subset of CLL cases, low CD23 expression together with high CD20 and CD38 expressions may serve as a surrogate for trisomy 12

  13. IL-17-producing pathogenic T lymphocytes co-express CD20 in primary Sjogren's syndrome patients.

  14. Studies indicate that CD20 antigen expression is absent in a variety of diffuse large B cell lymphomas (DLBCLs), including plasmablastic lymphoma, primary effusion lymphoma, anaplastic lymphoma, kinase-positive DLBCL, and large B cell lymphoma arising in human herpesvirus 8-associated multicentric Castleman disease.

  15. lipid formulations based on a polyplex or lipoplex backbone additionally equipped with anti-CD20 antibodies are promising non-viral vectors for specific oligonucleotide transfer into human tumor cells.

  16. The ABC values obtained for CD20 expression levels using PE, APC, or PerCP Cy5.5 are consistent over the five different instrument platforms for any given apparently healthy donor independent of the fluorochrome used

  17. Data indicate that Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukemia (ALL) patients who presented with cyclin dependent kinase inhibitor 2A/B (CDKN2A/B) deletion showed a higher rate of CD20 antigen expression.

  18. the findings demonstrate that treatment with anti-CD20-hIFNalpha reverses resistance of B-NHL

  19. Case Report: aberrant CD20 expression by skin-infiltrating T cells using multispectral imaging.

  20. Microenvironment CD20 + cells seem to play a favorable prognostic role in classical Hodgkin Lymphoma. Depletion of CD20 + cells together with an increase of TAMs identifies a group of patients with high-risk disease.

Mouse (Murine) Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) interaction partners

  1. Our findings indicate that anti-CD20-IFNalpha eradicates B-cell lymphoma by employing tumor cells as antigen-presenting cells to reactivate tumor-infiltrating CD8(+) T cells and synergizing with anti-PD-L1 treatment

  2. Galectin-1 has a role in driving lymphoma CD20 immunotherapy resistance in a mouse model

  3. Results indicate that an antigen-specific B cell response towards intracellular pathogens can be generated during anti-CD20 depletion therapy.

  4. this study demonstrates a role for CD20 in B cell activation and T-dependent humoral immunity.

  5. CD20 is required for store-operated calcium entry in C2C12 myoblasts.

  6. immunization of mice with the CD20 extracellular domain-6 using Freund's or QS-21 adjuvants was shown to exert significant biological effects in vivo with the pronounced depletion of splenic B cells.

  7. type I CD20 antibody cytotoxicity critically depends on Fc receptor ITAM signaling

  8. CD20 deficiency in humans results in impaired T cell-independent antibody responses.

  9. review of structure, function, tissue and cell distribution

  10. Anti-CD20 antibodies rapidly depleted the vast majority of circulating and tissue B cells in an isotype-restricted manner dependent on effector cell Fc receptor expression.

  11. expression in bacterial cells; isolation and biophysical and structural studies

  12. In mice treated with anti-CD20 mAb, development of arthritis was significantly reduced in comparison to control mAb-treated mice

  13. involvement of CD20 in calcium influx

Rhesus Monkey Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) interaction partners

  1. Data show that the CD1c+ cells were found to be mononuclear leukocytes rather than granulocytes, and most of them expressed CD20.

CD20 (MS4A1) Protein Profile

Protein Summary

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

Gene names and symbols associated with MS4A1

  • membrane spanning 4-domains A1 (MS4A1)
  • membrane-spanning 4-domains, subfamily A, member 1 (Ms4a1)
  • membrane spanning 4-domains A1 (Ms4a1)
  • membrane-spanning 4-domains, subfamily A, member 1 (MS4A1)
  • membrane spanning 4-domains A1 (ms4a1)
  • B-lymphocyte antigen CD20 (LOC101694281)
  • AA960661 protein
  • B1 protein
  • bp35 protein
  • cd20 protein
  • cd20-like protein
  • CVID5 protein
  • leu-16 protein
  • Ly-44 protein
  • MS4A1 protein
  • ms4a2 protein
  • ms4a4c protein
  • S7 protein

Protein level used designations for MS4A1

B-lymphocyte antigen CD20 , B-lymphocyte cell-surface antigen B1 , CD20 antigen , CD20 receptor , leukocyte surface antigen Leu-16 , B-cell differentiation antigen Ly-44 , lymphocyte antigen 44 , membrane-spanning 4-domains, subfamily A, member 2 , membrane-spanning 4-domains, subfamily A, member 1 , membrane-spanning 4-domains subfamily A member 1 , membrane-spanning 4-domains, subfamily A, member 4C , B-lymphocyte surface antigen B1 , Membrane-spanning 4-domains subfamily A member 1 , CD20 cell surface protein

931 Homo sapiens
12482 Mus musculus
309217 Rattus norvegicus
451223 Pan troglodytes
485430 Canis lupus familiaris
496881 Xenopus (Silurana) tropicalis
100059000 Equus caballus
100357719 Oryctolagus cuniculus
505653 Bos taurus
100627952 Sus scrofa
102118491 Macaca fascicularis
696843 Macaca mulatta
101694281 Mustela putorius furo
494216 Felis catus
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