More product categories related to MGST1 ELISA Kit
More ELISA Kits for MGST1 Interaction Partners
Zebrafish Microsomal Glutathione S-Transferase 1 (MGST1) interaction partners
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high expression of MGST1 was detected in regions of active hematopoiesis and co-expressed with markers for hematopoietic stem cells. Further, morpholino-mediated knock-down of MGST1 led to a significant reduction of differentiated hematopoietic cells both from the myeloid and the lymphoid lineages.
Human Microsomal Glutathione S-Transferase 1 (MGST1) interaction partners
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High MGST1 expression is associated with Bendamustine-resistance in Mantle Cell Lymphoma.
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Significant association for germline variations only in the COX pathway (specifically in the antioxidant microsomal glutathione S-transferase 1 [MGST1] gene), with risk for Barrett's esophagus and the combined outcome of Barrett's esophagus and esophageal adenocarcinoma was found.
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This study provides the most comprehensive evaluation of inflammation-related germline variation in relation to risk of BE/OA and suggests that variants in MGST1 influence disease susceptibility.
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The MSGT1 displays a preexisting dynamic equilibrium between high- and low-activity forms.
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possibly marked variations in NB mitochondrial homeostasis, they also imply that the results of these earlier studies using NB cells are not transferable to other tumor and cell types that express MGST1 at high concentrations.
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Differential expression of SOD2, ALDH1A1, and MGST1 genes in the anterior lens capsules of patients with pseudoexfoliation syndrome suggest that diseased tissue appears to respond to the previously reported oxidative stress.
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The results suggest that MGST1 gene polymorphisms as one of environment gene may contribute to colorectal cancer risk in younger ages.
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MGST1 protects cells (and mitochondria) by both conjugation and glutathione peroxidase functions. A new protective mechanism against cisplatin is also indicated
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Polymorphisms in microsomal glutathione s transferase is associated with laryngeal cancer
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The results indicate that Sp1 is the protein mediating the basal transcription of MGST1
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Genes encoding KU70, MGST1 and BIK show age-related mRNA expression levels in hematopoietic stem cells.
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As an addition to the high-density SNP (single-nucleotide polymorphism) maps of 12 glutathione S-transferase and related genes reported earlier, a SNP map of the microsomal glutathione S-transferase 1 (MGST1) gene is provided.
Mouse (Murine) Microsomal Glutathione S-Transferase 1 (MGST1) interaction partners
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The impact of MGST1 on hematopoiesis was also shown in hematopoietic stem/progenitor cells (HSPC) isolated from mice, where it was expressed at high levels. Upon promoting HSPC differentiation, lentiviral shRNA MGST1 knockdown significantly reduced differentiated, dedicated cells of the hematopoietic system.
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identification of the promoter region and a comprehensive examination of tissue expression of MGST1
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MGST1 is a dominant, highly expressed enzyme in mouse retinal pigment epithelium (RPE) microsomes that displays an important protective function against oxidative insult in the RPE that decreases with age.
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Gst genes are extensively downregulated in primary but not metastatic TRAMP tumors.
Cow (Bovine) Microsomal Glutathione S-Transferase 1 (MGST1) interaction partners
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Results from DNA and RNA sequence-based association mapping implicate MGST1, a gene with no obvious mechanistic relationship to milk composition regulation, as causally involved in these processes.
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MGST1 is highly expressed in bovine retinal pigment epithelium (RPE) microsomes and displays an important protective function against oxidative insult in the RPE.
MGST1 Antigen Profile
Antigen Summary
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.
Gene names and symbols associated with MGST1
- microsomal glutathione S-transferase 1 L homeolog (mgst1.L) antibody
- microsomal glutathione S-transferase 1.1 (mgst1.1) antibody
- microsomal glutathione S-transferase 1 pseudogene (LOC473380) antibody
- microsomal glutathione S-transferase 1 (MGST1) antibody
- microsomal glutathione S-transferase 1 (mgst1) antibody
- microsomal glutathione S-transferase 1 (CpipJ_CPIJ015233) antibody
- microsomal glutathione S-transferase 1 (CpipJ_CPIJ018241) antibody
- microsomal glutathione S-transferase 1 (Mgst1) antibody
- 1500002K10Rik antibody
- Gst antibody
- GST12 antibody
- MGST antibody
- MGST-I antibody
- MGST1 antibody
- zgc:101898 antibody
Protein level used designations for MGST1
microsomal glutathione S-transferase 1 , glutathione S-transferase 12 , microsomal GST-1 , microsomal GST-I , glutathione S-transferase
GENE ID | SPECIES |
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414684 | Xenopus laevis |
449784 | Danio rerio |
473380 | Pan troglodytes |
477683 | Canis lupus familiaris |
496690 | Xenopus (Silurana) tropicalis |
6048852 | Culex quinquefasciatus |
6052371 | Culex quinquefasciatus |
4257 | Homo sapiens |
56615 | Mus musculus |
171341 | Rattus norvegicus |
493719 | Bos taurus |
397567 | Sus scrofa |
418178 | Gallus gallus |
100736210 | Cavia porcellus |
100340829 | Oryctolagus cuniculus |
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