anti-Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) Antibodies

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Additionally we are shipping MICAL1 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MICAL1 64780 Q8TDZ2
MICAL1 171580 Q8VDP3
MICAL1 294520 D3ZBP4
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Top anti-MICAL1 Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
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Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 7 to 9 Days
$507.83
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Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MICAL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MICAL1. Flow cytometric Analysis of Hela cells, using anti-MICAL1 antibody (ABIN2453287), (Red), compared to a nonspecific negative control antibody (TA50011), (Blue). 0.1 mL Log in to see Available
$451.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MICAL1 mouse monoclonal antibody. (ABIN2453288) Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-MICAL1 mouse monoclonal antibody. (ABIN2453288) 0.1 mL Log in to see Available
$451.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of Jurkat cells, using MICAL1 antibody. ABIN6273008 at 1/100 staining Human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Western Blot: MICAL1 Antibody [NBP2-17287] - Sample (30 ug of whole cell lysate) A: HCT116 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MICAL1 is 0.03 ng/ml as a capture antibody. MICAL1 monoclonal antibody (M06), clone 3D12. Western Blot analysis of MICAL1 expression in Jurkat. 100 μg Log in to see 11 to 12 Days
$440.00
Details

Top referenced anti-MICAL1 Antibodies

  1. Human Polyclonal MICAL1 Primary Antibody for WB - ABIN528693 : Dutta, Donaldson: Sorting of Clathrin-Independent Cargo Proteins Depends on Rab35 Delivered by Clathrin-Mediated Endocytosis. in Traffic (Copenhagen, Denmark) 2015 (PubMed)

More Antibodies against MICAL1 Interaction Partners

Human Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) interaction partners

  1. Methionine oxidation is regulated in vivo by monooxygenases of the MICAL family. (Review)

  2. describe methods to characterize MICAL-mediated F-actin disassembly using in vitro assays with purified proteins

  3. The results provide evidence that MICAL1 plays an essential role in the activation of ROS (show ROS1 Antibodies)/Akt (show AKT1 Antibodies) signaling and cell invasive phenotype and identify a novel link between RAB35 (show RAB35 Antibodies) and MICAL1 in regulating breast cancer cell invasion.

  4. Data suggest that Sema6A (show SEMA6A Antibodies) and Mical1 may represent new potential therapeutic targets in BRAFV600E melanoma.

  5. The MICAL1 directly induce oxidation of actin molecules, leading to actin depolymerization. ROS (show ROS1 Antibodies) production by MICAL1 also causes oxidation of collapsin response mediator protein-2 (show DPYSL2 Antibodies) which subsequently undergoes phosphorylation.

  6. although MICAL1 is auto-inhibited by its C-terminal coiled-coil region, MICAL2 remains constitutively active and affects stress fibers, suggesting differential but complementary roles for MICAL1 and MICAL2 in actin microfilament regulation

  7. Faint and scattered immunoreactivity for Mical-1 is observed in neurons of the neocortex of the temporal lobe epilepsy group, while strong immunoreactivity for Mical-1 is shown in control subjects.

  8. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST (show MAP3K10 Antibodies)-NDR (show STK38 Antibodies) signaling.

  9. a CasL interacting molecule that associates with vimentin (show VIM Antibodies)

  10. MICAL-1 isoforms with their multidomain structure are novel rab1 (show RAB1A Antibodies) interacting proteins that function as scaffold proteins connecting different components in the cell.

Mouse (Murine) Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1) interaction partners

  1. esults suggest that the CH domain, which is loosely connected to the MO domain by a flexible linker and is far away from the catalytic site, couples F-actin to the enhancement of redox activity of MICALMO-CH by a cooperative mechanism involving a trans interaction between adjacently bound molecules.

  2. MICAL-1 regulates the targeting of secretory vesicles containing immunoglobulin superfamily cell adhesion molecules (IgCAMs) to the neuronal growth cone membrane through its ability to control the actin cytoskeleton using redox chemistry.

  3. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST-NDR (show STK38 Antibodies) signaling.

MICAL1 Antigen Profile

Protein Summary

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L\; acts by antagonizing STK38 and STK38L activation by MST1/STK4 (By similarity).

Gene names and symbols associated with MICAL1

  • microtubule associated monooxygenase, calponin and LIM domain containing 1 (MICAL1) antibody
  • microtubule associated monooxygenase, calponin and LIM domain containing 1 (Mical1) antibody
  • microtubule associated monooxygenase, calponin and LIM domain containing 1 (mical1) antibody
  • MICAL antibody
  • MICAL-1 antibody
  • Nical antibody
  • zgc:171928 antibody

Protein level used designations for MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1 , CasL interacting molecule , NEDD9 interacting protein with calponin homology and LIM domains , NEDD9-interacting protein with calponin homology and LIM domains , molecule interacting with CasL protein 1 , protein-methionine sulfoxide oxidase MICAL1 , CasL interacting molecule MICAL , molecule interacting with CasL 1 , microtubule associated monooxygenase, calponin and LIM domain containing 1

GENE ID SPECIES
100066627 Equus caballus
100232670 Taeniopygia guttata
64780 Homo sapiens
171580 Mus musculus
294520 Rattus norvegicus
568573 Danio rerio
100153346 Sus scrofa
508306 Bos taurus
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