Mitochondrial Fission Factor Proteins (MFF)

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission.

list all proteins Gene Name GeneID UniProt
Human MFF MFF 56947 Q9GZY8
Mouse MFF MFF 75734 Q6PCP5
Rat MFF MFF 301563 Q4KM98
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Top Mitochondrial Fission Factor Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$2,480.50
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,480.50
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,480.50
Details

More Proteins for Mitochondrial Fission Factor (MFF) Interaction Partners

Human Mitochondrial Fission Factor (MFF) interaction partners

  1. expressions of TIA-1 (show TIA1 Proteins) and MFF were augmented in the cancerous liver tissues compared to the corresponding non-tumor tissues at mRNA and protein level, while the levels of miR (show MLXIP Proteins)-200a-3p and miR (show MLXIP Proteins)-27a/b were relatively lower in the cancerous liver tissues

  2. We suggest that, even if laboratory findings are not indicative of mitochondrial or peroxisomal dysfunction, the co-occurrence of optic and/or peripheral neuropathy with seizures warrants genetic testing for MFF mutations

  3. membrane-anchored Mff differentially regulates various Drp1 (show CRMP1 Proteins) isoforms.

  4. Data show that expression of MFF protein, miR-593-5p and BRCA1 protein correlates with cisplatin sensitivity and survival of tongue squamous cell carcinoma (TSCC).

  5. loss of Mff results in failure of Parkin (show PARK2 Proteins) translocation and final clearance of damaged mitochondria

  6. Mitochondrial fission factor (MFF) mRNA is a direct target of miR (show MLXIP Proteins)-27, whose ectopic expression decreases MFF expression through binding to its 3'-untranslated region.

  7. MiD49 (show SMCR7 Proteins) and MiD51 (show SMCR7L Proteins) can act independently of Mff and Fis1 (show FIS1 Proteins) in Drp1 (show CRMP1 Proteins) recruitment and suggest that they provide specificity to the division of mitochondria.

  8. TRAP1 (show TRAP1 Proteins) controls mitochondrial fusion/fission balance through Drp1 (show CRMP1 Proteins) and Mff expression.

  9. PEX11 proteins attract both Mff and human Fis1 (hFis1 (show FIS1 Proteins)) to their site of action.

  10. MFF over-expression results in extensive mitochondrial fragmentation, driving mitochondrial dysfunction. MFF fibroblasts undergo oxidative stress, with increased ROS (show ROS1 Proteins) production, and the onset of autophagy and mitophagy.

Mouse (Murine) Mitochondrial Fission Factor (MFF) interaction partners

  1. mitochondrial fission factor

  2. MiD51 (show SMCR7L Proteins) can suppress Mff-dependent enhancement of Drp1 (show CRMP1 Proteins) GTPase (show RACGAP1 Proteins) activity.

  3. Mff cannot bind to assembly-deficient mutants of Drp1 (show CRMP1 Proteins), suggesting that Mff selectively interacts with higher-order complexes of Drp1 (show CRMP1 Proteins).

  4. membrane-anchored Mff differentially regulates various Drp1 (show CRMP1 Proteins) isoforms.

  5. These findings provide a mechanism wherein the multimeric states of both Mff and Drp1 (show CRMP1 Proteins) regulate their collaborative interaction.

  6. Ablating Mfn1 (show MFN1 Proteins) eliminates the cardiac-related lethality of Mff knockout mice.

  7. Mitochondrial fission factor has been identified as a new AMPK (show PRKAA1 Proteins) substrate.

  8. This study reveals a novel model of mitochondrial fission regulation, which is composed of miR (show MLXIP Proteins)-761 and mitochondrial fission factor

  9. MiD49 (show SMCR7 Proteins) and MiD51 (show SMCR7L Proteins) can act independently of Mff and Fis1 (show FIS1 Proteins) in Drp1 (show CRMP1 Proteins) recruitment and suggest that they provide specificity to the division of mitochondria.

  10. immunofluorescence analysis of Drp1 (show CRMP1 Proteins) suggests that Fis1 (show FIS1 Proteins) and Mff are important for the number and size of Drp1 (show CRMP1 Proteins) puncta on mitochondria.

Mitochondrial Fission Factor (MFF) Protein Profile

Protein Summary

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MFF

  • mitochondrial fission factor (mff)
  • mitochondrial fission factor L homeolog (mff.L)
  • mitochondrial fission factor S homeolog (mff.S)
  • mitochondrial fission factor (MFF)
  • mitochondrial fission factor (Mff)
  • 5230400G24Rik protein
  • AI314724 protein
  • C2H2orf33 protein
  • C2orf33 protein
  • GL004 protein
  • mff protein
  • MGC79121 protein
  • MGC80099 protein
  • RGD1310230 protein
  • zgc:66022 protein

Protein level used designations for MFF

mitochondrial fission factor homolog B , mitochondrial fission factor homolog A , mitochondrial fission factor , Uncharacterized protein C2orf33 homolog

GENE ID SPECIES
393508 Danio rerio
443869 Xenopus laevis
446760 Xenopus laevis
459989 Pan troglodytes
708489 Macaca mulatta
100056853 Equus caballus
100328889 Oryctolagus cuniculus
100379850 Xenopus (Silurana) tropicalis
100414285 Callithrix jacchus
100579991 Nomascus leucogenys
424796 Gallus gallus
56947 Homo sapiens
506291 Bos taurus
75734 Mus musculus
301563 Rattus norvegicus
100513442 Sus scrofa
100173373 Pongo abelii
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