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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion.
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Human Polyclonal MRPS7 Primary Antibody for ICC, IF - ABIN4335610
Sotgia, Whitaker-Menezes, Martinez-Outschoorn, Salem, Tsirigos, Lamb, Sneddon, Hulit, Howell, Lisanti: Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. in Cell cycle (Georgetown, Tex.) 2012
Study identified MRPS7 mutation as a novel cause of congenital sensorineural deafness and progressive hepatic and renal failure.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.
, 28S ribosomal protein S7, mitochondrial
, ribosomal protein, mitochondrial, S7
, 30S ribosomal protein S7 homolog
, mitchondrial ribosomal protein S7