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The transcript produced from MTPN is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. Additionally we are shipping Myotrophin Kits (23) and Myotrophin Proteins (17) and many more products for this protein.
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Cow (Bovine) Polyclonal MTPN Primary Antibody for WB - ABIN2785128
Xiong, Liu, Yan, Silver, Yang, Chen, Chen, Verstovsek, Wang, Prchal, Yang: An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 2 Pubmed References
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
, granule cell differentiation protein
, protein V-1
, V-1 protein
, growth factor
, stimulates myocyte growth
, V1 protein homologue