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Inhibitor of the E3 ubiquitin-protein ligase ITCH. Additionally we are shipping and many more products for this protein.
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The p34 interacts with the WW1 domain of NEDD4-1, an interaction that enhances NEDD4-1 stability.
N4BP1 can be conjugated with SUMO1 and that this abrogates N4BP1 ubiquitylation.
May have a role in regulating tumor progression and the response of cancer cells to chemotherapy.
Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).
NEDD4-binding protein 1