Neuronal PAS Domain Protein 4 (NPAS4) ELISA Kits

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008].. Additionally we are shipping NPAS4 Antibodies (94) and NPAS4 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NPAS4 225872 Q8BGD7
Anti-Rat NPAS4 NPAS4 266734 Q8CJH6
Anti-Human NPAS4 NPAS4 266743 Q8IUM7
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Top NPAS4 ELISA Kits at antibodies-online.com

Showing 1 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Mouse 0.125 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$757.89
Details

More ELISA Kits for NPAS4 Interaction Partners

Mouse (Murine) Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. Npas4 is a critical regulator of experience-dependent, functional plasticity at mossy fiber-CA3 pyramidal synapses during contextual memory formation.

  2. the present results suggest that Npas4 controls neuronal homeostatic scaling during epileptogenesis through the induction of Homer1a as negative feedback machinery for the management of epilepsy

  3. NPAS4 is critical for the coordination of metabolism during the stimulation of electrically excitable cells; its loss leads to the defects in cellular metabolism that underlie the cellular dysfunction that occurs in metabolic disease.

  4. NPAS4 is an important regulator of plasticity mediated by endogenous cannabinoids.

  5. Results suggest that Npas4 mediates susceptibility to adolescent stress and subsequent cognitive functioning and inhibitory tone in adulthood. This shows a novel gene by environment interaction related to resilience vs vulnerability to stress, with implications for adolescent onset disorders like schizophrenia.

  6. ectopic expression of miR-744 and miR-224 during neural differentiation resulted in downregulation of endogenous Npas4 expression.

  7. Using a series of behavioral, molecular, pharmacological and genetic approaches in mice, study shows that deficiency in Npas4 affects adolescent expression of multiple markers of GABAergic transmission in the PFC, including parvalbumin and GAD67, in a sex-specific manner. Abnormal pattern of expression of GABAergic markers is associated with sex-specific and age-dependent cognitive and emotional impairments.

  8. The findings of this study suggest that Npas4 may be involved in post-stroke psychiatric changes related to anxiety ad sociability.

  9. NPAS4 is expressed in endothelial cells, regulates VE-cadherin expression and regulates sprouting angiogenesis.

  10. These findings suggest that 11beta-HSD1 may contribute to the decline in Npas4 and Arc mRNA levels associated with memory impairment during ageing

  11. beta cell cytotoxicity of the calcineurin inhibitor and immunosuppressant tacrolimus (FK-506) was prevented by Npas4 overexpression.

  12. Results suggest that transcription of the Npas4 gene is downregulated by stress through DNA methylation of its promoter

  13. induction of Npas4 identifies the area influenced by cortical spreading depression propagation.

  14. Cortex activation by sensory conditioning was found to upregulate the expression of both Npas4 and c-Fos.

  15. Data showed that differential levels of Npas4 expression in the brain may regulate anxiety, depression and cognition related disorders.

  16. Npas4 regulates Mdm2 expression during dendritic spine development in newborn olfactory bulb after sensory experience.

  17. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain

  18. Study describes a transcriptional program that is induced by neuronal activity in inhibitory neurons; while neuronal activity induces expression of early-response transcription factors such as Npas4 in both excitatory and inhibitory neurons, Npas4 activates distinct programs of late-response genes in inhibitory and excitatory neurons.

  19. Our results reveal REST and microRNA dependent mechanisms that restrict NPAS4 expression to the brain

  20. sensory stimuli, by inducing NPAS4 and its target genes, differentially control spatial features of neuronal inhibition in a way that restricts the output of the neuron while creating a dendritic environment that is permissive for plasticity

Human Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin expression and regulates sprouting angiogenesis.

  2. This review summarizes the current knowledge of the roles that Npas4 may play in neuroinflammation and ischemia. [review]

  3. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain

  4. These results provide insight into the mechanisms of NPAS4/ARNT dimerisation and transcriptional activation.

  5. a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 in the mental retardation of Down's syndrome

Zebrafish Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin expression and regulates sprouting angiogenesis.

NPAS4 Antigen Profile

Antigen Summary

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004

Gene names and symbols associated with NPAS4

  • neuronal PAS domain protein 4 (Npas4) antibody
  • neuronal PAS domain protein 4 (NPAS4) antibody
  • neuronal PAS domain protein 4a (npas4a) antibody
  • neuronal PAS domain protein 4 (npas4) antibody
  • neuronal PAS domain-containing protein 4 (Tsp_02837) antibody
  • bHLHe79 antibody
  • Le-PAS antibody
  • MGC146621 antibody
  • npas4 antibody
  • NXF antibody
  • PASD10 antibody
  • wu:fj52d04 antibody
  • zgc:136764 antibody

Protein level used designations for NPAS4

HLH-PAS transcription factor NXF , bHLH-PAS type transcription factor NXF , limbic-enhanced PAS protein , neuronal PAS domain-containing protein 4 , neuronal PAS4 , bHLH PAS type transcription factor NXF , PAS domain-containing protein 10 , class E basic helix-loop-helix protein 79 , neuronal PAS domain protein 4 , neuronal PAS domain-containing protein 4-like

GENE ID SPECIES
225872 Mus musculus
266734 Rattus norvegicus
266743 Homo sapiens
466676 Pan troglodytes
483711 Canis lupus familiaris
714161 Macaca mulatta
724016 Danio rerio
780368 Xenopus (Silurana) tropicalis
781497 Bos taurus
10899621 Trichinella spiralis
100029618 Monodelphis domestica
100052469 Equus caballus
100359105 Oryctolagus cuniculus
100397060 Callithrix jacchus
100442686 Pongo abelii
100481488 Ailuropoda melanoleuca
100520174 Sus scrofa
100593820 Nomascus leucogenys
100715310 Cavia porcellus
101113970 Ovis aries
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