anti-Nicotinamide N-Methyltransferase (NNMT) Antibodies

N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. Additionally we are shipping NNMT Kits (19) and NNMT Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NNMT 4837 P40261
NNMT 18113 O55239
NNMT 300691  
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Top anti-NNMT Antibodies at antibodies-online.com

Showing 10 out of 128 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-NNMT Antibody Titration: 2.5ug/ml Positive Control: HepG2 cell lysate Host: Rabbit Target Name: NNMT Sample Tissue: Human Hela Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Dog Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$265.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of NNMT (arrow) using rabbit polyclonal NNMT Antibody (Center)(ABIN387867). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the NNMT gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with NNMT antibody (Center) (ABIN387867), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC (p), WB NNMT Antibody (Center) (ABIN657697) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the NNMT antibody detected the NNMT protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Mouse Un-conjugated FACS, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: NNMT Antibody (3D8) [NBP2-00537] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-NNMT mouse monoclonal antibody. Immunocytochemistry/Immunofluorescence: NNMT Antibody (3D8) [NBP2-00537] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY NNMT. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Hela Cells; Lane2: Human A549 Cells; Lane3: Human U2OS Cells. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NNMT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NNMT. Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-NNMT mouse monoclonal antibody. (ABIN2454303) 0.1 mL Log in to see Available
$451.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-NNMT mouse monoclonal antibody (ABIN2454313) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NNMT (RC200641). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NNMT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NNMT. 0.1 mL Log in to see Available
$451.00
Details

NNMT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-NNMT Antibodies

  1. Human Monoclonal NNMT Primary Antibody for FACS, ICC - ABIN4339635 : Chen, Wang, Huang, Yong, Shen, Tang, Zhu, Ni, Feng: Nicotinamide N-methyltransferase: a potential biomarker for worse prognosis in gastric carcinoma. in American journal of cancer research 2016 (PubMed)
    Show all 2 Pubmed References

  2. Dog (Canine) Polyclonal NNMT Primary Antibody for WB - ABIN2775335 : Roessler, Rollinger, Palme, Hagmann, Berndt, Engel, Schneidinger, Pfeffer, Andres, Karl, Bodenmüller, Rüschoff, Henkel, Rohr, Rossol, Rösch, Langen, Zolg, Tacke: Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)
    Show all 2 Pubmed References

More Antibodies against NNMT Interaction Partners

Human Nicotinamide N-Methyltransferase (NNMT) interaction partners

  1. Here we explored the association between NNMT gene polymorphisms and obesity. The subjects were recruited from male Chinese Han college student... the variation of the tagSNP, rs10891644, is significantly associated with obesity and the GT carriers are the susceptible population

  2. our results suggest that the ZEB1 (show ZEB1 Antibodies)/NNMT signaling axis induces phenotypic and metabolic plasticity, as well as mesenchymal gene expression in ovarian cancer cells upon chronic glucose deprivation

  3. We demonstrate that NNMT outcompetes leucine carboxyl methyl transferase 1 (LCMT1) for methyl transfer from principal methyl donor SAM in biological systems. Inhibiting NNMT increased the availability of methyl groups for LCMT1 to methylate PP2A, resulting in the inhibition of oncogenic serine/threonine kinases (STK).

  4. High expression level of NNMT is associated with pancreatic cancer.

  5. This finding, for the first time, suggests the involvement of the NNMT gene rs694539 variant in the etiology of epilepsy.

  6. this study provides the first demonstration that NNMT plays a role in the resistance to 5-fluorouracil in colorectal cancer cells

  7. We suggest that lymph node metastatic adenoid cystic carcinoma (AdCC) cells acquire cancer stem cell features involving the up-regulation of NNMT and the loss of gap junction protein alpha-1 (show GJA1 Antibodies), leading to epithelial-mesenchymal transition and consequent AdCC metastasis.

  8. Progression of pulmonary hypertension is associated with the activation of the NNMT-1-methylnicotinamide pathway.

  9. no SNP in NNMT is significantly associated with performance in 50-m run but rs2256292 is significantly associated with performance in 1000-m run in male Chinese college students

  10. These findings indicate that the repression of NNMT may underlie nickel-induced H3K9 dimethylation by altering the cellular SAM (show TTN Antibodies)/SAH (show ACSM3 Antibodies) ratio.

Mouse (Murine) Nicotinamide N-Methyltransferase (NNMT) interaction partners

  1. Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide have been presented.

  2. NNMT is a novel regulator of histone methylation, polyamine flux and NAD(+)-dependent SIRT1 (show SIRT1 Antibodies) signalling, and is a unique and attractive target for treating obesity and type 2 diabetes

  3. Brain NNMT expression was not altered in hyperhomocysteinemia.

  4. Adipose tissue is a source of nicotinamide N-methyltransferase and homocysteine.

  5. the progression of vascular inflammation and atherosclerosis was associated with the upregulation of hepatic nicotinamide N-methyltransferase activity and subsequent increase in endogenous MNA plasma levels

NNMT Antigen Profile

Protein Summary

N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.

Gene names and symbols associated with NNMT

  • nicotinamide N-methyltransferase S homeolog (nnmt.S) antibody
  • nicotinamide N-methyltransferase (CNG02680) antibody
  • nicotinamide N-methyltransferase (AFUA_1G17750) antibody
  • nicotinamide N-methyltransferase (AOR_1_1132194) antibody
  • nicotinamide N-methyltransferase (AOR_1_1124014) antibody
  • nicotinamide N-methyltransferase (CC1G_02598) antibody
  • nicotinamide n-methyltransferase (VDBG_08111) antibody
  • nicotinamide N-methyltransferase (TERG_00572) antibody
  • nicotinamide N-methyltransferase (Tsp_04293) antibody
  • Nicotinamide N-methyltransferase (nnmt) antibody
  • nicotinamide N-methyltransferase (NNMT) antibody
  • nicotinamide N-methyltransferase (Nnmt) antibody
  • Afu1g17750 antibody
  • AO090026000620 antibody
  • MGC64498 antibody
  • nnmt antibody

Protein level used designations for NNMT

nicotinamide N-methyltransferase , nicotinamide n-methyltransferase , Nicotinamide N-methyltransferase

GENE ID SPECIES
379432 Xenopus laevis
3258655 Cryptococcus neoformans var. neoformans JEC21
3510174 Aspergillus fumigatus Af293
5988105 Aspergillus oryzae RIB40
5994073 Aspergillus oryzae RIB40
6016766 Coprinopsis cinerea okayama7130
9529830 Verticillium alfalfae VaMs.102
10374048 Trichophyton rubrum CBS 118892
10905204 Trichinella spiralis
100286563 Salmo salar
4837 Homo sapiens
489396 Canis lupus familiaris
100144485 Sus scrofa
18113 Mus musculus
300691 Rattus norvegicus
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