anti-Nucleobindin 1 (NUCB1) Antibodies

NUCB1 encodes a member of a small calcium-binding EF-hand protein family. Additionally we are shipping Nucleobindin 1 Kits (17) and Nucleobindin 1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NUCB1 18220 Q02819
NUCB1 84595 Q63083
NUCB1 4924 Q02818
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Top anti-Nucleobindin 1 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NUCB1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$319.00
Details
Dog Rabbit Un-conjugated IHC WB Suggested Anti-NUCB1 Antibody Titration:  5.0ug/ml  Positive Control:  Hela cell lysate Rat NRK 100 μL 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Rat Kidney lysate; Primary Ab: 1µg/ml Rabbit Anti-Mouse NUCB1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg 13 to 16 Days
$360.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with NUCB1 antibody ABIN214130 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with NUCB1 antibody ABIN214130 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 100 μL 11 to 14 Days
$727.83
Details
Dog Rabbit Un-conjugated IHC, WB 100 μL 11 to 14 Days
$493.17
Details
Human Mouse Un-conjugated IF, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-NUCB1 mouse monoclonal antibody (ABIN2455386) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NUCB1 (RC201786). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NUCB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NUCB1. 0.1 mL 2 to 3 Days
$462.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB HEK293T cells transfected with either RC201786 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-NUCB1 antibody (ABIN2455248), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NUCB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NUCB1. 0.1 mL 2 to 3 Days
$462.00
Details

Top referenced anti-Nucleobindin 1 Antibodies

  1. Human Polyclonal Nucleobindin 1 Primary Antibody for WB - ABIN2792698 : de Alba, Tjandra: Structural studies on the Ca2+-binding domain of human nucleobindin (calnuc). in Biochemistry 2004 (PubMed)
    Show all 7 Pubmed References

  2. Dog (Canine) Polyclonal Nucleobindin 1 Primary Antibody for IHC - ABIN2792697 : Wendel, Sommarin, Bergman, Heinegård: Isolation, characterization, and primary structure of a calcium-binding 63-kDa bone protein. in The Journal of biological chemistry 1995 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal Nucleobindin 1 Primary Antibody for WB - ABIN2792699 : Larkin, Costantino, Seaman, Lavoie: Calnuc Function in Endosomal Sorting of Lysosomal Receptors. in Traffic (Copenhagen, Denmark) 2016 (PubMed)

More Antibodies against Nucleobindin 1 Interaction Partners

Mouse (Murine) Nucleobindin 1 (NUCB1) interaction partners

  1. The chaperone protein Hsp70 was found to be important for CHIP and NUCB1 interaction as well as CHIP-mediated NUCB1 down-regulation.

  2. the expression and distribution of NUCB1 in tissues and cells of the mouse endocrine system, was examined.

  3. This protein is stored and processed in the Golgi and secreted by the constitutive-like pathway in AtT20 cells.

Human Nucleobindin 1 (NUCB1) interaction partners

  1. Data suggest that calnuc (nucleobindin 1) is possibly involved in controlling protein unfolding diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), prion disease, and type II diabetes.

  2. Calnuc depletion causes the misdelivery to and degradation in lysosomes of cationic-independent mannose-6-phosphate receptor and Sortilin .

  3. nesfatin-1 has a role in thyroid dysfunction in patients with T2DM

  4. The serine protease activity of calnuc is allosterically regulated by Zn2+ binding and its interaction with G protein alpha subunit.

  5. postulate that the engineered forms of NUCB1 prevent hIAPP fibril formation by a mechanism where protofibril-like species are "capped" to prevent further fibril assembly and maturation

  6. structural basis for the properties of Calnuc and NUCB2 binding to Galpha subunits and its regulation by calcium ions.

  7. Nucleobindin 1 is a calcium-regulated guanine nucleotide dissociation inhibitor of G{alpha}i1.

  8. Comparison between the structure of nucleobindin and other EF-hand proteins sheds light into the dual function of nucleobindin as Ca2+ storage (buffer) and Ca2+ sensor.

  9. Calnuc protein may be a tumor-associated antigen (TAA) that induces autoantibody response in human cancers

  10. NUCB1 is the first-identified, Golgi-localized negative feedback regulator in the ATF6-mediated branch of the UPR

  11. results suggest that the functions of nucleobindins could be modulated by caspase-mediated cleavage in apoptosis

  12. Proline residue at the +2-position (Pro(+2)) from the signal peptide cleavage site is the determinant of NUCB1 protein export from the ER and subsequent transport to the Golgi.

Nucleobindin 1 (NUCB1) Antigen Profile

Protein Summary

This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events.

Gene names and symbols associated with anti-Nucleobindin 1 (NUCB1) Antibodies

  • nucleobindin 1 (nucb1) antibody
  • nucleobindin 1 S homeolog (nucb1.S) antibody
  • nucleobindin 1 (NUCB1) antibody
  • nucleobindin 1 (Nucb1) antibody
  • B230337F23Rik antibody
  • C77483 antibody
  • CALNUC antibody
  • DKFZp459O1814 antibody
  • MGC69294 antibody
  • MGC81496 antibody
  • MTEST82 antibody
  • NUC antibody
  • Nucb antibody
  • NUCB1 antibody
  • zgc:153192 antibody

Protein level used designations for anti-Nucleobindin 1 (NUCB1) Antibodies

nucleobindin 1 , nucleobindin-1 , Nucleobindin-1 , nucleobindin-1-like , CALNUC , bone 63 kDa calcium-binding protein

GENE ID SPECIES
407884 Xenopus (Silurana) tropicalis
414482 Xenopus laevis
456193 Pan troglodytes
751753 Danio rerio
100173912 Pongo abelii
100406205 Callithrix jacchus
484391 Canis lupus familiaris
18220 Mus musculus
84595 Rattus norvegicus
4924 Homo sapiens
505351 Bos taurus
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