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PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2 (MAD2L1; MIM 601467) (Nakaya et al., 2010. Additionally we are shipping PCI Domain Containing 2 Proteins (8) and PCI Domain Containing 2 Kits (5) and many more products for this protein.
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Data show that PCI domain-containing protein 2 (Pcid2) controls lymphoid lineage commitment through the regulation of Snf2-related CREBBP activator protein (SRCAP) remodelling activity.
Pcid2 is present in the CBP/p300-EID1 complex to control the switch balance of mouse and human embryonic stem cells through modulation of EID1 degradation.
First discovery of specific novel functions for PCID2 other than mRNA export and components of the TREX-2 complex serve alternative shared roles in the regulation of nuclear transport and cell cycle progression.
validated occurrence of an unusual TG 3' splice site in intron 2
Pcid2 is essential for B cell survival through the regulation of MAD2 expression during B cell differentiation
PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2 (MAD2L1\; MIM 601467) (Nakaya et al., 2010
, PCI domain-containing protein 2
, uncharacterized protein LOC361182