PDZ Domain Containing 3 Proteins

Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E.

Data Quality
  • 3
Type
  • 3
    Protein
Antigen
  • 3
Reactivity
  • 2
  • 1
Application
  • 3
  • 3
  • 2
  • 2
  • 1
Host
  • 2
  • 1
Binding Specificity
  • 1
  • 1
  • 1
Conjugate
  • 2
  • 1
Protein Type
  • 3
Format
  • 2
3 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3128056
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3084313
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1314608
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
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PDZ Domain Containing 3 (PDZD3) Protein Profile

Protein Summary

Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002

Gene names and symbols associated with PDZD3

  • PDZ domain containing 3 (Pdzd3) antibody
  • PDZ domain containing 3b (pdzd3b) antibody
  • PDZ domain containing 3 (PDZD3) antibody
  • IKEPP antibody
  • NaPi-Cap2 antibody
  • NHERF4 antibody
  • Pdzk2 antibody
  • RGD1559807 antibody
  • zgc:194812 antibody

Protein level used designations for PDZD3

Na(+)/H(+) exchange regulatory cofactor NHE-RF4 , PDZ domain containing 3 , NHERF-4 , PDZ domain containing 2 , PDZ domain-containing protein 2 , PDZ domain-containing protein 3 , intestinal and kidney enriched PDZ protein , intestinal and kidney-enriched PDZ protein , na/Pi cotransporter C-terminal-associated protein 2 , naPi-Cap2 , natrium-phosphate cotransporter IIa C-terminal-associated protein 2 , sodium-hydrogen exchanger regulatory factor 4 , sodium-phosphate cotransporter IIa C-terminal-associated protein 2

GENE ID SPECIES
500986 Rattus norvegicus
566852 Danio rerio
79849 Homo sapiens
170761 Mus musculus
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