PDZ Domain Containing 3 Proteins
Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E.
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PDZ Domain Containing 3 (PDZD3) (AA 1-571) protein (His tag) Protein
PDZ Domain Containing 3 (PDZD3) (AA 1-498) protein (His tag) Protein
PDZ Domain Containing 3 (PDZD3) (AA 1-491) protein (GST tag) Protein
PDZ Domain Containing 3 (PDZD3) Protein Profile
Protein Summary
Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002
Gene names and symbols associated with PDZD3
- PDZ domain containing 3 (Pdzd3) antibody
- PDZ domain containing 3b (pdzd3b) antibody
- PDZ domain containing 3 (PDZD3) antibody
- IKEPP antibody
- NaPi-Cap2 antibody
- NHERF4 antibody
- Pdzk2 antibody
- RGD1559807 antibody
- zgc:194812 antibody
Protein level used designations for PDZD3
Na(+)/H(+) exchange regulatory cofactor NHE-RF4 , PDZ domain containing 3 , NHERF-4 , PDZ domain containing 2 , PDZ domain-containing protein 2 , PDZ domain-containing protein 3 , intestinal and kidney enriched PDZ protein , intestinal and kidney-enriched PDZ protein , na/Pi cotransporter C-terminal-associated protein 2 , naPi-Cap2 , natrium-phosphate cotransporter IIa C-terminal-associated protein 2 , sodium-hydrogen exchanger regulatory factor 4 , sodium-phosphate cotransporter IIa C-terminal-associated protein 2
GENE ID | SPECIES |
---|---|
500986 | Rattus norvegicus |
566852 | Danio rerio |
79849 | Homo sapiens |
170761 | Mus musculus |
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