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Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. Additionally we are shipping PDZ Domain Containing 3 Antibodies (45) and PDZ Domain Containing 3 Kits (1) and many more products for this protein.
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Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002
Na(+)/H(+) exchange regulatory cofactor NHE-RF4
, PDZ domain containing 3
, PDZ domain containing 2
, PDZ domain-containing protein 2
, PDZ domain-containing protein 3
, intestinal and kidney enriched PDZ protein
, intestinal and kidney-enriched PDZ protein
, na/Pi cotransporter C-terminal-associated protein 2
, natrium-phosphate cotransporter IIa C-terminal-associated protein 2
, sodium-hydrogen exchanger regulatory factor 4
, sodium-phosphate cotransporter IIa C-terminal-associated protein 2