POC1 Centriolar Protein Homolog B (Chlamydomonas) Proteins (POC1B)

Required for ciliogenesis (By similarity).. Additionally we are shipping POC1B Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
POC1B 282809 Q8TC44
POC1B 382406 Q8BHD1
POC1B    
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Top POC1B Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
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Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$3,386.17
Details

POC1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Zebrafish (Danio rerio)

More Proteins for POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) Interaction Partners

Human POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) interaction partners

  1. Depletion of CEP295 blocks the incorporation of POC5 (show POC5 Proteins) and POC1B into the distal portion of centrioles and suppresses the post-translational modification of centriolar microtubules . Our study thus uncovers a new role for CEP295 during centriole elongation.

  2. Intronic SNP in POC1B/GALNT4 (show GALNT4 Proteins) locus (rs11105306) was associated with NT-proBNP levels in patients with acute coronary syndrome (ACS (show PLA2G15 Proteins)). The POC1B/GALNT4 (show GALNT4 Proteins) SNP was not associated with higher risk of cardiovascular death.

  3. Study found that homozygous POC1B mutation, i.e., c.737C --> T(p.T246 M), cosegregated with the phenotype of a tested family, indicating that POC1B gene was the most possible pathogenic gene for paroxysmal kinesigenic dyskinesia

  4. Study indicates that POC1B is required for retinal integrity, and is proposed POC1B mutations as a probable cause for Joubert syndrome with severe polycystic kidney disease.

  5. POC1B is a novel gene for a new disease typical of cone-rod dystrophy except that patients did not report night blindness.

  6. POC1B mutations result in a defect of the photoreceptor sensory cilium and thus affect cone and rod photoreceptors.

  7. Poc1A (show POC1A Proteins) and Poc1B play redundant, but essential, roles in generation of stable centrioles, but Poc1B may have additional independent functions during cell cycle progression.

  8. Poc1B is required for primary ciliogenesis; Poc1 provides a molecular link between the assembly and stability of centrioles for ciliary-based motility in T. thermophila and cilia formation and function in zebrafish and humans

  9. Based on these data, we propose that Pix1 and Pix2 (show POC1A Proteins) are microtubule-associated adaptor proteins that likely contribute to a range of developmental and cell division processes.

Zebrafish POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) interaction partners

  1. data suggest that poc1b is required for normal development and ciliogenesis of retinal photoreceptor sensory cilia and other cilia

  2. Poc1B knockdown causes ciliary defects & morphological phenotype consistent with ciliopathies; Poc1 provides link between assembly & stability of centrioles for ciliary-based motility in Tetrahymena & cilia formation & function in D rerio & humans

POC1B Protein Profile

Protein Summary

Required for ciliogenesis (By similarity).

Gene names and symbols associated with POC1B

  • POC1 centriolar protein B (POC1B)
  • POC1 centriolar protein B (Poc1b)
  • POC1 centriolar protein B (poc1b)
  • 4933430F16Rik protein
  • fl36w17 protein
  • PIX1 protein
  • TUWD12 protein
  • wdr51b protein
  • wu:fl36w17 protein
  • zgc:63538 protein

Protein level used designations for POC1B

POC1 centriolar protein homolog B , WD repeat-containing protein 51B , WD repeat domain 51B

GENE ID SPECIES
282809 Homo sapiens
382406 Mus musculus
386932 Danio rerio
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