Paternally Expressed 10 Proteins
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift.
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Paternally Expressed 10 (PEG10) (AA 1-708) protein (His tag) Protein
Paternally Expressed 10 (PEG10) (AA 1-958) protein (His tag) Protein
Paternally Expressed 10 (PEG10) (AA 1-325) protein (GST tag) Protein
Paternally Expressed 10 (PEG10) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
Paternally Expressed 10 (PEG10) Protein Profile
Protein Summary
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
Gene names and symbols associated with PEG10
- paternally expressed 10 (PEG10) antibody
- paternally expressed 10 (Peg10) antibody
- AA407948 antibody
- Edr antibody
- HB-1 antibody
- Mar2 antibody
- Mart2 antibody
- MEF3L antibody
- MyEF-3 antibody
- RGAG3 antibody
Protein level used designations for PEG10
MEF3 like 1 , MEF3-like protein 1 , embryonal carcinoma differentiation regulated , embryonal carcinoma differentiation-regulated protein , mammalian retrotransposon-derived protein 2 , myelin expression factor 3-like protein 1 , paternally expressed gene 10 protein , retrotransposon gag domain containing 3 , retrotransposon gag domain-containing protein 3 , retrotransposon-derived gag-like polyprotein , retrotransposon-derived protein PEG10 , ty3/Gypsy-like protein , MyEF-3 like , embryonal carcinoma differentiation regulated protein , myelin expression factor 3 , paternally expressed 10 , LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10 , retrotransposon-derived protein PEG10-like
GENE ID | SPECIES |
---|---|
23089 | Homo sapiens |
170676 | Mus musculus |
472446 | Pan troglodytes |
482307 | Canis lupus familiaris |
618138 | Bos taurus |
654416 | Sus scrofa |
700853 | Macaca mulatta |
100062501 | Equus caballus |
100359412 | Ovis aries |
102553587 | Rattus norvegicus |
100352080 | Oryctolagus cuniculus |
100720271 | Cavia porcellus |
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