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PGC encodes an aspartic proteinase that belongs to the peptidase family A1. Additionally we are shipping PGC Kits (59) and PGC Proteins (25) and many more products for this protein.
Showing 10 out of 177 products:
Human Monoclonal PGC Primary Antibody for ELISA - ABIN2476102
Kawamura, Kawashima, Fukunaga, Hirai, Toyama-Sorimachi, Tokuhara, Shimizu, Dohi: Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis. in Cancer research 2005
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
, pepsinogen C
, pepsin C
, pepsinogen group II
, urinary pepsinogen 1
, Urinary pepsinogen 1