anti-Periostin, Osteoblast Specific Factor (POSTN) Antibodies

Binds to heparin. Additionally we are shipping POSTN Kits (75) and POSTN Proteins (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POSTN 10631 Q15063
POSTN 50706 Q62009
POSTN 361945  
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Top anti-POSTN Antibodies at

Showing 10 out of 204 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-POSTN antibody (ARP41570_P050) 100 μL 2 to 3 Days
Human Goat Un-conjugated ELISA, WB ABIN1590102 (2 µg/mL) staining of MCF7 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
Mouse Rabbit Un-conjugated ELISA, IHC (p), WB Western blot analysis of Periostin using anti-Periostin antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: rat gaster tissue lysates,  Lane 2: rat lung tissue lysates, Lane 3: rat NRK whole cell lysates, Lane 4: mouse gaster tissue lysates, Lane 5: mouse intestine tissue lysates, Lane 6: mouse lung tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Periostin antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Periostin at approximately 93KD. The expected band size for Periostin is at 93KD. IHC analysis of Periostin using anti-Periostin antibody .Periostin was detected in paraffin-embedded section of mouse gaster tissue . Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-Periostin Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg 4 to 6 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric tissue, using Periostin, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Periostin, antibody at 1:200 dilution. 100 μL 3 to 4 Days
Mouse Rabbit Un-conjugated WB Anti- Periostin antibody,  Western blotting All lanes: Anti Periostin () at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3: SKOV Whole Cell Lysate at 40ug Predicted bind size: 93KD Observed bind size: 93KD Anti- Periostin antibody, Western blotting All lanes: Anti Periostin  at 0.5ug/ml WB: Mouse Cardiac Muscle Tissue Lysate at 50ug Predicted bind size: 93KD Observed bind size: 93KD 100 μg 4 to 6 Days
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of Periostin Antibody (C-term) Cat.-No AP53392PU-N with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Formalin fixed and paraffin embedded human uterus tissue reacted with Periostin Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL 6 to 8 Days
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
Human Mouse Un-conjugated IF, WB Periostin antibody (47) at 1:500 dilution + lysate from HeLa cells transfected with human periostin gene expression vector 0.1 mL 2 to 3 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Human Serum. 100 μg 15 to 18 Days

Top referenced anti-POSTN Antibodies

  1. Chicken Polyclonal POSTN Primary Antibody for ICC, IF - ABIN447454 : Lorts, Schwanekamp, Baudino, McNally, Molkentin: Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-β pathway. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 17 Pubmed References

  2. Human Monoclonal POSTN Primary Antibody for IHC, WB - ABIN2728671 : Lai, Chen: Identification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma. in Proteomics 2015 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal POSTN Primary Antibody for IHC, IHC (p) - ABIN4344896 : Gbormittah, Haab, Partyka, Garcia-Ott, Hancapie, Hancock: Characterization of glycoproteins in pancreatic cyst fluid using a high-performance multiple lectin affinity chromatography platform. in Journal of proteome research 2014 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal POSTN Primary Antibody for IHC, ELISA - ABIN1169103 : Wang, Liu, Wang, Huang, Liu, Zhu, Cai, Fang, Lin, Yuan, Ouyang: Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells. in PLoS ONE 2013 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal POSTN Primary Antibody for ICC, IF - ABIN4344892 : Ratajczak-Wielgomas, Gosk, Rabczyński, Augoff, Podhorska-Okołów, Gamian, Rutowski: Expression of MMP-2, TIMP-2, TGF-β1, and decorin in Dupuytren's contracture. in Connective tissue research 2012 (PubMed)

  6. Human Polyclonal POSTN Primary Antibody for IHC, IHC (p) - ABIN4892111 : Ratajczak-Wielgomas, Grzegrzolka, Piotrowska, Matkowski, Wojnar, Rys, Ugorski, Dziegiel: Expression of periostin in breast cancer cells. in International journal of oncology 1970 (PubMed)

  7. Human Monoclonal POSTN Primary Antibody for IF, WB - ABIN2728665 : Itaya, Oka, Ogata, Tamura, Kira-Tatsuoka, Fujiwara, Otsu, Tsuruga, Ozaki, Harada: Hertwig's epithelial root sheath cells contribute to formation of periodontal ligament through epithelial-mesenchymal transition by TGF-β. in Biomedical research (Tokyo, Japan) 2017 (PubMed)

More Antibodies against POSTN Interaction Partners

Human Periostin, Osteoblast Specific Factor (POSTN) interaction partners

  1. Thus, periostin level seems to be a strongly related factor for asthma and allergic rhinitis after 5 years of age, since the predicted medians in both subclinical and clinical allergy children were higher than those in non-allergic children.

  2. In our sample of children with uncontrolled asthma, serum periostin levels did not discriminate between severe and nonserious asthma.

  3. Activated hepatic stellate cells promote the tumor progression of heat-treated residual hepatocellular carcinoma through the release of POSTN.

  4. POSTN total immunoreactive score on prostate cancer biopsy samples independently predicted the risk of recurrence, progression, and death in patients with localized disease and in those with low to intermediate Gleason scores.

  5. revascularization and progression of pancreatic neuroendocrine tumors (PNETs) under extended vascular-endothelial growth factor A (VEGFA) blockade are dependent on periostin (POSTN), a matricellular protein expressed by stromal cells.

  6. Our results show that s-periostin is elevated in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). S-periostin, s-IgE, and s-SE-IgE may be used as biomarkers to predict the expression of IL-5 or SE-IgE in nasal polyp tissue, that is, identifying patients with CRSwNP with moderate and severe type 2 inflammation.

  7. otch signaling directly regulates transcription of POSTN in hepatocytes and liver cancer cell lines and may be a candidate for drug targeting in liver cancer.

  8. the present study revealed that periostin might promote angiogenesis and eosinophil recruitment, indicating that periostin is a critical matricellular component in remodelling the tissue microenvironment in ENP.

  9. Periostin upregulates the effector functions of eosinophils.

  10. this study found no longitudinal variation of serum periostin levels in adults with stable asthma

  11. the crystal structures of human periostin (EMI-Fas1(I-)(IV) ) and its Cys60Ala mutant. In combination with multi-angle light-scattering analysis and biochemical assays, the crystal structures reveal that periostin mainly exists as a dimer in solution and its homophilic interaction is mainly mediated by the EMI domain.

  12. POSTN accelerated the migration, proliferation, and osteogenic differentiation of hPDLSCs.

  13. These results suggest that an increased periostin level may contribute to the progression of airway inflammation to remodeling in [Toluene diisocyanate ]TDI-exposed workers. A high serum periostin level is a potential serologic marker of the phenotype of TDI-OA [occupational asthma ].

  14. Integrin alphaM is a specific marker of activated tissue eosinophils in Eosinophilic esophagitis, and promotes eosinophil survival through interactions with periostin.

  15. An interaction was found between LRP5 SNP rs648438 and periostin SNP rs9547970 on serum periostin levels and on radial cortical porosity.

  16. On 10 mug/ml periostin or TGFBI, more eosinophils adopted a flattened pancake morphology with dispersed granules and nuclear lobes, and slower migration. Conversion between acorn and pancake morphologies were observed. TGFBI or periostin supports two modes of migration by IL-5 family cytokine-activated eosinophils.

  17. Authors found that the antioxidant cinnamaldehyde activated the NRF2/HMOX1 pathway. Cinnamaldehyde also alleviated TGF-beta1- and IL-13-mediated production of reactive oxygen species and subsequent POSTN upregulation in dermal fibroblasts. NRF2 silencing abolished the cinnamaldehyde-mediated downregulation of POSTN.

  18. Periostin levels were significantly higher in patients with ameloblastoma than in controls. Moreover, Periostin levels in patients with ameloblastoma were significantly associated with the number of disease. Furthermore, the results suggested that Periostin expression significantly promoted the proliferation and migration, in addition to cell cycle progression of AM-1 cells.

  19. prominent in the superficial dermis in both pemphigus vulgaris and bullous pemphigoid lesions

  20. Findings indicate that Postn deficiency impairs liver regeneration in mice after partial hepatectomy and Postn might be a novel promoter for liver regeneration.

Mouse (Murine) Periostin, Osteoblast Specific Factor (POSTN) interaction partners

  1. marker of renal fibrosis and may augment the progression of fibrogenesis as an extracellular matrix protein

  2. revascularization and progression of pancreatic neuroendocrine tumors (PNETs) under extended vascular-endothelial growth factor A (VEGFA) blockade are dependent on periostin (POSTN), a matricellular protein expressed by stromal cells.

  3. Increased expression of Periostin promotes liver fibrogenesis by activating lysyl oxidase.

  4. Inhibition of periostin could be important for suppressing capsule formation on silicone implants after in vivo implantation.

  5. Unaffected by Postn, Vav-Itgav(-/-) haematopoietic stem cell proliferate faster in vitro, illustrating the importance of Postn-Itgav interaction.

  6. Periostin-expressing myofibroblasts in the heart derive from tissue-resident fibroblasts of the Tcf21 lineage and are necessary for adaptive healing and fibrosis.

  7. mesenchymal source, specific to cardiovascular tissues, roles in cardiovascular development and disease [review]

  8. Results indicate that periostin is a key player in the development of bleomycin-induced fibrosis and consequent enhancement of tumor cell colonization in the lung.

  9. Periostin gene deletion impairs periosteal cells functions and fracture consolidation.

  10. these data indicate that CatK not only plays a major role in bone remodeling but also modulates modeling-based cortical bone formation by degrading periostin and thereby moderating Wnt-beta-catenin signaling.

  11. Ablation of periostin suppresses post-infarction myocardial regeneration by inhibiting the PI3K/GSK3beta/cyclin D1 signalling pathway, indicating that periostin is essential for myocardial regeneration.

  12. this study shows that periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis

  13. Genetic or pharmaco-genetic inhibition of periostin in animal models of renal disease was efficient in arresting the progression of the kidney pathology. (Review)

  14. TGFBI and periostin act similarly in the heart in affecting fibrosis and disease responsiveness.

  15. Results suggest that stromal cell periostin (POSTN) supports both normal hematopoietic progenitor cells (HPCs) and leukemia-initiating cells in vitro.

  16. the expressions of the periostin splice variants were increased in ischemic retinas.

  17. POSTN regulates the scar formation after spinal cord injuries.

  18. periostin in the extracellular matrix architecture prevents pulmonary leakage of blood fluid, thus increasing the survival rate in mice with acute lung injury

  19. These results indicated that tensile stress load increased the expression levels of PN in mouse peridontal ligaments and human periodontal ligament cells.

  20. POSTN promotes the pulmonary accumulation of myeloid-derived suppressor cells (MDSCs) during the early stage of breast tumour metastasis. Postn deletion decreases neutrophil and monocytic cell populations in the bone marrow of mice and suppresses the accumulation of MDSCs to premetastatic sites.

Cow (Bovine) Periostin, Osteoblast Specific Factor (POSTN) interaction partners

  1. These results suggest that periostin is one of the local contributing factors in bone and periodontal tissue remodeling following mechanical stress during experimental tooth movement [periostin].

POSTN Antigen Profile

Protein Summary

Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.

Gene names and symbols associated with POSTN

  • periostin (POSTN) antibody
  • periostin, osteoblast specific factor b (postnb) antibody
  • periostin, osteoblast specific factor (postn) antibody
  • periostin, osteoblast specific factor (Postn) antibody
  • periostin (Postn) antibody
  • A630052E07Rik antibody
  • AI747096 antibody
  • fa99h07 antibody
  • LOC100008945 antibody
  • OSF-2 antibody
  • Osf2 antibody
  • PDLPOSTN antibody
  • peri antibody
  • periostin antibody
  • Plf antibody
  • PN antibody
  • postn antibody
  • RP11-412K4.1 antibody
  • wu:fa99h07 antibody
  • wu:fc70f09 antibody
  • zgc:153873 antibody

Protein level used designations for POSTN

periostin , periostin, osteoblast specific factor , rp11-412k4.1 , extracellular adhestion molecule , osteoblast-specific factor 2 , osteoblast specific factor 2 (fasciclin I-like) , periodontal ligament-specific periostin , periostin isoform thy2 , periostin isoform thy4 , periostin isoform thy6 , periostin isoform thy8 , periostin-like factor , periostin variant 6 , periostin variant 7 , periostin variant 8 , periostin variant 9

100062608 Equus caballus
337176 Danio rerio
100008945 Oryctolagus cuniculus
100127174 Xenopus (Silurana) tropicalis
395429 Gallus gallus
10631 Homo sapiens
50706 Mus musculus
361945 Rattus norvegicus
477298 Canis lupus familiaris
281960 Bos taurus
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