anti-Periostin, Osteoblast Specific Factor (POSTN) Antibodies

Binds to heparin. Additionally we are shipping POSTN Kits (74) and POSTN Proteins (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POSTN 10631 Q15063
POSTN 50706 Q62009
POSTN 361945  
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Top anti-POSTN Antibodies at

Showing 10 out of 197 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Chicken Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Immunohistochemistry: Periostin/OSF-2 Antibody [NBP1-30042] - Analysis of periostin in rabbit periosteum. Image courtesy of product review submitted by Samer Zaky. Western Blot: Periostin/OSF-2 Antibody [NBP1-30042] - Rat lung lysate showing specific immunolabeling of the ~ 93 kDa periostin protein doublet. 0.1 mL Log in to see 7 to 9 Days
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-POSTN antibody (ARP41570_P050) 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB ABIN1590102 (2 µg/mL) staining of MCF7 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
Mouse Rabbit Un-conjugated ELISA, IHC (p), WB Western blot analysis of Periostin using anti-Periostin antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: rat gaster tissue lysates,  Lane 2: rat lung tissue lysates, Lane 3: rat NRK whole cell lysates, Lane 4: mouse gaster tissue lysates, Lane 5: mouse intestine tissue lysates, Lane 6: mouse lung tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Periostin antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Periostin at approximately 93KD. The expected band size for Periostin is at 93KD. IHC analysis of Periostin using anti-Periostin antibody .Periostin was detected in paraffin-embedded section of mouse gaster tissue . Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-Periostin Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric tissue, using Periostin, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Periostin, antibody at 1:200 dilution. 100 μL Log in to see 3 to 4 Days
Human Rabbit Un-conjugated IF, IHC (p), WB POSTN Antibody (C-term)  western blot analysis in MCF-7(lane 1),A375(lane 2) cell line lysates (35ug/lane).This demonstrates the POSTN antibody detected the POSTN protein (arrow). POSTN Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POSTN Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
Mouse Rabbit Un-conjugated WB Anti- Periostin antibody,  Western blotting All lanes: Anti Periostin () at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3: SKOV Whole Cell Lysate at 40ug Predicted bind size: 93KD Observed bind size: 93KD Anti- Periostin antibody, Western blotting All lanes: Anti Periostin  at 0.5ug/ml WB: Mouse Cardiac Muscle Tissue Lysate at 50ug Predicted bind size: 93KD Observed bind size: 93KD 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of Periostin Antibody (C-term) Cat.-No AP53392PU-N with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Formalin fixed and paraffin embedded human uterus tissue reacted with Periostin Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Periostin/OSF-2 Antibody [NBP1-82472] - Immunohistochemical staining of human bronchus shows strong cytoplasmic positivity in respiratory epithelial cells. Immunohistochemistry-Paraffin: Periostin/OSF-2 Antibody  - Staining of human pancreas shows low expression as expected. 0.1 mL Log in to see 10 to 13 Days

Top referenced anti-POSTN Antibodies

  1. Chicken Polyclonal POSTN Primary Antibody for ICC, IF - ABIN447454 : Lorts, Schwanekamp, Baudino, McNally, Molkentin: Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-β pathway. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 13 Pubmed References

  2. Human Polyclonal POSTN Primary Antibody for IHC, IHC (p) - ABIN4344896 : Gbormittah, Haab, Partyka, Garcia-Ott, Hancapie, Hancock: Characterization of glycoproteins in pancreatic cyst fluid using a high-performance multiple lectin affinity chromatography platform. in Journal of proteome research 2014 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal POSTN Primary Antibody for IHC, ELISA - ABIN1169103 : Wang, Liu, Wang, Huang, Liu, Zhu, Cai, Fang, Lin, Yuan, Ouyang: Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells. in PLoS ONE 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal POSTN Primary Antibody for IHC, WB - ABIN2728671 : Lai, Chen: Identification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma. in Proteomics 2015 (PubMed)

  5. Human Polyclonal POSTN Primary Antibody for IF, IHC (p) - ABIN655902 : Park, Piao, Jeong, Dong, de Groot: Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models. in Molecular cancer therapeutics 2017 (PubMed)

  6. Human Polyclonal POSTN Primary Antibody for IHC, IHC (p) - ABIN4892111 : Ratajczak-Wielgomas, Grzegrzolka, Piotrowska, Matkowski, Wojnar, Rys, Ugorski, Dziegiel: Expression of periostin in breast cancer cells. in International journal of oncology 1970 (PubMed)

  7. Human Monoclonal POSTN Primary Antibody for ICC, IF - ABIN4344892 : Ratajczak-Wielgomas, Gosk, Rabczyński, Augoff, Podhorska-Okołów, Gamian, Rutowski: Expression of MMP-2, TIMP-2, TGF-β1, and decorin in Dupuytren's contracture. in Connective tissue research 2012 (PubMed)

More Antibodies against POSTN Interaction Partners

Human Periostin, Osteoblast Specific Factor (POSTN) interaction partners

  1. On 10 mug/ml periostin or TGFBI, more eosinophils adopted a flattened pancake morphology with dispersed granules and nuclear lobes, and slower migration. Conversion between acorn and pancake morphologies were observed. TGFBI or periostin supports two modes of migration by IL-5 family cytokine-activated eosinophils.

  2. Authors found that the antioxidant cinnamaldehyde activated the NRF2/HMOX1 pathway. Cinnamaldehyde also alleviated TGF-beta1- and IL-13-mediated production of reactive oxygen species and subsequent POSTN upregulation in dermal fibroblasts. NRF2 silencing abolished the cinnamaldehyde-mediated downregulation of POSTN.

  3. Periostin levels were significantly higher in patients with ameloblastoma than in controls. Moreover, Periostin levels in patients with ameloblastoma were significantly associated with the number of disease. Furthermore, the results suggested that Periostin expression significantly promoted the proliferation and migration, in addition to cell cycle progression of AM-1 cells.

  4. prominent in the superficial dermis in both pemphigus vulgaris and bullous pemphigoid lesions

  5. Findings indicate that Postn deficiency impairs liver regeneration in mice after partial hepatectomy and Postn might be a novel promoter for liver regeneration.

  6. Increased serum periostin concentrations are associated with the presence of diabetic retinopathy in patients with type 2 diabetes mellitus.

  7. Periostin expression is not significantly linked to metastatic disease in pancreatic ductal adenocarcinoma.

  8. high-level mechanical stretch induces apoptotic cell death, and that periostin plays a protective role against mechanical stretch-induced apoptosis in osteoblastic cells.

  9. Both periostin and SCCA may play a role in the pathogenesis of acute bronchitis due to respiratory syncytial virus

  10. serum levels significantly differed between eosinophilic and non-eosinophilic chronic sinusitis with nasal polyps

  11. Periostin contributes to skin fibrosis by enhancing TGF-beta signaling via Smad 7 inhibition, which may lead to extracellular matrix deposition and periostin generation.

  12. the occurrence of periostin in the healthy adult human tooth without co-localization with proteins involved in tooth mineralization, the expression of which it regulates

  13. Periostin is down-regulated in ankylosing spongylitis patients with highly active disease and may contribute to disease pathogenesis through an interaction with Wnt signaling.

  14. In the Title.

  15. Our study demonstrates differences in Periostin (PN) expression in histological subtypes of Papillary Thyroid Carcinoma. Our results plead in favor of a dominant protumorigenic role of stromal PN, while the action of epithelial PN is less noticeable

  16. POSTN may function as a protective factor for osteoblasts during this process by inhibiting the eIF2alphaATF4 pathway.

  17. Circulating levels of DLL1 and POSN were higher in patients with severe dilated cardiomyopathy and correlated with the degree of diastolic dysfunction.

  18. High concentrations of serum periostin in acute ICH patients are associated with increasing severity and a poor functional prognosis

  19. These results demonstrate that POSTN promotes the osteogenic differentiation of mesenchymal stem cells (MSCs) and that CTLA4 enhances the ectopic osteogenesis of MSCs-CTLA4-based tissue-engineered bone.

  20. measurement of a periostin fragment resulting from in vivo cathepsin K digestion may help to identify subjects at high risk of fracture.

Mouse (Murine) Periostin, Osteoblast Specific Factor (POSTN) interaction partners

  1. Inhibition of periostin could be important for suppressing capsule formation on silicone implants after in vivo implantation.

  2. Unaffected by Postn, Vav-Itgav(-/-) haematopoietic stem cell proliferate faster in vitro, illustrating the importance of Postn-Itgav interaction.

  3. Periostin-expressing myofibroblasts in the heart derive from tissue-resident fibroblasts of the Tcf21 lineage and are necessary for adaptive healing and fibrosis.

  4. mesenchymal source, specific to cardiovascular tissues, roles in cardiovascular development and disease [review]

  5. Results indicate that periostin is a key player in the development of bleomycin-induced fibrosis and consequent enhancement of tumor cell colonization in the lung.

  6. Periostin gene deletion impairs periosteal cells functions and fracture consolidation.

  7. these data indicate that CatK not only plays a major role in bone remodeling but also modulates modeling-based cortical bone formation by degrading periostin and thereby moderating Wnt-beta-catenin signaling.

  8. Ablation of periostin suppresses post-infarction myocardial regeneration by inhibiting the PI3K/GSK3beta/cyclin D1 signalling pathway, indicating that periostin is essential for myocardial regeneration.

  9. this study shows that periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis

  10. Genetic or pharmaco-genetic inhibition of periostin in animal models of renal disease was efficient in arresting the progression of the kidney pathology. (Review)

  11. TGFBI and periostin act similarly in the heart in affecting fibrosis and disease responsiveness.

  12. Results suggest that stromal cell periostin (POSTN) supports both normal hematopoietic progenitor cells (HPCs) and leukemia-initiating cells in vitro.

  13. the expressions of the periostin splice variants were increased in ischemic retinas.

  14. POSTN regulates the scar formation after spinal cord injuries.

  15. periostin in the extracellular matrix architecture prevents pulmonary leakage of blood fluid, thus increasing the survival rate in mice with acute lung injury

  16. These results indicated that tensile stress load increased the expression levels of PN in mouse peridontal ligaments and human periodontal ligament cells.

  17. POSTN promotes the pulmonary accumulation of myeloid-derived suppressor cells (MDSCs) during the early stage of breast tumour metastasis. Postn deletion decreases neutrophil and monocytic cell populations in the bone marrow of mice and suppresses the accumulation of MDSCs to premetastatic sites.

  18. Fibrillin-2 and periostin are target genes in Osterix-mediated osteoblast differentiation.

  19. Periostin mediates intestinal inflammation through the activation of NF-kappaB signaling, which suggests that periostin is a potential therapeutic target for inflammatory bowel disease.

  20. Thus, these results demonstrate a subcellular role of periostin in promotion of fibronectin secretion from the ER.

Cow (Bovine) Periostin, Osteoblast Specific Factor (POSTN) interaction partners

  1. These results suggest that periostin is one of the local contributing factors in bone and periodontal tissue remodeling following mechanical stress during experimental tooth movement [periostin].

POSTN Antigen Profile

Protein Summary

Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.

Gene names and symbols associated with POSTN

  • periostin (POSTN) antibody
  • periostin, osteoblast specific factor b (postnb) antibody
  • periostin, osteoblast specific factor (postn) antibody
  • periostin, osteoblast specific factor (Postn) antibody
  • periostin (Postn) antibody
  • A630052E07Rik antibody
  • AI747096 antibody
  • fa99h07 antibody
  • LOC100008945 antibody
  • OSF-2 antibody
  • Osf2 antibody
  • PDLPOSTN antibody
  • peri antibody
  • periostin antibody
  • Plf antibody
  • PN antibody
  • postn antibody
  • RP11-412K4.1 antibody
  • wu:fa99h07 antibody
  • wu:fc70f09 antibody
  • zgc:153873 antibody

Protein level used designations for POSTN

periostin , periostin, osteoblast specific factor , rp11-412k4.1 , extracellular adhestion molecule , osteoblast-specific factor 2 , osteoblast specific factor 2 (fasciclin I-like) , periodontal ligament-specific periostin , periostin isoform thy2 , periostin isoform thy4 , periostin isoform thy6 , periostin isoform thy8 , periostin-like factor , periostin variant 6 , periostin variant 7 , periostin variant 8 , periostin variant 9

100062608 Equus caballus
337176 Danio rerio
100008945 Oryctolagus cuniculus
100127174 Xenopus (Silurana) tropicalis
395429 Gallus gallus
10631 Homo sapiens
50706 Mus musculus
361945 Rattus norvegicus
477298 Canis lupus familiaris
281960 Bos taurus
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