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PRDX2 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Additionally we are shipping Peroxiredoxin 2 Kits (45) and Peroxiredoxin 2 Proteins (32) and many more products for this protein.
Showing 10 out of 153 products:
Human Monoclonal Peroxiredoxin 2 Primary Antibody for IF, IHC (p) - ABIN563132
Desmetz, Bascoul-Mollevi, Rochaix, Lamy, Kramar, Rouanet, Maudelonde, Mangé, Solassol: Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009
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Human Polyclonal Peroxiredoxin 2 Primary Antibody for ELISA, WB - ABIN251498
Kato, Kato, Abe, Matsumura, Nishino, Aoki, Itoyama, Asayama, Awaya, Hirano, Ohama et al.: Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ... in Acta neuropathologica 2005
Our findings indicate that Prdx2 might have an important role in the regulation of trophoblast proliferation and apoptosis during early pregnancy, and that its expression is mediated by c-Myc (show MYC Antibodies). Thus, these two proteins may be involved in the pathogenesis of RM and may represent potential therapeutic targets
Data indicate that Prx2 is denitrosylated by Srxn1 (show SRX1 Antibodies)-mediated, and the two proteins physically bind via disulfide bond formation, providing a structural basis for the enzymatic reaction that requires ATP hydrolysis.
Overexpression of peroxiredoxin 2 and VEGFR2 (show KDR Antibodies) in pterygium might be involved in the pathogenesis or recurrence of pterygium. The increase of VEGFR2 (show KDR Antibodies) might be related to the increase of peroxiredoxin 2 in response to excessive reactive oxygen species from ultraviolet exposure.
Knockdown of peroxiredoxin 2 (Prdx2) reduced the self-renewal and sphere formation in colon cancer stem cells (CSCs).
PRDX2 and p-AKT (show AKT1 Antibodies) protein expression were analyzed by immunohistochemistry technology.
Association and oligomerization of Prx (show PRDX6 Antibodies) II could take part in recovery and protection of the CK BB enzyme activity from inactivation during heat-induced stress.
Prx (show PRDX6 Antibodies) II plays a key role in the cancer stem cell self-renewal of hepatocellular carcinoma cells through redox regulation.
Peroxiredoxin-2 (PRDX2) and hemoglobin (show HBB Antibodies)-subunits proteins, which are closely involved in the response to oxidative stress.
High PRDX2 expression is associated with colorectal cancer progression.
Knockdown of forkhead Box M1 (FoxM1 (show FOXM1 Antibodies)) reduced Prx (show PRDX6 Antibodies) II levels in H-ras (show HRAS Antibodies)(G12V)-hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cells, indicating FoxM1 (show FOXM1 Antibodies) as a direct transcription factor of Prx (show PRDX6 Antibodies) II in HCC (show FAM126A Antibodies).
one of the antioxidant enzymes, Prdx-2, was abundantly nitrosylated and temporarily reduced in antioxidant activity, causing transient endogenous hydrogen peroxide (H2O2) accumulation and subsequent X-box binding protein-1s/phosphatidylinositol 3-kinase pathway activation.Prdx-2 nitrosylation could be a potent strategy to affect the pluripotent stem cell-derived cardiomyogenesis.
Oxidative stress promotes PRX2 (show PRRX2 Antibodies) and PRX3 (show PRDX3 Antibodies) hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.
The ventral signal observed for Prdx2 from early stages colocalized with motor neuron markers Isl1 (show ISL1 Antibodies)/2 and FoxP1 (show FOXP1 Antibodies) and strong ventral signal colocalizing with Isl1 (show ISL1 Antibodies)/2 was observed in all rostrocaudal segments of the spinal cord.
Prx2 (show PRRX2 Antibodies) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Antibodies) provide an alternative mechanism to thioredoxin (show TXN Antibodies) and thioredoxin reductase for Prx2 (show PRRX2 Antibodies) recycling.
elevation in hyperoxidized Prxs, notably Prx2 (show PRRX2 Antibodies) and Prx3 (show PRDX3 Antibodies), was observed in several organs from SOD1 (show SOD1 Antibodies)-deficient mice. However, a SOD1 (show SOD1 Antibodies) deficiency had no impact on the wheel-running activity of the mice
PrxII functions as a protective antioxidant enzyme against collagen-stimulated platelet activation and platelet-dependent thrombosis
Prx I and Prx II appear to have a tight association with the mechanism underlying the protection of ESC stemness in developing teratomas.
results suggest that inactivation of PrxII is important for the stability of FoxO1 (show FOXO1 Antibodies) protein, which subsequently mediates Foxp3 (show FOXP3 Antibodies)( ) Treg cell development, thereby attenuating colonic inflammation
PRDX2 neutralizes hydrogen peroxide generated in vivo under the transient hypoxic conditions experienced as erythrocytes pass through the microcirculation.
PRX2 (show PRRX2 Antibodies) battles poly(ADP-ribose) polymerase 1 (show PARP1 Antibodies)- and p53 (show TP53 Antibodies)-dependent prodeath pathways after ischemic injury
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
natural killer cell-enhancing factor B
, thiol-specific antioxidant 1
, thioredoxin peroxidase 1
, thioredoxin-dependent peroxide reductase 1
, Prx II-1
, Trx dependent peroxide reductase 1
, protector protein
, thiol specific antioxidant protein
, thiol-specific antioxidant protein
, thioredoxin dependent peroxide reductase 1
, thioredoxin reductase