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The protein encoded by PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. Additionally we are shipping PPAT Antibodies (77) and PPAT Kits (5) and many more products for this protein.
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purine biosynthetic pathway enzymes PPAT and PAICS, as well as pyruvate kinase activity are increased in lung cancer
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.
, glutamine PRPP amidotransferase
, glutamine phosphoribosylpyrophosphatate amidotransferase
, glutamine phosphoribosylpyrophosphate amidotransferase
, phosphoribosyl pyrophosphate amidotransferase
, amidophosphoribosyltransferase-like protein