Plectin ELISA Kits

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton.

Data Quality
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Type
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    Kit
Antigen
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Reactivity
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Application
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Method Type
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Analytical Method
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Detection Method
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Plate
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Sample
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9 Products
Pre-coated, Samples: Plasma, Serum
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.625-40 ng/mL
Order details Cat. No. ABIN5519200
$630.00
96 tests
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
Pre-coated, Samples: Plasma, Serum, Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.31 ng/mL - 20 ng/mL
Order details Cat. No. ABIN5522200
$641.23
96 tests
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Pre-coated, Samples: Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range1.56 ng/mL - 100 ng/mL
Order details Cat. No. ABIN418427
$736.84
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Pre-coated, Samples: Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range1.56 ng/mL - 100 ng/mL
Order details Cat. No. ABIN1571928
$908.41
Plus shipping costs $45.00
Delivery in 15 to 17 Business Days
Pre-coated, Samples: Plasma, Serum
ReactivityMouse (Murine)
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.78 ng/mL - 50 ng/mL
Order details Cat. No. ABIN6210115
$612.03
96 tests
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Pre-coated, Samples: Plasma, Serum, Tissue Homogenate
ReactivityMouse (Murine)
Detection MethodColorimetric, Competition ELISA
Detection Range0.78-50 ng/mL
Order details Cat. No. ABIN5593036
$754.60
96 tests
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Pre-coated, Samples: Plasma, Serum, Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.312-20 ng/mL
Order details Cat. No. ABIN5593035
$867.90
96 tests
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityMouse (Murine)
Detection MethodColorimetric,
Detection Range0.78-50 ng/mL
Order details Cat. No. ABIN1148444
$875.60
96 tests
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityRat (Rattus)
Detection MethodColorimetric,
Order details Cat. No. ABIN1148445
$875.60
96 tests
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
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Plectin (PLEC) Antigen Profile

Protein Summary

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes (reviewed in PMID: 9701547, 11854008, and 17499243). Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans (PMID: 8633055, 8698233). Until 2010, this locus was named plectin 1 (symbol PLEC1 in human\; Plec1 in mouse and rat) and the gene product had been referred to as 'hemidesmosomal protein 1' or 'plectin 1, intermediate filament binding 500kDa'. These names were superseded by plectin. The plectin gene locus in mouse on chromosome 15 has been analyzed in detail (PMID: 10556294, 14559777), revealing a genomic exon-intron organization with well over 40 exons spanning over 62 kb and an unusual 5' transcript complexity of plectin isoforms. Eleven exons (1-1j) have been identified that alternatively splice directly into a common exon 2 which is the first exon to encode plectin's highly conserved actin binding domain (ABD). Three additional exons (-1, 0a, and 0) splice into an alternative first coding exon (1c), and two additional exons (2alpha and 3alpha) are optionally spliced within the exons encoding the acting binding domain (exons 2-8). Analysis of the human locus has identified eight of the eleven alternative 5' exons found in mouse and rat (PMID: 14672974)\; exons 1i, 1j and 1h have not been confirmed in human. Furthermore, isoforms lacking the central rod domain encoded by exon 31 have been detected in mouse (PMID:10556294), rat (PMID: 9177781), and human (PMID: 11441066, 10780662, 20052759). The short alternative amino-terminal sequences encoded by the different first exons direct the targeting of the various isoforms to distinct subcellular locations (PMID: 14559777). As the expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development (PMID: 10556294, 12542521, 17389230) it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms, as if custom-made for specific requirements of the particular cells. Concordantly, individual isoforms were found to carry out distinct and specific functions (PMID: 14559777, 12542521, 18541706). In 1996, a number of groups reported that patients suffering from epidermolysis bullosa simplex with muscular dystrophy (EBS-MD) lacked plectin expression in skin and muscle tissues due to defects in the plectin gene (PMID: 8698233, 8941634, 8636409, 8894687, 8696340). Two other subtypes of plectin-related EBS have been described: EBS-pyloric atresia (PA) and EBS-Ogna. For reviews of plectin-related diseases see PMID: 15810881, 19945614. Mutations in the plectin gene related to human diseases should be named based on the position in NM_000445 (variant 1, isoform 1c), unless the mutation is located within one of the other alternative first exons, in which case the position in the respective Reference Sequence should be used.

Gene names and symbols associated with Plectin (PLEC) ELISA Kits

  • plectin (LOC100481602) antibody
  • plectin L homeolog (plec.L) antibody
  • plectin (PLEC) antibody
  • plectin (Plec) antibody
  • plectin (LOC786966) antibody
  • AA591047 antibody
  • AU042537 antibody
  • EBS1 antibody
  • EBSO antibody
  • HD1 antibody
  • IFAP300 antibody
  • LGMD2Q antibody
  • Pcn antibody
  • Plec1 antibody
  • PLEC1b antibody
  • Plectin-1 antibody
  • Pltn antibody

Protein level used designations for Plectin (PLEC) ELISA Kits

plectin , plectin-1-like , hemidesmosomal protein 1 , plectin 1, intermediate filament binding protein 500kDa , plectin-1 , plectin 1 , plectin-6 , 300 kDa intermediate filament-associated protein

GENE ID SPECIES
100481602 Ailuropoda melanoleuca
398587 Xenopus laevis
5339 Homo sapiens
18810 Mus musculus
64204 Rattus norvegicus
100682530 Cricetulus griseus
786966 Bos taurus
482083 Canis lupus familiaris
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