Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) ELISA Kits

Human Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) interaction partners

1. ZAC expression was studied in transgenic mice.

2. report here a novel PLAGL1 promoter (P5) derived from the insertion of a primate-specific, MIR3 SINE retrotransposon. P5 is highly utilized in lymphocytes, particularly in T cells, and like P2, directs biallelic transcription

3. Plagl1 is a transcription factor that coordinated the regulation of a subset of imprinted gene network genes and controlled extracellular matrix composition.

4. PLAGL1 methylation/expression may be altered after assisted reproductive technologies.

5. These results suggest that OCT (show Plxna2 ELISA Kits) attenuates SGC-7901 cell proliferation by enhancing P300-HAT (show EP300 ELISA Kits) activity through the interaction of ZAC and P300 (show EP300 ELISA Kits), causing a reduction in pS10-H3 and an increase in acK14-H3. These findings provide insight for future research on OCT (show Plxna2 ELISA Kits) and further demonstrate the potential of OCT (show Plxna2 ELISA Kits) to be used as a therapeutic agent for gastric cancer

6. High PLAGL1 mRNA and protein levels were associated with Clear Cell Renal Cell Carcinoma (show MOK ELISA Kits).

7. Results suggest that dysregulation of PLAGL1 expression may be involved in the progression of colorectal cancer (CRC (show CALR ELISA Kits)) but the patient survival data do not confirm applicability of the PLAGL1 expression level as a prognostic factor in CRC (show CALR ELISA Kits).

8. Fetal growth can be influenced by altered expression of the PLAGL1 gene network in human placenta.

9. DNA deletion and promoter hyper-methylation both contribute to the down-regulation of PLAGL1 in gastric adenocarcinoma

10. There is positive correlations between the ZAC1 DMR methylation index (MI) and estimated fetal weight (EFW) at 32 weeks of gestation, weight at birth and weight at one year of age (respectively, r = 0.15, 0.09, 0.14; P values = 0.01, 0.15, 0.03).

Pig (Porcine) Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) interaction partners

1. PLAGL1 is maternally imprinted in swine. Expression profiling using short-oligonucleotide microarrays of parthenotes and control fetal tissues supports imprinted isoform-specific expression.

2. The expression patterns of PLAGL1 and PEG10 (show PEG10 ELISA Kits) genes in two breeds of swine are reported.

Mouse (Murine) Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) interaction partners

1. Zac1/GPR39 system promotes the formation of type II muscle fibers by phosphorylation of CaMK-II. Cells lacking Zac1/GPR39 system tend to remain stemness and form type I muscle fibers after induced differentiation.

2. Plagl1 is a transcription factor that coordinated the regulation of a subset of imprinted gene network genes and controlled extracellular matrix composition.

3. expression levels of Zac1 need to be kept under strict control to avoid premature cell cycle exit, disrupted neurogenesis and aberrant expression of non-neuronal genes including pluripotency associated factors.

4. Transcription factor MEF2 (show MEF2C ELISA Kits) and Zac1 mediate MIF (show MIF ELISA Kits)-induced GLUT4 (show SLC2A4 ELISA Kits) expression through CD74 (show CD74 ELISA Kits)-dependent AMPK (show PRKAA1 ELISA Kits) activation in cardiomyocytes

5. we show that the maternally imprinted gene Zac1 is a critical regulator of neocortical development

6. Zac1 interacts with two cis-regulatory elements in the Tcf4 (show TCF4 ELISA Kits) gene locus.

7. results indicate ZAC is a negative regulator of the acute stimulatory effects of glucose on beta-cells. It provides an explanation for both insulin (show INS ELISA Kits) deficiency in the neonate and the later relapse of diabetes in patients with transient neonatal diabetes mellitus cases

8. Hymai and Plagl1it RNAs both have potentially high affinity for Trithorax chromatin regulators.

9. identified the guanine nucleotide exchange factor Rasgrf1 (show RASGRF1 ELISA Kits) as a direct Zac1/Plagl1 target gene in beta cells

10. Zac1 inhibits nuclear factor Kappa B activity by interacting with the C-terminus of the p65 (show NFkBP65 ELISA Kits) subunit, which suppresses the phosphorylation of p65 (show NFkBP65 ELISA Kits) at Ser468 and Ser536 residues