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Steroid membrane receptor. Additionally we are shipping PAQR7 Kits (12) and PAQR7 Proteins (4) and many more products for this protein.
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Utilizing both genetic and pharmacologic approaches, the authors establish that sex steroid effects on human melanin synthesis are mediated by the membrane-bound, steroid hormone receptors G protein-coupled estrogen receptor (GPER), and progestin and adipoQ receptor 7 (PAQR7).
The effects of progesterone treatment on the expression levels of progesterone receptor membrane component 1 (PGRMC1), plasminogen activator inhibitor 1 RNA-binding protein (PAIRBP1), and progestin and adipoQ receptor 7 (PAQR7) on both mRNA and protein levels were investigated in spheroids derived from human glioma cell lines U-87 MG and LN-229.
Data show abundant mPRalpha (PAQR7), mPRbeta (PAQR8), and mPRgamma (PAQR5), but not classical nuclear PR (A or B isoforms) mRNA expression and mPRalpha protein expression in a panel of commonly used ovarian cancer cell lines.
cDNAs for the mPR alpha subtypes from spotted seatrout (st-mPRalpha) and humans (hu-mPRalpha) encode progestin receptors that display many functional characteristics of G protein-coupled receptors.
Heterologous expression of MPRA in yeast confirms its ability to function as a membrane progesterone receptor.
mPRalpha is an intermediary in progestin stimulation of sperm motility in humans by a mechanism involving G-protein activation
Paqr7 and Paqr8 are expressed in the midbrain ventral tegmental area of proestrous mice.
Steroid membrane receptor. May be involved in oocyte maturation (By similarity).
, mPR alpha
, membrane progestin receptor alpha
, progestin and adipoQ receptor family member 7
, PPAR-gamma-induced liver protein
, putative membrane steroid receptor
, progestin and adipoQ receptor family member VII, membrane progestin receptor alpha variant 2
, progestin and adipoQ receptor family member VII, membrane progestin receptor alpha variant 3