Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Binds to F-actin. Additionally we are shipping Proline-serine-threonine Phosphatase Interacting Protein 2 Proteins (3) and many more products for this protein.
Showing 10 out of 20 products:
PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN.
a new PSTPIP1/PTPN6/SHIP1/2-dependent negative feedback mechanism that counterbalances Src and PI(3,4,5)P3 signalling to control osteoclast cell polarity and activity during bone resorption
SHIP1 and Csk are part of the PSTPIP2-dependent inhibitory network that prevents the development of autoinflammatory disease.
PSTPIP2 could play a role in innate immunity and development of autoinflammatory bone disorders, and may be associated with the pathogenesis of SAPHO syndrome.
inflammasome-independent production of IL-1beta has a critical role in osteolytic bone disease; PSTPIP2 is a negative regulator of caspase-1-autonomous IL-1beta production
IL-1beta has a role in mediating autoinflammatory disease in Pstpip2-deficient mice
Knockdown of PSTPIP2 inmacrophages enhances the assembly of FBP17, leading to'hyperactivation' of actin nucleation at podosomes and ECM degradation.
PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts.
our pstpip2 mutant mice provide a new model for investigating the potential mechanisms of inflammatory pain.
MAYP directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages.
A missense mutation in pstpip2 is associated with the autoinflammatory disorder chronic multifocal osteomyelitis.
mutations are associated with spontaneous disease in mouse model of osteomyelitis
PSTPIP2 deficiency leads to autoinflammatory disease.
Binds to F-actin. May be involved in regulation of the actin cytoskeleton.
proline-serine-threonine phosphatase interacting protein 2
, proline-serine-threonine phosphatase-interacting protein 2
, similar to proline-serine-threonine phosphatase interacting protein 1
, proline-serine-threonine phosphatase-interacting protein 2-like
, PEST phosphatase-interacting protein 2
, macrophage actin-associated tyrosine-phosphorylated protein