anti-Prolyl Endopeptidase (PREP) Antibodies

The protein encoded by PREP is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Additionally we are shipping Prolyl Endopeptidase Kits (9) and Prolyl Endopeptidase Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PREP 5550 P48147
PREP 19072 Q9QUR6
PREP 83471 O70196
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Top anti-Prolyl Endopeptidase Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PREP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HT1080 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PREP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Muscle 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC   100 μg 6 to 7 Days
$429.84
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Available
$363.46
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Details
Cow Goat Un-conjugated EIA, IHC (p) AP31109PU-N PREP antibody staining of Paraffin Embedded Human Kidney at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated WB PREP Antibody (Center)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PREP antibody detected the PREP protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details

Top referenced anti-Prolyl Endopeptidase Antibodies

  1. Dog (Canine) Polyclonal PREP Primary Antibody for ELISA - ABIN547681 : Momeni, Nordström, Horstmann, Avarseji, Sivberg: Alterations of prolyl endopeptidase activity in the plasma of children with autistic spectrum disorders. in BMC psychiatry 2005 (PubMed)

More Antibodies against Prolyl Endopeptidase Interaction Partners

Human Prolyl Endopeptidase (PREP) interaction partners

  1. These findings provide evidence for newly-discovered roles for PREP in mechanisms regulating cellular plasticity through NCAM and PSA-NCAM.

  2. Study shows that the expression of POP increases with hepatocyte steatosis suggesting an important role in hepatocytes steatosis and possibly NAFLD.

  3. It was found that human PREP behaves identically to the porcine homolog, displaying a double bell-shaped pH profile and a pH-dependent solvent kinetic isotope effect of the kcat/Km, features that set it apart from the related exopeptidase dipeptidyl peptidase IV (DPP IV).

  4. TLR4 activation releases prolyl endopeptidase containing exosomes from airway epithelial cells.

  5. This study found that circulating PREP activity was substantially reduced in all cirrhotic patients but those changes did not have evident correlation to hepatic encephalopathy.

  6. PEP was significantly and positively associated with delinquent, aggressive, externalizing and internalizing behavior subscales.

  7. PREP redox inactivation is due to oxidation of cysteine residues and consequent oligomerization through intermolecular disulfide bonds.

  8. Data indicate that SAXS analysis showed that presequence protease (hPreP) open states and substrate binding dynamics.

  9. The determination of PEP activity in the plasma may be a safe, minimally invasive and inexpensive way to define the aggressiveness of CRC in daily practice.

  10. first demonstration of colocalization of PREP and pathological proteins in the human brain, supporting the view that, at least in spatial terms, PREP could be associated with pathogenesis of neurodegenerative diseases

  11. These results indicate that POP may be a positive regulator of cell cycle progression by regulating the exit from and/or reentry into the cell cycle by KATO III cells.

  12. interaction between prolyl oligopeptidase and glyceraldehyde-3-phosphate dehydrogenase is required for cytosine arabinoside-induced glyceraldehyde-3-phosphate dehydrogenase nuclear translocation and cell death

  13. Oxidative stress and the levels of endogenous plasma prolyl oligopeptidase (PREP) inhibitor alpha-2-macroglobulin (alpha2M) decrease PREP activity in multiple sclerosis patients.

  14. PREP may be associated with secretory processes as well as in reproduction. A more abundant expression of PREP in malignant than benign tumors suggests that PREP may be associated with expansion and metastasis of tumors.

  15. analysis of the substrate preferences of two post-proline cleaving endopeptidases, prolyl oligopeptidase and fibroblast activation protein alpha

  16. PREP is a regulatory target and a regulatory element in cell signalling. This is the first report of a direct influence of a cell signalling molecule, retinoic acid, on PREP expression.

  17. Molecular modeling and docking based approaches were used to unravel questions like differences in ligand binding affinities in three POP species (porcine, human and A. thaliana).

  18. These results indicate that POP is a part of the machinery that controls the cell cycle.

  19. Results indicate that there is no strong and direct interaction between POP and GAP43 at physiological conditions.

  20. The constitutive expression of PREP mRNA in chronic lymphocytic leukemia was demonstrated.

Pig (Porcine) Prolyl Endopeptidase (PREP) interaction partners

  1. Ion mobility mass spectrometry (IMMS) experiments detected two species of PREP that correlated well with the open and closed conformations in dynamic equilibrium. Therefore, these findings emphasize the value of IMMS for the study of multiple co-existing conformations of large proteins in slow equilibrium in solution.

  2. Molecular modeling and docking based approaches were used to unravel questions like differences in ligand binding affinities in three POP species (porcine, human and A. thaliana).

Mouse (Murine) Prolyl Endopeptidase (PREP) interaction partners

  1. Prolyl oligopeptidase expression and role in the placental spongiotrophoblast differentiation.

  2. PREP regulates the function of dopamine transporter, possibly by controlling the phosphorylation and transport of dopamine transporter into the striatum or synaptic membrane.

  3. Taken together, these data suggest that PREP can enhance alpha-synuclein toxicity in vivo.

  4. involved in trophoblast stem cell differentiation in placenta

  5. These findings might be explained as possible alteration in brain plasticity caused by PREP deficiency, which in turn affect behaviour and brain development

  6. Lung ischemia-reperfusion injury causes a dysregulation of circulating Ang 2 levels and plasma PREP activity, although no direct link between both phenomena could be shown.

  7. TLR4 activation releases prolyl endopeptidase containing exosomes from airway epithelial cells.

  8. the expression of prolyl endopeptidase could be necessary for a correct reproductive function

  9. As PREP inhibition also enhances autophagic clearance of aSyn, PREP inhibitors may reduce accumulation of aSyn inclusions via a dual mechanism and are thus a novel therapeutic candidate for synucleinopathies.

  10. lncPrep+96kb could play a role in the POP gene activation in the granulosa cell.

  11. PREP knockdown mice (Prep(gt/gt)) exhibited glucose intolerance, decreased fasting insulin, increased fasting glucagon levels, and reduced glucose-induced insulin secretion compared with wild-type controls.

  12. The study reveals a role for prolyl endopeptidase in mediating hippocampal plasticity and spatial memory formation.

  13. The POP promoter was sufficient for the appropriate localization in the placenta if it was not subject to position effect.

  14. the cytoplasmic and membrane-associated POP have distinct roles in different types of placental cells.

  15. alpha-MSH(1-13) is an in vivo substrate of PREP.

  16. Cigarette smoke-induced lung emphysema is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.

  17. in vitro reporter analysis indicated that CGI-2 enhanced POP promoter activity and its effect was significantly reduced by DNA methylation

  18. Murine T cells expressing high activity of prolyl endopeptidase are susceptible to activation-induced cell death.

  19. Report distribution of prolyl oligopeptidase in the mouse whole-body sections and peripheral tissues.

  20. peptidase activity is not required for PO function in neurons and suggest that PO instead acts by binding to cytosolic proteins that control growth cone and synaptic function.

Prolyl Endopeptidase (PREP) Antigen Profile

Protein Summary

The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides.

Gene names and symbols associated with PREP

  • prolyl endopeptidase (RB12337) antibody
  • prolyl endopeptidase (AM1_4884) antibody
  • Prolyl endopeptidase (ppce) antibody
  • prolyl endopeptidase (PREP) antibody
  • prolyl endopeptidase (Prep) antibody
  • prolyl endopeptidase (prep) antibody
  • AI047692 antibody
  • AI450383 antibody
  • D10Wsu136e antibody
  • im:7140031 antibody
  • PE antibody
  • PEP antibody
  • Pop antibody
  • rPop antibody
  • zgc:110670 antibody

Protein level used designations for PREP

prolyl endopeptidase , Prolyl endopeptidase , dJ355L5.1 (prolyl endopeptidase) , post-proline cleaving enzyme , prolyl oligopeptidase , PE

GENE ID SPECIES
1791314 Rhodopirellula baltica SH 1
5683684 Acaryochloris marina MBIC11017
100305172 Oncorhynchus mykiss
5550 Homo sapiens
481945 Canis lupus familiaris
445540 Sus scrofa
286818 Bos taurus
19072 Mus musculus
83471 Rattus norvegicus
553791 Danio rerio
421785 Gallus gallus
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