Protamine 1 (PRM1) ELISA Kits

Human Protamine 1 (PRM1) interaction partners

1. Protamine-1 and protamine-2 (show PRM2 ELISA Kits) mRNA levels as well as the protamine mRNA ratio and all routine semen parameters revealed significant differences between recurrent miscarriage couples and healthy volunteers. Values of protamine-1 and protamine-2 (show PRM2 ELISA Kits) mRNAs were significantly higher and the protamine mRNA ratio was significantly lower in couples with recurrent miscarriage.

2. examinded the association between protamine gene alleles (PRM1 c.-190C>A, PRM1 c.197G>T, and PRM2 (show PRM2 ELISA Kits) c.248C>T), and YBX2 (c.187T>C and c.1095 + 16A>G) and male infertility. We found that the AA and CA genotypes of the PRM1 c.-190C>A polymorphism had a significant association with infertility (p < 0.001) and the AA genotype was also highly significantly associated with high sperm DNA damage (p < 0.001).

3. The KDM3A to PRM1 mRNA expression ratio can be used as a reliable marker of successful testicular sperm extraction in men with obstructive and non-obstructive azoospermia with 95% sensitivity.

4. Single nucleotide polymorphisms in the human PRM1 gene are associated with a genetic risk factor for idiopathic oligozoospermia.

5. Studies indicate that ribonucleotide reductase M1 polypeptide (RRM1 (show RRM1 ELISA Kits)) expression is associated with the response rate and overall survival rate of advanced NSCLC patients treated with gemcitabine-based chemotherapy.

6. The expressed human protamine1 in two fast-growing cell systems, E. coli and HeLa cells. The protamine 1 expression significantly attenuated cell proliferation when compared with control cells.

7. the quantity of PRM1, PRM2 (show PRM2 ELISA Kits), and TNP2 (show TNP2 ELISA Kits) transcripts and the PRM1/PRM2 (show PRM2 ELISA Kits) mRNA ratio affect spermiogenesis, sperm morphology

8. Single nuclotide polymorphisms in PRM1 gene is associated with male infertility.

9. genetic association study in Han population in China: Data suggest that an SNP in PRM1 (rs35576928; T allele; 34R>S) is associated with severe oligozoospermia and can play a protective role against this disease.

10. The SNP of PRM1-190C- > A might be associated with teratozoospermia-induced male infertility in the Han Chinese.

Mouse (Murine) Protamine 1 (PRM1) interaction partners

1. Data show that male mice from lines showing moderate transgene expression were fully fertile whereas strong overexpression of the Prm1-EGFP fusion protein resulted in complete and dominant male sterility.

2. docking of protamine 1 to the nuclear envelope is an important intermediate step in spermiogenesis

3. Germ cell nuclear factor acts as a repressor of basal transcription on both the Protamine 1 and Protamine 2 (show PRM2 ELISA Kits) promoters.

4. JHDM2A directly binds to and controls the expression of transition nuclear protein 1 (Tnp1 (show TNP1 ELISA Kits)) and protamine 1 (Prm1) genes, the products of which are required for packaging and condensation of sperm chromatin

5. Study shows that protamine 1 and 2 mRNAs, which are specific to the round spermatid stage, are repressed at the two-pronuclei and two-cell stages postfertilization, respectively, in embryos created by round spermatid injection, by distinct mechanisms.

Cow (Bovine) Protamine 1 (PRM1) interaction partners

1. This study was conducted to isolate high-quality RNA from mature spermatozoa and to monitor the expression profile of PRM1 and PRM2 (show PRM2 ELISA Kits) gene in ejaculated spermatozoa of normal and motility impaired bulls.

Pig (Porcine) Protamine 1 (PRM1) interaction partners

1. Porcine spermatozoa may delivery CLU (show CLU ELISA Kits), PRM1 and PRM2 (show PRM2 ELISA Kits) mRNAs to the oocyte, which may contribute to zygotic and early embryonic development.