anti-Protein Kinase, CGMP-Dependent, Type I Antibodies

Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II).

Data Quality
  • 31
Type
  • 88
    Primary antibodies
Antigen
  • 88
Reactivity
  • 84
  • 44
  • 22
  • 6
  • 3
Application
  • 82
  • 43
  • 38
  • 18
  • 10
Detection Method
  • 3
Host
  • 69
  • 19
Clonality
  • 71
  • 17
Clone
  • 7
  • 3
  • 2
  • 1
  • 1
Binding Specificity
  • 12
  • 11
  • 7
  • 6
  • 5
Conjugate
  • 67
  • 4
  • 3
  • 2
  • 2
Isotype
  • 43
  • 8
  • 6
  • 3
  • 2
Format
  • 62
  • 1
Suggested next Filters
88 Products
ReactivityHuman, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN615270
$511.50
50 μg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IF, IHC, IHC (p), WB
Order details Cat. No. ABIN1500243
$522.50
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN3016256
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC (p), WB
Order details Cat. No. ABIN2854933
$509.08
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman
Application IF, WB
Order details Cat. No. ABIN519211
$440.00
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN562400
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC (p), ELISA, WB
Order details Cat. No. ABIN562402
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC, ELISA, WB
Order details Cat. No. ABIN3029798
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IF, IHC, WB
Order details Cat. No. ABIN2718494
$482.90
0.1 mL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application FACS, IF, WB
Order details Cat. No. ABIN2718495
$482.90
0.1 mL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine)
Application WB
Order details Cat. No. ABIN2854616
$509.08
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN1874320
$368.95
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, IHC, WB
Order details Cat. No. ABIN6264429
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN519212
$425.71
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN544150
$431.43
400 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
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Protein Kinase, CGMP-Dependent, Type I (PRKG1) Antigen Profile

Protein Summary

Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.

Gene names and symbols associated with PRKG1

  • protein kinase, cGMP-dependent, type Ia (prkg1a) antibody
  • protein kinase, cGMP-dependent, type I (PRKG1) antibody
  • protein kinase, cGMP-dependent, type I (prkg1) antibody
  • protein kinase, cGMP-dependent, type 1 (Prkg1) antibody
  • protein kinase, cGMP-dependent, type I (Prkg1) antibody
  • 1 antibody
  • AW125416 antibody
  • cGK antibody
  • cGK1 antibody
  • cGK 1 antibody
  • CGKI antibody
  • cGKI-alpha antibody
  • cGKI-beta antibody
  • Gm19690 antibody
  • PKG antibody
  • Pkgi antibody
  • prkg1 antibody
  • Prkg1b antibody
  • Prkg1beta antibody
  • Prkgr1b antibody
  • zgc:63955 antibody

Protein level used designations for PRKG1

cGMP-dependent protein kinase 1 , protein kinase, cGMP-dependent, type I , cGMP-dependent protein kinase 1, beta isozyme , cGMP-dependent protein kinase I alpha , cGK I alpha , cGMP-dependent protein kinase 1-like , cGMP dependent protein kinase type 1 , protein kinase, cGMP-dependent, regulatory, type I, beta , CGK 1 alpha , cGK 1 beta , cGK1 , cGKI-alpha , cGMP-dependent protein kinase 1, alpha isozyme , cGMP-dependent protein kinase I , cGK 1 , PKG1 alpha , cGMP-dependent protein kinase type 1 alpha , cGMP-dependent protein kinase type I beta

GENE ID SPECIES
394005 Danio rerio
744467 Pan troglodytes
100049290 Oryzias latipes
100388016 Callithrix jacchus
54286 Rattus norvegicus
5592 Homo sapiens
282004 Bos taurus
19091 Mus musculus
100008694 Oryctolagus cuniculus
733640 Sus scrofa
423682 Gallus gallus
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