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anti-Protein Kinase C, delta Binding Protein (PRKCDBP) Antibodies

The protein encoded by PRKCDBP was identified as a binding protein of the protein kinase C, delta (PRKCD). Additionally we are shipping Protein Kinase C, delta Binding Protein Kits (7) and Protein Kinase C, delta Binding Protein Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRKCDBP 112464 Q969G5
PRKCDBP 109042 Q91VJ2
PRKCDBP 85332 Q9Z1H9
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Top anti-Protein Kinase C, delta Binding Protein Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Prkcdbp Antibody Titration: 1.0 ug/ml Positive Control: Mouse Stomach 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC, WB Antibody (0.1µg/ml) staining of Human Adipose cell llysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Antibody (0.3µg/ml) staining of Mouse Ovary (A) and Rat Uterus (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg 2 to 3 Days
$360.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
$484.00
Details
Dog Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Uterus, Myometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-PRKCDBP / CAVIN3 antibody IHC staining of human uterus, myometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of MCF-7 cells, using PRKCDBP antibody. ABIN6272879 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details
Cow Goat Un-conjugated EIA, WB   0.1 mg 4 to 8 Days
$462.00
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p), WB Anti-PRKCDBP / CAVIN3 antibody IHC staining of human lung, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

Top referenced anti-Protein Kinase C, delta Binding Protein Antibodies

  1. Human Polyclonal PRKCDBP Primary Antibody for ELISA, IHC - ABIN4347315 : McMahon, Zajicek, Li, Peyton, Minna, Hernandez, Luby-Phelps, Anderson: SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function. in The EMBO journal 2009 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PRKCDBP Primary Antibody for ELISA, WB - ABIN4347316 : Bastiani, Liu, Hill, Jedrychowski, Nixon, Lo, Abankwa, Luetterforst, Fernandez-Rojo, Breen, Gygi, Vinten, Walser, North, Hancock, Pilch, Parton: MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. in The Journal of cell biology 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal PRKCDBP Primary Antibody for ELISA, WB - ABIN566689 : Bai, Deng, Li, Wang, An, Deli, Gao, Xie, Dai, Cong: Down-regulation of the cavin family proteins in breast cancer. in Journal of cellular biochemistry 2011 (PubMed)

More Antibodies against Protein Kinase C, delta Binding Protein Interaction Partners

Human Protein Kinase C, delta Binding Protein (PRKCDBP) interaction partners

  1. PRKCDBP variants may be risk factors of major depressive disorder.

  2. Rather than forming a single coat complex containing the three cavin family members, single-molecule analysis reveals an exquisite specificity of interactions between cavin1, cavin2 and cavin3.

  3. cavin3 is recruited to the caveolae coat by cavin1 to interact with caveolin1 and regulate the duration time of caveolae at the plasma membrane.

  4. in vivo consequences of cavin-3 knockout are increased lactate production and cachexia

  5. These results demonstrate that mucosal expression of PRKCDBP correlated strongly with TNF-alpha expression in UC patients and that infliximab therapy resulted in profound reductions in both PRKCDBP and TNF-alpha.

  6. we found loss at 11p15 to be a marker for triple-negative breast cancer and breast cancer brain metastases and PRKCDBP to be a potential target gene in this locus.

  7. individuals with the variant homozygous CC genotype of PRKCDBP rs1051992 were at higher risk for developing endometrial cancer, but this genotype was a favorable prognostic factor once cancer was present

  8. The cavin family protein Polymerase 1 and transcript release factor, SRBC and serum deprivation response protein were down regulated in breast cancer cell lines and breast tumor tissue.

  9. Data indicate that PRKCDBP expression was hardly detectable in 29 of 80 (36%) primary tumors and 11 of 19 (58%) cell lines.

  10. Our data demonstrate that epigenetic inactivation of hSRBC due to aberrant promoter hypermethylation is a common event and might be implicated in human ovarian tumorigenesis.

  11. Data show low or moderate methylation was found in seven selected genes BAD, BBC3, CAV1, CDK2AP1, NPM1, PRKCDBP and THEM4.

  12. hSRBC is a candidate tumor suppressor gene involved in lung cancer pathogenesis, where expression is frequently inactivated by methylation and other mechanisms

  13. hSRBC is a novel tumor suppressor whose epigenetic inactivation contributes to the malignant progression of gastric tumors, in part, through attenuated p53 response to stresses.

  14. Results suggest that SRBC (sdr-related gene product that binds to c-kinase) and two other family members [PTRF (Pol I and transcription release factor) and SDPR] function as caveolin adapter molecules that regulate caveolae function.

  15. Human SRBC is located within the 11p15.5-p15.4 tumor suppressor region and is inactivated in breast and lung cancers.

Mouse (Murine) Protein Kinase C, delta Binding Protein (PRKCDBP) interaction partners

  1. studies establish a role of cavin-3 in the formation of caveolae in vivo but also show that the physiological consequences of cavin-3 ablation are modest

  2. The roles of cavins 2 and 3 in caveolar morphogenesis in vivo, are reported.

Protein Kinase C, delta Binding Protein (PRKCDBP) Antigen Profile

Protein Summary

The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.

Gene names and symbols associated with PRKCDBP

  • caveolae associated protein 3 (CAVIN3) antibody
  • caveolae associated 3 (Cavin3) antibody
  • caveolae associated protein 3 (Cavin3) antibody
  • 3110015B12Rik antibody
  • 6330514M23Rik antibody
  • cavin-3 antibody
  • CAVIN3 antibody
  • DIG-2 antibody
  • HSRBC antibody
  • PRKCDBP antibody
  • Srbc antibody

Protein level used designations for PRKCDBP

protein kinase C, delta binding protein , protein kinase C delta-binding protein , sdr-related gene product that binds to c-kinase , serum deprivation response factor-related gene product that binds to C-kinase , cavin-3 , D3T-inducible gene 2 protein , PKC-delta binding protein , dithiolethione-inducible gene 2 protein , dithiolethione-inducible gene-2 , sdr-elated gene product that binds to c-kinase

GENE ID SPECIES
450988 Pan troglodytes
112464 Homo sapiens
476831 Canis lupus familiaris
510203 Bos taurus
109042 Mus musculus
85332 Rattus norvegicus
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