Protein Kinase N1 (PKN1) ELISA Kits

The protein encoded by PKN1 belongs to the protein kinase C superfamily. Additionally we are shipping PKN1 Antibodies (38) and PKN1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PKN1 5585 Q16512
PKN1 320795 P70268
PKN1 29355 Q63433
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Top PKN1 ELISA Kits at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.117 ng/mL 0.31 ng/mL - 20 ng/mL   96 Tests Log in to see 13 to 16 Days
$530.53
Details
Mouse 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$630.00
Details
Rat 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$638.00
Details
Pig 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 0.375 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Guinea Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for PKN1 Interaction Partners

Human Protein Kinase N1 (PKN1) interaction partners

  1. Steady-state kinetic analysis revealed that PKN1-3 follows a sequential ordered Bi-Bi (show CACNA1A ELISA Kits) kinetic mechanism, where peptide substrate binding is preceded by ATP binding. This kinetic mechanism was confirmed by additional kinetic studies for product inhibition and affinity of small molecule inhibitors.

  2. Pkn1 is not required for tumorigenesis initiated by loss of Pten. Triple knockout of Pten, Pkn1, and Pkn2 in mouse prostate results in squamous cell carcinoma, an uncommon but therapy-resistant form of prostate cancer.

  3. PKN1 activity was up-regulated by the active RhoA (show RHOA ELISA Kits) mutant (G14V) and suppressed by RhoA (show RHOA ELISA Kits) T19N. PKN1 siRNA interrupted the ability of RhoA (show RHOA ELISA Kits) to promote ESC proliferation and DNA synthesis. The effect of RhoA (show RHOA ELISA Kits) on ESC proliferation is mediated by activation of the PKN1-cyclin D1 (show CCND1 ELISA Kits) pathway in vitro.

  4. TXA2-mediated neoplastic responses in prostate adenocarcinoma PC-3 cells occur through a PRK1/PRK2-dependent mechanism.

  5. Transcriptome and interactome analyses uncover that PRK1 regulates expression of migration-relevant genes by interacting with the scaffold protein (show HOMER1 ELISA Kits) sperm-associated antigen 9 (SPAG9/JIP4 (show SPAG9 ELISA Kits)).

  6. Data indicate that Salmonella SspH1 catalyzes the ubiquitination and proteasome-dependent degradation of PKN1 in cells.

  7. Protein kinase N1 inhibits Wnt/b-catenin signaling and apoptosis in melanoma cells.

  8. Protein kinase N1 is a novel substrate of NFATc1 (show NFATC1 ELISA Kits)-mediated cyclin D1 (show CCND1 ELISA Kits)-CDK6 (show CDK6 ELISA Kits) activity and modulates vascular smooth muscle cell division and migration leading to inward blood vessel wall remodeling.

  9. PKN isoforms are not simply redundant in supporting migration, but appear to be linked through isoform specific regulatory domain properties to selective upstream signals. It

  10. Data show that just one contact site as being relevant for binding of RhoA (show RHOA ELISA Kits) and domain from PRK1, and the HR1b domain was found not to contribute to RhoA (show RHOA ELISA Kits) binding.

Mouse (Murine) Protein Kinase N1 (PKN1) interaction partners

  1. In mice, phosphorylation-regulated (show PHAX ELISA Kits) neutrophil polarization mechanism is driven by PKN1-mediated phosphorylation of a newly identified RAB21 effector RPH3A (show RPH3A ELISA Kits).

  2. Pkn1 is not required for tumorigenesis initiated by loss of Pten. Triple knockout of Pten, Pkn1, and Pkn2 in mouse prostate results in squamous cell carcinoma, an uncommon but therapy-resistant form of prostate cancer.

  3. Mechanistically, Yersinia pseudotuberculosis YopM recruits and activates the mouse host kinases PRK1 and PRK2 to negatively regulate pyrin (show MEFV ELISA Kits) by phosphorylation.

  4. Protein kinase N1, a cell inhibitor of Akt (show AKT1 ELISA Kits) kinase, has a central role in quality control of germinal center formation

  5. PKN is activated by ischemia/reperfusion and inhibits apoptosis of cardiac myocytes, thereby protecting the heart from I/R injury.

  6. Leishmania mexicana infectivity is associated with differential expression of protein kinase C (show PKC ELISA Kits)-like triggered during a cell-cell contact

  7. Pkn1 is involved in ganglioside signals that regulate TNF-alpha (show TNF ELISA Kits) signaling and synthesis.

Fruit Fly (Drosophila melanogaster) Protein Kinase N1 (PKN1) interaction partners

  1. polarity-induced spatiotemporal control of Rok (show ROCK1 ELISA Kits) and Pkn is important for unequal cortical expansion, ensuring correct cleavage furrow positioning and the establishment of physical asymmetry.

  2. The delorean phenotype, with its associated defects in wing morphology, provides evidence of a role for PKN in adult morphogenetic processes.

  3. Drosophila protein kinase N is a negative regulator of actin-myosin activity during oogenesis.

  4. identified a requirement for Pkn in wing morphogenesis, thereby revealing the first postembryonic function for Pkn

PKN1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with Protein Kinase N1 (PKN1) ELISA Kits

  • protein kinase N1 (PKN1) antibody
  • protein kinase N1 (Pkn1) antibody
  • protein kinase N1b (pkn1b) antibody
  • protein kinase N1 (pkn1) antibody
  • Protein kinase N (Pkn) antibody
  • 3-2 antibody
  • CG2049 antibody
  • CG2055 antibody
  • CT6637 antibody
  • CT6660 antibody
  • DBK antibody
  • Dmel\\CG2049 antibody
  • dPKN antibody
  • F730027O18Rik antibody
  • l(2)06736 antibody
  • l(2)45Ca antibody
  • PAK-1 antibody
  • PAK1 antibody
  • Pk45C antibody
  • Pk?3 antibody
  • Pkn antibody
  • PKN-ALPHA antibody
  • PKN1 antibody
  • PRK1 antibody
  • PRK2 antibody
  • Prkcl1 antibody
  • Stk3 antibody
  • v(2)rG232 antibody

Protein level used designations for Protein Kinase N1 (PKN1) ELISA Kits

protease-activated kinase 1 , protein kinase C-like 1 , protein kinase C-like PKN , protein kinase C-related kinase 1 , protein kinase PKN-alpha , protein-kinase C-related kinase 1 , serine-threonine kinase N , serine-threonine protein kinase N , serine/threonine protein kinase N , serine/threonine-protein kinase N1 , serine/threonine kinase 3 , protein kinase N1 , serine/threonine-protein kinase N1-like , protein kinase PKN , CG2049-PB , CG2049-PC , CG2049-PD , CG2049-PE , CG2049-PF , CG2049-PG , CG2049-PH , CG2049-PI , CG2049-PJ , CG2049-PK , CG2049-PL , CG2049-PM , Pkn-PB , Pkn-PC , Pkn-PD , Pkn-PE , Pkn-PF , Pkn-PG , Pkn-PH , Pkn-PI , Pkn-PJ , Pkn-PK , Pkn-PL , Pkn-PM , protein kinase N , protein kinase c related , protein kinase related to protein kinase N , protein kinase-like 45C

GENE ID SPECIES
5585 Homo sapiens
320795 Mus musculus
455785 Pan troglodytes
509080 Bos taurus
100007897 Danio rerio
100379847 Xenopus (Silurana) tropicalis
100401855 Callithrix jacchus
29355 Rattus norvegicus
35950 Drosophila melanogaster
100713234 Cavia porcellus
101118101 Ovis aries
100856398 Canis lupus familiaris
100515528 Sus scrofa
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