Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L Proteins (PPM1L)

PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. Additionally we are shipping PPM1L Antibodies (42) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPM1L 242083 Q8BHN0
Rat PPM1L PPM1L 310506  
PPM1L 151742 Q5SGD2
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Top PPM1L Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,493.38
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details

PPM1L Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
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More Proteins for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L) Interaction Partners

Mouse (Murine) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L) interaction partners

  1. Study provided evidence that PPM1L is involved in the development of the central nervous system.

  2. This study provides the first in vivo evidence that PP2Ce is an essential regulator of normal lactation, possibly involving IRE1 signaling and endoplasmic reticulum stress regulation in mammary epithelium.

  3. in the absence of IL-1-induced signal, PP2Cepsilon contributes to keeping the TAK1 signaling pathway in an inactive state by associating with and dephosphorylating TAK1.

  4. CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus.

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L) interaction partners

  1. identified ACBD3 as an interacting partner of PPM1L, and showed that this association, which recruits PPM1L to ER-Golgi membrane contact sites, is mediated by a GOLD (Golgi dynamics) domain in ACBD3

  2. Genetic variation at chromosome 3 harbors an element that regulates expression of an upstream candidate tumor suppressor, PPM1L, thus providing a novel mechanism for colorectal tumorigenesis.

  3. cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon*)

  4. These results suggest that PP2Cepsilon maintains ASK1 in an inactive state by dephosphorylation in quiescent cells, supporting the possibility that PP2Cepsilon and PP5 play different roles in H2O2-induced regulation of ASK1 activity.

  5. CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus.

PPM1L Protein Profile

Protein Summary

PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate stress-activated protein kinase (SAPK\; see MIM 601158) signaling cascades that respond to extracellular stimuli (Jin et al., 2004

Gene names and symbols associated with PPM1L

  • protein phosphatase 1 (formerly 2C)-like (Ppm1l)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1L (Ppm1l)
  • protein phosphatase, Mg2+/Mn2+ dependent 1L (PPM1L)
  • protein phosphatase, Mg2+/Mn2+ dependent 1L (Ppm1l)
  • protein phosphatase, Mg2+/Mn2+ dependent 1L L homeolog (ppm1l.L)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1La (ppm1la)
  • 3222401G13 protein
  • 5930404J21Rik protein
  • AI481720 protein
  • AW045850 protein
  • mKIAA4175 protein
  • PP2C protein
  • PP2C-epsilon protein
  • PP2CE protein
  • PP2Cepsilon protein
  • PPM1-LIKE protein
  • ppm1l protein
  • Ppp2ce protein
  • zgc:154091 protein

Protein level used designations for PPM1L

PP2C-epsilon , protein phosphatase 1-like , protein phosphatase 1L , protein phosphatase 2C epsilon , protein phosphatase 2C isoform epsilon , protein phosphatase 2a, catalytic subunit, epsilon isoform , PP2C epsilon , Protein phosphatase 2C epsilon isoform , protein phosphatase, Mg2+/Mn2+ dependent 1L L homeolog , protein phosphatase, Mg2+/Mn2+ dependent, 1L

GENE ID SPECIES
242083 Mus musculus
310506 Rattus norvegicus
151742 Homo sapiens
541235 Bos taurus
100729568 Cavia porcellus
494827 Xenopus laevis
556994 Danio rerio
Selected quality suppliers for PPM1L Proteins (PPM1L)
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