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Pyruvate Dehydrogenase Complex, Component X Proteins

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A.

9 results:

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 54-501) protein (His tag) Protein

PDHX Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3124972
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 54-501) protein (His tag) Protein

PDHX Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3085027
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 54-501) protein (His tag) Protein

PDHX Origin: Human Source: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Catalog No. ABIN5623929
$550.18
Plus shipping costs $45.00
20 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 1-109) protein (GST tag) Protein

PDHX Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1314527
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 220-468) protein (T7 tag,His tag) Protein

PDHX Origin: Human Source: Escherichia coli (E. coli) Recombinant ≥ 99 % ELISA, IP, SDS, WB
Catalog No. ABIN6238096
$436.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 222-471) protein (T7 tag,His tag) Protein

PDHX Origin: Mouse Source: Escherichia coli (E. coli) Recombinant ≥ 99 % ELISA, IP, SDS, WB
Catalog No. ABIN6238115
$466.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

PDHX Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2728549
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 54-501) protein (His tag) Protein

PDHX Origin: Human Source: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN6387533
$1,107.69
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 13 to 16 Business Days

Pyruvate Dehydrogenase Complex, Component X (PDHX) (AA 54-501) protein (His tag) Protein

PDHX Origin: Cow Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1459716
$3,256.00
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
  • Type Protein
    • Protein
  • Target Pyruvate Dehydrogenase Complex, Component X (PDHX)
    • Pyruvate Dehydrogenase Complex, Component X (PDHX)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
    • Ferrochelatase, HEMH (HEMH)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Cow
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • Insect Cells
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Binding Specificity
    • AA 54-501
    • AA 1-109
    • AA 220-468
    • AA 222-471
    • Transcript Variant 1
  • Conjugate
    • Un-conjugated
    • His tag
    • T7 tag,His tag
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

Pyruvate Dehydrogenase Complex, Component X (PDHX) Protein Profile

Protein Summary

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with PDHX

  • pyruvate dehydrogenase complex, component X (pdhx) antibody
  • pyruvate dehydrogenase complex component X (PDHX) antibody
  • pyruvate dehydrogenase complex component X L homeolog (pdhx.L) antibody
  • E3-binding protein (pdhX) antibody
  • pyruvate dehydrogenase complex component X (pdhx) antibody
  • pyruvate dehydrogenase complex, component X (Pdhx) antibody
  • Ac1164 antibody
  • AI481367 antibody
  • DDBDRAFT_0168431 antibody
  • DDBDRAFT_0230192 antibody
  • DDB_0168431 antibody
  • DDB_0230192 antibody
  • DLDBP antibody
  • E3bp antibody
  • MGC86218 antibody
  • OPDX antibody
  • PDHX antibody
  • Pdx1 antibody
  • proX antibody
  • zgc:66110 antibody
  • zgc:85977 antibody

Protein level used designations for PDHX

pyruvate dehydrogenase complex, component X , pyruvate dehydrogenase protein X component, mitochondrial-like , dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex , lipoyl-containing pyruvate dehydrogenase complex component X , pyruvate dehydrogenase complex, E3-binding protein subunit , pyruvate dehydrogenase complex, lipoyl-containing component X , pyruvate dehydrogenase protein X component, mitochondrial , dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX) , E3-binding protein , E3BP , proX , pyruvate dehydrogenase protein X component

GENE ID SPECIES
393532 Danio rerio
423154 Gallus gallus
447247 Xenopus laevis
451120 Pan troglodytes
8618072 Dictyostelium discoideum AX4
100059260 Equus caballus
100220979 Taeniopygia guttata
100349815 Oryctolagus cuniculus
100379696 Xenopus (Silurana) tropicalis
100455315 Pongo abelii
100475970 Ailuropoda melanoleuca
100544023 Meleagris gallopavo
100586539 Nomascus leucogenys
8050 Homo sapiens
27402 Mus musculus
311254 Rattus norvegicus
475942 Canis lupus familiaris
517402 Bos taurus

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