anti-RNA Binding Motif Protein 10 (RBM10) Antibodies

RBM10 encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. Additionally we are shipping RBM10 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RBM10 8241 P98175
RBM10 236732 Q99KG3
RBM10 64510 P70501
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Top anti-RBM10 Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Rabbit Anti-RBM10 Antibody       Paraffin Embedded Tissue:  Human cardiac cell   Cellular Data:  Epithelial cells of renal tubule  Antibody Concentration:   4.0-8.0 ug/ml  Magnification:   400X Rabbit Anti-RBM10 Antibody  Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of RBM10 Antibody (N-term) in 293 cell line lysates (35ug/lane). This demonstrates the RBM10 antibody detected the RBM10 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$493.17
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated WB Western blot analysis in 293 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using RBM10 antibody (ABIN1874563) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 100 μL 11 to 13 Days
$366.77
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using RBM10 antibody (ABIN5972338) at 1/1000 dilution. 100 μL 11 to 16 Days
$426.40
Details
Human Mouse Un-conjugated ELISA, WB   100 μg 11 to 14 Days
$551.83
Details

Top referenced anti-RBM10 Antibodies

  1. Human Polyclonal RBM10 Primary Antibody for EIA, WB - ABIN954474 : Johnston, Teer, Cherukuri, Hansen, Loftus, Chong, Mullikin, Biesecker: Massively parallel sequencing of exons on the X chromosome identifies RBM10 as the gene that causes a syndromic form of cleft palate. in American journal of human genetics 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal RBM10 Primary Antibody for ICC, IF - ABIN4349575 : Jackson, Du, Janesko-Feldman, Vagni, Dezfulian, Poloyac, Jackson, Clark, Kochanek: The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015 (PubMed)

More Antibodies against RBM10 Interaction Partners

Human RNA Binding Motif Protein 10 (RBM10) interaction partners

  1. we found that RBM10 activated key proliferative signaling pathways [such as the epidermal growth factor receptor (EGFR), mitogenactivated protein kinase (MAPK) and phosphoinositide 3kinase (PI3K)AKT pathways] and inhibited apoptotic pathways. In addition, we demonstrated that a high expression of RBM10 protein in patient tissue samples was associated with a shorter overall survival time and a poor prognosis

  2. RBM10 acts as a tumor suppressor in osteosarcoma. This could enable to define a new strategy for diagnosis and treatment of patients with osteosarcoma.

  3. RBM10: Harmful or helpful-many factors to consider.

  4. RBM10 mutations contribute to lung adenocarcinoma pathogenesis.

  5. The high rate of TERT promoter mutations, MED12 mutations, RBM10 mutations, and chromosome 1q gain highlight their likely association with tumor virulence

  6. The well-known high-fidelity RNA splice site recognition by RBM10, and probably by RBM5 and RBM6, can thus be largely rationalized by a cooperative binding action of RRM and ZnF domains

  7. Our work has not only expanded the number of pre-mRNA targets for RBM10, but identified RBM10 as a novel regulator of SMN2 alternative inclusion.

  8. RBM10 functions as a splicing regulator using two RNA-binding units with different specificities to promote exon skipping.

  9. RNA binding motif protein 10 (RBM10) negatively regulates its own mRNA and protein expression and that of RNA binding motif protein 5 (RBM5) by promoting alternative splicing-coupled nonsense-mediated mRNA decay (AS-NMD).

  10. results provide evidence that RBM10 expression, in RBM5-null tumors, may contribute to tumor growth and metastasis. Measurement of both RBM10 and RBM5 expression in clinical samples may therefore hold prognostic and/or potentially predictive value

  11. RBM10-TFE3 is a recurrent gene fusion in Xp11 translocation renal cell carcinoma.

  12. Xp11 translocation renal cell carcinomas with RBM10-TFE3 gene fusion demonstrating melanotic features and overlapping morphology with t(6;11) RCC.

  13. RNA-binding motif 10 messenger RNA and protein were reduced in lung adenocarcinoma tissues, and RNA-binding motif 10 overexpression inhibited lung adenocarcinoma cancer cell malignant behavior in vitro. Molecularly, RNA-binding motif 10 regulates many gene pathways involving in the tumor development or progression.

  14. RBM10-TFE3 fusion variant (from chromosome X paracentric inversion), therefore, appears to be a recurrent molecular event in Xp11.2 RCCs. RBM10-TFE3 fusion should be added in the list of screened fusion transcripts in targeted molecular diagnostic multiplex RT-PCR

  15. RBM10 is a tumor suppressor that represses Notch signaling and cell proliferation through the regulation of NUMB alternative splicing

  16. Src family tyrosine kinase signaling may regulate FilGAP through association with RBM10

  17. The ability of RBM10v1 to regulate alternative splicing depends, at least in part, on a structural alteration within the second RNA recognition motif domain, and correlates with preferential expression of the NUMB exon 11 inclusion variant.

  18. RBM10 regulates alternative splicing of Fas and Bcl-x genes.

  19. Antagonizes the effects of RBM5, RBM6, and RBM10 in cell colony formation.

  20. This study established RBM10 as an important regulator of alternative splicing, presented a mechanistic model for RBM10-mediated splicing regulation and provided a molecular link to understanding a human congenital disorder.

Mouse (Murine) RNA Binding Motif Protein 10 (RBM10) interaction partners

  1. this study shows that Rbm10 regulates inflammation development via alternative splicing of Dnmt3b

  2. These results demonstrate a role for RBM10 in the regulation of alternative splicing in two cell models of mouse early development and suggests that mutations in RBM10 could lead to splicing changes that affect normal palate development and cause human disease.

  3. Expression of Rbm5 and Rbm10 RNA remained constant during C2C12 myogenesis, but protein levels significantly decreased.

  4. S1-1 constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner; upon globally reducing RNA polymerase II transcription, S1-1 nuclear bodies enlarge and decrease in number.

RBM10 Antigen Profile

Protein Summary

This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with RBM10

  • RNA binding motif protein 10 (RBM10) antibody
  • RNA binding motif protein 10 (rbm10) antibody
  • RNA binding motif protein 10 (Rbm10) antibody
  • DXS8237E antibody
  • E430039K10Rik antibody
  • GPATC9 antibody
  • GPATCH9 antibody
  • RBM10 antibody
  • S1-1 antibody
  • TARPS antibody
  • ZRANB5 antibody

Protein level used designations for RBM10

RNA binding motif protein 10 , RNA-binding protein 10-like , RNA-binding protein 10 , RNA-binding protein S1-1 , g patch domain-containing protein 9 , RNA-binding motif protein 10 , S1-1 protein from liver

GENE ID SPECIES
505749 Bos taurus
711791 Macaca mulatta
100018039 Monodelphis domestica
100339934 Oryctolagus cuniculus
100524537 Sus scrofa
100564045 Anolis carolinensis
100594619 Nomascus leucogenys
8241 Homo sapiens
480895 Canis lupus familiaris
236732 Mus musculus
64510 Rattus norvegicus
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