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RBM17 encodes an RNA binding protein.
Showing 10 out of 28 products:
this work provides the structural and molecular basis of the interaction between RBM17 and the phosphorylated form of ATXN1 (show ATXN1 Antibodies).
identify SPF45 as the first splicing factor (show SLU7 Antibodies) regulated by multiple MAP kinase (show MAPK1 Antibodies) pathways and show effects of both SPF45 overexpression and phosphorylation
dephosphorylation of pS776-ATXN1 (show ATXN1 Antibodies) by PP2A (show PPP2R4 Antibodies) regulates the interaction of ATXN1 (show ATXN1 Antibodies) with the splicing factors RBM17 and U2AF65 (show U2AF59 Antibodies)
overexpression of SPF45 in HeLa, a cervical carcinoma cell line, resulted in drug resistance to doxorubicin and vincristine
The SPF45 regulates alternative splicing of the apoptosis regulatory gene CD95 (show FAS Antibodies); 2.1-A crystal structure of SPF45-UHM in complex with a ULM peptide from SF3b155 (show SF3B1 Antibodies) is reported.
Resistance to various chemotherapeutics resulting from stable transfection of RBM17 (SPF45) in A2780 ovarian carcinoma cells may be due to effects of SPF45 on transcription and splicing of ERbeta (show ESR2 Antibodies)-regulated genes.
we found a significant overlap in genes that undergo both RBM17- and TDP-43 (show TARDBP Antibodies)-dependent cryptic splicing repression, many of which are associated with survival. We propose that repression of cryptic splicing by RBPs is critical for neuronal health and survival
dephosphorylation of pS776-ATXN1 (show ATXN1 Antibodies) by PP2A (show PPP2R2B Antibodies) regulates the interaction of ATXN1 (show ATXN1 Antibodies) with the splicing factors RBM17 and U2AF65 (show U2AF59 Antibodies)
This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15.
splicing factor 45
, RNA binding motif protein 17
, 45 kDa-splicing factor
, splicing factor 45-like
, RNA-binding motif protein 17
, splicing factor 45kDa