RNA Binding Motif Protein 8A Proteins (RBM8A)

RBM8A encodes a protein with a conserved RNA-binding motif.

list all proteins	Gene Name	GeneID	UniProt
Human RBM8A	RBM8A	9939	Q9Y5S9
Mouse RBM8A	RBM8A	60365	Q9CWZ3
Rat RBM8A	RBM8A	295284	Q27W01

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Top RNA Binding Motif Protein 8A Proteins at antibodies-online.com

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Catalog No.	Origin	Source	Conjugate	Quantity	Supplier	Delivery	Price	Details
ABIN3094969	Escherichia coli (E. coli)	Human	His tag	1 mg	Log in to see	30 to 35 Days	$4,744.22	Details
ABIN3137050	Escherichia coli (E. coli)	Mouse	His tag	1 mg	Log in to see	30 to 35 Days	$4,744.22	Details
ABIN1317629	Wheat germ	Human	GST tag	10 μg	Log in to see	11 to 12 Days	$414.29	Details
ABIN2730625	HEK-293 Cells	Human	Myc-DYKDDDDK Tag	20 μg	Log in to see	Available	$814.00	Details
ABIN666630	Escherichia coli (E. coli)	Human	His tag	50 μg	Log in to see	15 to 19 Days	$492.31	Details
ABIN1629154	Yeast	Cow	His tag	1 mg	Log in to see	60 to 71 Days	$2,401.67	Details
ABIN1620712	Yeast	Rat	His tag	1 mg	Log in to see	60 to 71 Days	$2,401.67	Details
ABIN1633545	Yeast	Zebrafish	His tag	1 mg	Log in to see	60 to 71 Days	$2,405.33	Details
ABIN1621950	Yeast	Xenopus tropicalis	His tag	1 mg	Log in to see	60 to 71 Days	$2,405.33	Details
ABIN1655522	Yeast	REACT_Atlantic Salmon	His tag	1 mg	Log in to see	60 to 71 Days	$2,409.00	Details

More product categories related to RNA Binding Motif Protein 8A Protein

More Proteins for RNA Binding Motif Protein 8A (RBM8A) Interaction Partners

Human RNA Binding Motif Protein 8A (RBM8A) interaction partners

Results demonstrated that RBM8A is highly expressed in hepatocellular carcinoma (HCC (show FAM126A Proteins)), and patients with lower RBM8A expression level had longer overall survival and progression free survival. Also, results indicate that RBM8A promotes invasion and metastasis via epithelial-mesenchymal transition signaling pathway.
Y14 may selectively and differentially modulate protein biosynthesis.
this data suggests a novel role of RBM8a in the regulation of neurodevelopment.
Mutations of RBM8A and TBX6 (show TBX6 Proteins) are associated with disorders of the mullerian ducts.
It was demonstrated that Rbm8a is an essential neurogenesis regulator in embryonic cortical development.
Depletion of RNA-binding protein (show PTBP1 Proteins) RBM8A (Y14) causes cell cycle deficiency and apoptosis in human tumor cells.
Y14 positively regulates signals for TNF-alpha (show TNF Proteins)-induced IL-6 (show IL6 Proteins) production at multiple steps beyond an exon junction complex protein.
Y14 mutants, which are deficient in binding to Magoh (show MAGOH Proteins), could still be localized to the nucleus, suggesting the existence of both the nuclear import pathway and function for Y14 unaccompanied by Magoh (show MAGOH Proteins)
Data show that Y14 interacts directly with the decapping factor Dcp2 (show DCP2 Proteins) and the 5' cap structure of mRNAs via different but overlapping domains.
findings show that the two regulatory SNPs result in diminished RBM8A transcription in vitro and that Y14 expression is reduced in platelets from individuals with thrombocytopenia with absent radii (TAR)

Mouse (Murine) RNA Binding Motif Protein 8A (RBM8A) interaction partners

our data demonstrate that miR (show MLXIP Proteins)-29a regulates the proliferation and differentiation of RPCs by directly targeting Rbm8a, providing us with a better understanding of the molecular mechanisms that govern RPC (show RTCD1 Proteins) proliferation and differentiation.
Data suggest that, in embryonic stem cells, Gsk3b/Gsk3a (show GSK3a Proteins) phosphorylate splicing factors (Rbm8a, Srsf9 (show SFRS9 Proteins), and Psf (show IL-3 Proteins)) and nucleolar proteins (Npm1 (show GJA1 Proteins) and Phf6 (show PHF6 Proteins)); Gsk3b/Gsk3a (show GSK3a Proteins) are key to alternative splicing of close to 190 genes. (Gsk3 = glycogen synthase kinase-3 (show GSK3a Proteins); Rbm8a = RNA binding motif protein 8a; Srsf9 (show SFRS9 Proteins) = splicing factor (show SLU7 Proteins), arginine-serine-rich 9; Psf (show IL-3 Proteins) = replication protein Psf (show IL-3 Proteins); Npm1 (show GJA1 Proteins) = nucleophosmin 1 (show NPM1 Proteins); Phf6 (show PHF6 Proteins) = PHD finger protein 6 (show PHF6 Proteins))
we first show that Eif4a3 (show EIF4A3 Proteins) haploinsufficiency phenocopies aberrant neurogenesis and microcephaly of Magoh (show MAGOH Proteins) and Rbm8a mutant mice.we show that genetic ablation of one downstream pathway, p53 (show TP53 Proteins), significantly rescues microcephaly of all 3 EJC mutant
this data suggests a novel role of RBM8a in the regulation of neurodevelopment.
This is the first study that demonstrates the key role of RBM8a on the emotional behaviors in mice.

RNA Binding Motif Protein 8A (RBM8A) Protein Profile

Protein Summary

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B\; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

Gene names and symbols associated with RBM8A

RNA binding motif protein 8A (RBM8A)
RNA binding motif protein 8A (rbm8a)
RNA binding motif protein 8a (Rbm8a)
RNA binding motif protein 8A (Rbm8a)
RNA binding motif protein 8A S homeolog (rbm8a.S)

2310057C03Rik protein
AA673428 protein
BOV-1A protein
BOV-1B protein
BOV-1C protein
C1DELq21.1 protein
DEL1q21.1 protein
fb34f03 protein
MDS014 protein
Rbm8 protein
rbm8-A protein
rbm8a protein
rbm8a-A protein
RBM8B protein
rnp-5 protein
TAR protein
wu:fb34f03 protein
Y14 protein
zgc:110525 protein
ZNRP protein
ZRNP1 protein

Protein level used designations for RBM8A

RNA binding motif protein 8A , RNA-binding motif protein 8A , RNA-binding protein 8A , Ribonucleoprotein RBM8A , RNA binding motif protein 8B , BOV-1 , RNA-binding protein Y14 , binder of OVCA1-1 , ribonucleoprotein RBM8 , ribonucleoprotein RBM8A , RNA binding motif protein 8 , RNA-binding motif protein 8A-A , RNA-binding protein 8A-A , Ribonucleoprotein RBM8A-A

GENE ID	SPECIES
457983	Pan troglodytes
733972	Xenopus (Silurana) tropicalis
100034052	Equus caballus
100356723	Oryctolagus cuniculus
100049229	Oryzias latipes
9939	Homo sapiens
503767	Danio rerio
475827	Canis lupus familiaris
518045	Bos taurus
60365	Mus musculus
295284	Rattus norvegicus
100196667	Salmo salar
399167	Xenopus laevis

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