anti-Ras Association (RalGDS/AF-6) and Pleckstrin Homology Domains 1 (RAPH1) Antibodies

Mediator of localized membrane signals. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAPH1 65059 Q70E73
RAPH1    
RAPH1    
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Top anti-Ras Association (RalGDS/AF-6) and Pleckstrin Homology Domains 1 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of RAPH1 expression in HepG2 (A), H9C2 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of RAPH1 using 293 whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL 11 to 13 Days
$335.04
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using RAPH1 antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of human skin with RAPH1 polyclonal antibody  shows strong cytoplasmic positivity in epidermal cells at 1:10-1:20 dilution. 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated WB   100 μL 9 to 11 Days
$281.29
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB   100 μg 13 to 16 Days
$430.77
Details
Human Rabbit Un-conjugated ELISA, IF/ICC, IHC, WB   100 μg 11 to 18 Days
$568.54
Details
Human Rabbit Biotin   100 μL 2 to 3 Days
$394.90
Details

Top referenced anti-Ras Association (RalGDS/AF-6) and Pleckstrin Homology Domains 1 Antibodies

  1. Human Polyclonal RAPH1 Primary Antibody for IHC, IHC (p) - ABIN4349375 : Boucrot, Ferreira, Almeida-Souza, Debard, Vallis, Howard, Bertot, Sauvonnet, McMahon: Endophilin marks and controls a clathrin-independent endocytic pathway. in Nature 2015 (PubMed)

More Antibodies against Ras Association (RalGDS/AF-6) and Pleckstrin Homology Domains 1 Interaction Partners

Human Ras Association (RalGDS/AF-6) and Pleckstrin Homology Domains 1 (RAPH1) interaction partners

  1. High RAPH1 expression is correlated with aggressive breast cancer phenotypes and provides independent prognostic value in invasive breast cancer.

  2. The human RAPH1 gene is the CHE2 locus.

  3. these studies demonstrate an insight into how the Lpd-PH domain regulates cellular signals in a PI(3,4)P2 dependent manner.

  4. Disruption of the RIAM/lamellipodin-integrin-talin complex markedly impairs cell migration.

  5. The authors propose that Lpd delivers Ena/VASP proteins to growing barbed ends and increases their actin polymerase activity by tethering them to actin filaments.

  6. These data indicate a possible role for Lpd in the actin-based movement and the cell-to-cell spread of L. monocytogenes.

  7. The results suggest that although the RAPH1 gene was deleted or amplified in all samples, the Lpd does not seem to play a major role in tumorigenesis of mammary carcinomas.

  8. this study suggests a novel mechanism in which Lpd mediates EGFR endocytosis via Mena downstream of endophilin.

  9. The crystal structure of Lpd cc-RA-PH presents a molecular model of Lpd enhances actin polymerization by oligomerization via two intermolecular contact sites.

  10. results of this study suggested that that PI(3,4)P2, Lpd, and Ena/VASP are involved in the process movement of multipolar migrating cells.

  11. Nephrin ligation resulted in abnormal morphology of actin tails in human podocytes when Ship2, Filamin or Lamellipodin were individually knocked down.

  12. Data show that profilin1 negatively regulates lamellipodin targeting to the leading edge; profilin1 depletion increases lamellipodin concentration at the lamellipodial tip (where it binds Ena/VASP), and this mediates the hypermotility.

  13. RMO1 is expressed and deleted in osteosarcoma

  14. proline-rich peptides organize the 4 subunits of BChE into a 340 kDa tetramer, by interacting with the C-terminal BChE tetramerization domain

  15. Consistently, in HeLa cells, lamellipodin was required for EGF-induced proliferation.

Ras Association (RalGDS/AF-6) and Pleckstrin Homology Domains 1 (RAPH1) Antigen Profile

Protein Summary

Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.

Gene names and symbols associated with RAPH1

  • Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (RAPH1) antibody
  • ALS2CR9 antibody
  • ALS2CR18 antibody
  • LPD antibody
  • PREL-2 antibody
  • PREL2 antibody
  • RalGDS/AF-6 antibody
  • RMO1 antibody

Protein level used designations for RAPH1

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18 , amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9 , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein , lamellipodin , proline-rich EVH1 ligand 2 , ras-associated and pleckstrin homology domains-containing protein 1

GENE ID SPECIES
65059 Homo sapiens
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