anti-Regenerating Islet-Derived Family, Member 4 (REG4) Antibodies

Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. Additionally we are shipping REG4 Kits (57) and REG4 Proteins (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
REG4 445583 Q68AX7
REG4 83998 Q9BYZ8
REG4 67709 Q9D8G5
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Top anti-REG4 Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of REG4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. w Western blot analysis of REG4 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 13 to 16 Days
$332.00
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$163.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Antigen: 0.2ug/100ul, Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in MicroplateReader by 450nm 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of REG4 using HeLa whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Reg4 Antibody [NBP2-38552] - Staining of human small intestine shows strong cytoplasmic positivity in goblet cells. Immunohistochemistry-Paraffin: Reg4 Antibody  - Staining of human liver shows low expression as expected. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$273.90
Details
Human Rabbit Biotin WB   100 μL Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit FITC WB   100 μL Log in to see 7 to 9 Days
$566.50
Details

More Antibodies against REG4 Interaction Partners

Human Regenerating Islet-Derived Family, Member 4 (REG4) interaction partners

  1. Reg4 inhibited apoptosis through regulating MAPK/Erk (show MAPK1 Antibodies)/Bim (show BCL2L11 Antibodies) signaling pathway and thereby enhanced the resistance of gastric cancer to 5-Fluorouracil.

  2. Data indicate that REG4 tissue expression is a prognostic marker in subgroups of pancreatic ductal adenocarcinoma patients, and Serum REG4 level might be useful in differential diagnosis between pancreatic ductal adenocarcinoma and chronic pancreatitis.

  3. REG4 promotes peritoneal metastasis of gastric cancer through GPR37 (show GPR37 Antibodies) and triggers a positive feedback loop.

  4. Study demonstrated that REG4, which is overexpressed in pancreatic ductal adenocarcinoma and secreted by cancer cells, promoted macrophage polarization to M2, through at least in part, activation of ERK1/2 and CREB (show CREB1 Antibodies).

  5. REG4 is a transcriptional target of GATA6 (show GATA6 Antibodies) and is essential for colorectal tumorigenesis.

  6. This study identifies REG4 as a potential serum biomarker for histotype-specific detection of mucinous ovarian cancer and suggests serum REG4 measurement as a non-invasive diagnostic tool for follow-up of patients with mucinous ovarian cancer.

  7. aberrant REG4 expression plays an essential role in early ovarian carcinogenesis and is closely linked to mucinous ovarian tumors, differentiation and adverse prognosis of ovarian cancer by modulating proliferation, apoptosis, migration and invasion.

  8. REG4 expression associated with favorable clinicopathological parameters and with higher overall survival from non-mucinous

  9. The Reg IV may be involved in the finetuning of functions exerted by the neuroendocrine cells in the GI-tract.

  10. Colorectal tumor patients with Reg4- and MMP-7 (show MMP7 Antibodies)-positive tumors had extremely poor overall survival.

Mouse (Murine) Regenerating Islet-Derived Family, Member 4 (REG4) interaction partners

  1. sorted Reg4(+) DCS cells promote organoid formation of single Lgr5 (show LGR5 Antibodies)(+) colon stem cells. DCS cells can be massively produced from Lgr5 (show LGR5 Antibodies)(+) colon stem cells in vitro by combined Notch (show NOTCH1 Antibodies) inhibition and Wnt (show WNT2 Antibodies) activation

  2. data suggest that Reg4 may protect against acinar cell necrosis in experimental pancreatitis by enhancing the expression of Bcl-2 (show BCL2 Antibodies) and Bcl-xL (show BCL2L1 Antibodies) via activation of the EGFR (show EGFR Antibodies)/Akt (show AKT1 Antibodies) signalling pathway.

  3. Reg IV as an important modulator of gastrointestinal cell susceptibility to irradiation; hence, it is a potential target for adjunctive treatments for human colorectal cancer and other gastrointestinal malignancies.

  4. reg4 is amplified in the early stages of pancreatic cancer development

  5. Cloning and characterization of human REG4/RELP, in addition to cloning of mouse Reg4.

REG4 Antigen Profile

Protein Summary

Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium (By similarity).

Gene names and symbols associated with REG4

  • regenerating family member 4 (Reg4) antibody
  • regenerating family member 4 (REG4) antibody
  • regenerating islet-derived family, member 4 (Reg4) antibody
  • 2010002L15Rik antibody
  • GISP antibody
  • REG-IV antibody
  • RELP antibody

Protein level used designations for REG4

REG-4 , regenerating islet-derived protein 4 , REG-like protein , gastrointestinal secretory protein , reg IV , regenerating gene type IV , regenerating islet-derived protein IV

GENE ID SPECIES
445583 Rattus norvegicus
83998 Homo sapiens
67709 Mus musculus
100154580 Sus scrofa
767907 Bos taurus
100727547 Cavia porcellus
424379 Gallus gallus
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