Regulation of Nuclear Pre-mRNA Domain Containing 1B Proteins

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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  • 1
Application
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  • 1
Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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7 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3095124
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3128483
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % pure
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5623660
$440.14
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1318717
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731158
$504.90
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Human Cells (Source), Purity > 85 % as determined by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2650328
$505.35
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5854183
$553.85
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
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Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) Protein Profile

Protein Summary

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation (By similarity).

Gene names and symbols associated with RPRD1B

  • regulation of nuclear pre-mRNA domain containing 1B (rprd1b) antibody
  • regulation of nuclear pre-mRNA domain containing 1B L homeolog (rprd1b.L) antibody
  • regulation of nuclear pre-mRNA domain containing 1B (RPRD1B) antibody
  • regulation of nuclear pre-mRNA domain containing 1B (Rprd1b) antibody
  • 2610304G08Rik antibody
  • 2810446G03Rik antibody
  • C13H20ORF77 antibody
  • C20orf77 antibody
  • Crept antibody
  • dJ1057B20.2 antibody
  • fb23h08 antibody
  • MGC130705 antibody
  • NET60 antibody
  • RGD1304782 antibody
  • rprd1ba antibody
  • wu:fb23h08 antibody
  • zgc:55687 antibody

Protein level used designations for RPRD1B

regulation of nuclear pre-mRNA domain-containing protein 1B , unm hi3400 , un-named hi3400 , regulation of nuclear pre-mRNA domain containing 1B , regulation of nuclear pre-mRNA domain containing 1B a , Regulation of nuclear pre-mRNA domain containing 1B , cell cycle-related and expression-elevated protein in tumor , cell-cycle related and expression-elevated protein in tumor

GENE ID SPECIES
321636 Danio rerio
446428 Xenopus laevis
469936 Pan troglodytes
485866 Canis lupus familiaris
529700 Bos taurus
100029442 Monodelphis domestica
100055539 Equus caballus
100190582 Taeniopygia guttata
100380115 Xenopus (Silurana) tropicalis
100606473 Nomascus leucogenys
58490 Homo sapiens
70470 Mus musculus
419295 Gallus gallus
311591 Rattus norvegicus
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