Retinal Outer Segment Membrane Protein 1 Proteins (ROM1)

ROM1 is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. Additionally we are shipping ROM1 Antibodies (32) and ROM1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ROM1 6094 Q03395
Rat ROM1 ROM1 309201 Q5PPM7
ROM1 19881 P32958
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Top ROM1 Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 14 to 16 Days
$437.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
Escherichia coli (E. coli) Mouse Un-conjugated SDS-PAGE analysis of Mouse ROM1 Protein. 100 μg Log in to see 11 to 18 Days
$540.11
Details
Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$654.29
Details

ROM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Retinal Outer Segment Membrane Protein 1 (ROM1) Interaction Partners

Human Retinal Outer Segment Membrane Protein 1 (ROM1) interaction partners

  1. our study unravels unexpected opposing roles of per(WT) and Rom-1 in rod outer segment (OS)targeting of adRP-linked peripherin-2 mutants and suggests a new treatment strategy for the affected individuals.

  2. ablation of Rom1 results in the conversion of an MD/PD phenotype characterized by cone functional defects and the formation of abnormal Prph2/Rom1 complexes to an RP phenotype characterized by rod-dominant functional defects and reductions in total Prph2 protein. Thus one method by which ROM1 may act as a disease modifier is by contributing to the large variability in PRPH2-associated disease phenotype

  3. Families showing a variable macular dystrophy phenotype caused by mutations in PRPH2 should be tested for additional mutations in ABCA4 and ROM1, as they may alter the progression of the PRPH2 phenotype.

Mouse (Murine) Retinal Outer Segment Membrane Protein 1 (ROM1) interaction partners

  1. ablation of Rom1 results in the conversion of an MD/PD phenotype characterized by cone functional defects and the formation of abnormal Prph2/Rom1 complexes to an RP phenotype characterized by rod-dominant functional defects and reductions in total Prph2 protein. Thus one method by which ROM1 may act as a disease modifier is by contributing to the large variability in PRPH2-associated disease phenotype

  2. ROM1 overexpression leads to negative effects on cone outer segments ultrastructure and function.

  3. The results suggested that Trp182Arg mutant Rom1 causes a decrease in the levels of wild-type Prph2 and Rom1.

ROM1 Protein Profile

Protein Summary

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.

Gene names and symbols associated with ROM1

  • retinal outer segment membrane protein 1 (ROM1)
  • retinal outer segment membrane protein 1 (Rom1)
  • rod outer segment membrane protein 1 (Rom1)
  • retinal outer segment membrane protein 1 L homeolog (rom1.L)
  • retinal outer segment membrane protein 1a (rom1a)
  • M101156 protein
  • rds35 protein
  • Rgsc1156 protein
  • rom protein
  • Rom-1 protein
  • ROM1 protein
  • rosp1 protein
  • RP7 protein
  • tspan23 protein
  • zgc:73336 protein
  • zgc:77401 protein

Protein level used designations for ROM1

rod outer segment membrane protein 1 , tetraspanin-23 , tspan-23 , ROSP1 , retinal outer segment membrane protein 1 , retinal outer membrane protein 1 , RDS/peripherin-like protein xRDS35 , rds/peripherin , rod outer segment protein 1 , peripherin-2

GENE ID SPECIES
6094 Homo sapiens
281465 Bos taurus
309201 Rattus norvegicus
466636 Pan troglodytes
483786 Canis lupus familiaris
100426294 Macaca mulatta
19881 Mus musculus
379513 Xenopus laevis
100063558 Equus caballus
100732195 Cavia porcellus
100350532 Oryctolagus cuniculus
393767 Danio rerio
Selected quality suppliers for ROM1 Proteins (ROM1)
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