RPE65 Proteins

RPE65 encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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  • 1
Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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5 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3095121
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3136848
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731119
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityCow (Bovine), Human, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN2751320
$318.85
5 applications
Plus shipping costs $45.00
Delivery in 1 to 2 Business Days
ReactivityRat (Rattus)
Application ELISA
Order details Cat. No. ABIN1475648
$3,518.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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RPE65 Protein Profile

Protein Summary

This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa.

Gene names and symbols associated with RPE65

  • RPE65, retinoid isomerohydrolase (RPE65) antibody
  • retinal pigment epithelium 65 (Rpe65) antibody
  • neither inactivation nor afterpotential B (ninaB) antibody
  • RPE65, retinoid isomerohydrolase (Rpe65) antibody
  • retinal pigment epithelium-specific protein 65kDa S homeolog (rpe65.S) antibody
  • retinal pigment epithelium-specific protein 65kDa L homeolog (rpe65.L) antibody
  • RPE65 homolog (rpe65) antibody
  • retinal pigment epithelium-specific protein 65kDa (rpe65) antibody
  • retinal pigment epithelium-specific protein 65c (rpe65c) antibody
  • retinal pigment epithelium-specific protein 65a (rpe65a) antibody
  • 65kDa antibody
  • A930029L06Rik antibody
  • anon-WO0148162.1 antibody
  • anon-WO0148163.1 antibody
  • beta-diox antibody
  • CG9347 antibody
  • DmelCG9347 antibody
  • DRPE65 antibody
  • LCA2 antibody
  • MGC52887 antibody
  • MGC85437 antibody
  • MGC154296 antibody
  • Mord1 antibody
  • mRPE65 antibody
  • rd12 antibody
  • RP20 antibody
  • RPE56a antibody
  • RPE56c antibody
  • rpe65 antibody
  • rpepa antibody
  • si:ch211-198n5.12 antibody
  • sRPE65 antibody
  • zgc:73213 antibody

Protein level used designations for RPE65

RBP-binding membrane protein , all-trans-retinyl-palmitate hydrolase , p63 , retinal pigment epithelium-specific 65 kDa protein , retinitis pigmentosa 20 (autosomal recessive) , retinoid isomerohydrolase , retinol isomerase , modifier of retinal degeneration 1 , retinal pigment epithelium, 65 kDa , neither inactivation nor afterpotential B , CG9347-PA , ninaB-PA , beta-carotene dioxygenase , retinal pigment epithelium 65-like , retinal pigment epithelium-specific protein (65kD) , retinal pigment epithelium-specific protein 65kDa , retinal pigment epithelium abundant protein RPE65 , rpe65 gene for retinal pigment epithelium-specific protein , RPE65 homolog , retinoid isomerohydrolase-like , All-trans-retinyl ester 13-cis isomerohydrolase C , All-trans-retinylester 11-cis isomerohydrolase C , Retinal pigment epithelium-specific 65 kDa protein homolog C , retinal Mueller cells isomerohydrolase , All-trans-retinylester 11-cis isomerohydrolase A , Retinal pigment epithelium-specific 65 kDa protein homolog A , all-trans-retinylester 11-cis isomerohydrolase A , retinal pigment epithelium 65a , retinal pigment epithelium-specific 65 kDa protein homolog A , retinal pigment epithelium-specific protein a

GENE ID SPECIES
6121 Homo sapiens
19892 Mus musculus
41678 Drosophila melanogaster
89826 Rattus norvegicus
282043 Bos taurus
379961 Xenopus laevis
395700 Gallus gallus
403803 Canis lupus familiaris
447613 Xenopus laevis
701764 Macaca mulatta
744567 Pan troglodytes
778842 Ciona intestinalis
100145692 Xenopus (Silurana) tropicalis
100397525 Callithrix jacchus
100453879 Pongo abelii
100516743 Sus scrofa
100588685 Nomascus leucogenys
100004076 Danio rerio
100219959 Taeniopygia guttata
100352270 Oryctolagus cuniculus
100721944 Cavia porcellus
393724 Danio rerio