Ribonuclease, RNase A Family, 7 Proteins (RNASE7)

RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002 [PubMed 12244054]\\\\; Zhang et al., 2003 [PubMed 12527768]).[supplied by OMIM, Dec 2008].. Additionally we are shipping RNASE7 Antibodies (19) and RNASE7 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNASE7 84659 Q9H1E1
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Top RNASE7 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 13 to 16 Days
$492.31
Details
Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 18 Days
$723.00
Details

RNASE7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Ribonuclease, RNase A Family, 7 (RNASE7) Interaction Partners

Human Ribonuclease, RNase A Family, 7 (RNASE7) interaction partners

  1. RNase 7 exhibits potent immunomodulatory functions and supports the efficient recognition of microbial infections by human skin-infiltrating pDCs.

  2. These data suggest that the induction of RNase 7 in response to Mycobacterium tuberculosis could have a role in anti-mycobacterial immunity.

  3. RNase 7 has immunomodulatory functions on TH2 cells and decreases the production of TH2 cytokines in the skin.

  4. Our results indicate that RNase 7 is an important factor released by keratinocytes to control the growth of P. aeruginosa on the skin surface.

  5. Insulin and PI3K/AKT signaling are essential for RNase 7 expression and increased infection risks in diabetic patients may be secondary to suppressed RNase 7 production.

  6. This article provides an overview about the role of RNase 7 in cutaneous defense with focus on the molecular mechanism of the antimicrobial activity of RNase 7, the regulation of RNase 7 expression, and the role of RNase 7 in skin diseases. [review]

  7. RNH1 bound to RNase 7 and suppressed its antimicrobial activity by blocking its ability to bind the cell wall of uropathogenic bacteria.

  8. epidermal growth factor-dependent RNase 7 and human beta-defensin-3 expression upon infection with Trichophytum rubrum

  9. RNase 7 is an antimicrobial protein that plays an important role in the innate immune defense system of human epithelia.

  10. Suggest that RNase 7 may function as antimicrobial peptide with a role in the differentiation and development of the primitive epidermis.

  11. Levels of psoriasin, RNase 7 and hBD-3 expression - assessed by immunohistochemistry - varied between different body localisations.

  12. the influence of STAT3 on the IL-17A/IFN-gamma -mediated RNase 7 induction

  13. RNase 7 expression is increased in the urinary tract with infection and has antibacterial activity against uropathogens at micromolar concentrations.

  14. a complex relationship between tear induction of miR-762, its modulation of innate defense genes, and P. aeruginosa internalization

  15. RNASE7 prevents staphylococcal skin infections

  16. proteases contribute indirectly to the defense function of the stratum corneum by releasing the RNase inhibitor mediated inhibition of RNase 5 and RNase 7.

  17. Using phospholipid vesicles as membrane models, RNase 3 triggers first the vesicle aggregation, while RNase 7 induces leakage well before the aggregation step.

  18. data indicate that RNase 7 contributes to the E. faecium-killing activity of skin extracts and suggest an important role for RNase 7 in the protection of human skin against E. faecium colonization

  19. These findings suggest that antimicrobial peptides found at high baseline levels in healthy skin, such as RNase 7, confer protection against Staphylococcus aureus infection of the skin.

RNASE7 Protein Profile

Protein Summary

RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002

Gene names and symbols associated with RNASE7

  • ribonuclease A family member 7 (RNASE7)

Protein level used designations for RNASE7

RNase 7 , SAP-2 , ribonuclease 7 , skin-derived antimicrobial protein 2

GENE ID SPECIES
84659 Homo sapiens
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