RRP8 Proteins

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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7 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3095127
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3137122
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1308572
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731214
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
ReactivitySchizosaccharomyces pombe
Application ELISA
Order details Cat. No. ABIN1617779
$2,852.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
ReactivityYeast (Saccharomyces cerevisiae)
Application ELISA
Order details Cat. No. ABIN1478090
$3,081.83
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
ReactivityRat (Rattus)
Application ELISA
Order details Cat. No. ABIN1635082
$3,285.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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RRP8 Protein Profile

Protein Summary

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

Gene names and symbols associated with RRP8

  • ribosomal RNA processing 8 (RRP8) antibody
  • ribosomal RNA processing 8, methyltransferase, homolog (yeast) (Rrp8) antibody
  • ribosomal RNA processing 8 (Rrp8) antibody
  • 1500003O22Rik antibody
  • 2900001K19Rik antibody
  • AW538116 antibody
  • KIAA0409 antibody
  • RGD1308302 antibody

Protein level used designations for RRP8

RRP8 methyltransferase homolog , cerebral protein 1 , nucleomethylin , ribosomal RNA-processing protein 8 , cerebral protein 1 homolog

GENE ID SPECIES
23378 Homo sapiens
101867 Mus musculus
308911 Rattus norvegicus
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