Ring Finger Protein 41 Proteins (RNF41)

RNF41 encodes an E3 ubiquitin ligase. Additionally we are shipping RNF41 Antibodies (47) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF41 10193 Q9H4P4
RNF41 67588 Q8BH75
Rat RNF41 RNF41 362814  
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Top RNF41 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days

RNF41 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Ring Finger Protein 41 (RNF41) Interaction Partners

Human Ring Finger Protein 41 (RNF41) interaction partners

  1. Data (including data from studies using knockout and transgenic mice/cells) suggest that CLEC16A, NRDP1, and USP8 (show USP8 Proteins) form tripartite complex; CLEC16A-NRDP1-USP8 (show USP8 Proteins) complex appears to rely on ubiquitin signals to promote mitophagy and maintain mitochondrial function necessary for beta-cell function. (CLEC16A = C-type lectin domain family 16 member A; NRDP1 = ubiquitin-protein ligase (show UBE2K Proteins) NRDP1; USP8 (show USP8 Proteins) = ubiquitin specific peptidase 8 (show USP8 Proteins))

  2. Over-expression of miR (show MLXIP Proteins)-497 promotes the proliferation of glioma cells U87 by targeting Nrdp1.

  3. Authors conclude that the planar cell polarity (PCP (show PRCP Proteins)) pathway contributes significantly to the motility and hence the invasiveness of glioblastoma multiforme (GBM) cells, and that Nrdp1 acts as a negative regulator of PCP (show PRCP Proteins) signaling by inhibiting Dvl (show DVL2 Proteins) through a novel polyubiquitination mechanism.

  4. Data suggest that PHLPP1 plays an important role in assembly of kinetochores by counteracting RNF41-mediated SGT1 (show SUGT1 Proteins) degradation. (PHLPP1 = PH domain and leucine rich repeat protein phosphatase 1; RNF41 = ring finger protein 41; SGT1 (show SUGT1 Proteins) = suppressor of G2 allele of SKP1 (show SUGT1 Proteins))

  5. Results show low expression level of NRDP1 in colorectal neoplasm independently of tumor stage.

  6. findings suggest that HBx promotes the progression of hepatocellular carcinoma by decreasing the stability of Nrdp1, which results in up-regulation of ErbB3 (show ERBB3 Proteins)

  7. the association between RNF41 polymorphisms and congenital heart disease in the Chinese Mongolian population

  8. Nrdp1S is a tumour suppressor that which potentiates the Nrdp1-mediated ubiquitination and degradation of ErbB3 (show ERBB3 Proteins). An Nrdp1S deficiency may also be an important factor in the loss of Nrdp1.

  9. HPV 16 E2 can modulate ErbB-3 (show ERBB3 Proteins) by interacting with Nrdp-1, which is involved in the regulation of this receptor, via ubiquitination and degradation.

  10. The results of this study suggested that Nrdp1-mediated ErbB3 (show ERBB3 Proteins) degradation suppresses glioma migration and invasion and that loss of Nrdp1 may amplify ErbB3 (show ERBB3 Proteins) signaling to contribute to glioma migration and invasion.

Mouse (Murine) Ring Finger Protein 41 (RNF41) interaction partners

  1. Data suggest that ring finger protein 41 Nrdp1 terminates T cell antigen receptors (TCRs) signaling by inactivating Zap70 (show ZAP70 Proteins) kinase.

  2. The novel Pdx1 (show PDX1 Proteins)-Clec16a-Nrdp1 pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes.

  3. demonstrate that Nrdp1-mediated ubiquitination and activation of C/EBPbeta (show CEBPB Proteins) contributes to a ubiquitin-dependent nonproteolytic pathway that up-regulates Arg1 (show ARG1 Proteins) expression and promotes M2 macrophage polarization

  4. Nrdp1 may be a key mediator in the development of cardiac dysfunction after DOX treatment and associated with inhibition of Akt (show AKT1 Proteins), ERK1/2 and STAT3 (show STAT3 Proteins).

  5. these results provide evidence for an important role for Nrdp1 in regulating ischemia/reperfusioninduced cardiac injury

  6. Post-transcriptional mechanisms contribute to the suppression of the ErbB3 (show ERBB3 Proteins) negative regulator protein Nrdp1 in mammary tumors.

  7. Rnf41 is nominated as a candidate gene for anxiety-like behaviors, depression, and vulnerability to seizures.

  8. Data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways.

Zebrafish Ring Finger Protein 41 (RNF41) interaction partners

  1. Nrdp1 is associated with differentiation process of the melanocyte lineage by regulating Erbb3b, an Erbb (show EGFR Proteins) signaling molecule along zebrafish embryogenesis.

RNF41 Protein Profile

Protein Summary

This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Ring Finger Protein 41 Proteins (RNF41)

  • ring finger protein 41 (RNF41)
  • ring finger protein 41 (Rnf41)
  • ring finger protein 41 (rnf41)
  • ring finger protein 41 S homeolog (rnf41.S)
  • ring finger protein 41, E3 ubiquitin protein ligase (RNF41)
  • 2210404G21Rik protein
  • 4930511A05Rik protein
  • 4933415P08Rik protein
  • D10Ertd722e protein
  • flrf protein
  • Nrdp1 protein
  • wu:fi13f07 protein
  • wu:fi25b06 protein
  • zgc:55389 protein

Protein level used designations for Ring Finger Protein 41 Proteins (RNF41)

E3 ubiquitin-protein ligase NRDP1 , fetal liver ring finger , neuregulin receptor degradation protein-1

426468 Gallus gallus
10193 Homo sapiens
67588 Mus musculus
362814 Rattus norvegicus
406837 Danio rerio
734308 Xenopus laevis
607044 Canis lupus familiaris
614134 Bos taurus
100173246 Pongo abelii
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