S100 Calcium Binding Protein A6 (S100A6) ELISA Kits

Human S100 Calcium Binding Protein A6 (S100A6) interaction partners

1. REVIEW: cellular function of S100A6 and its ligands, CacyBP/SIP and Sgt1

2. The expression MMP-9 and S100A6 in the tear film decreased in keratoconus patients after corneal collagen crosslinking.

3. Report alterations in the expression of cannabinoid receptors, apelin and S100A6 in the hearts of women over 50.

4. findings suggest that the S100A6 gene may be involved in the pathogenesis of endometriosis, since they participate in mechanisms such as inhibition of apoptosis, angiogenesis and cell proliferation, which lead to the loss of cell homeostasis in the ectopic endometrium, thus contributing to the implantation and survival of the tissue in the extrauterine environment.

5. Together, the data presented here indicate a close interaction between ageing and sex on the distribution and levels of cannabinoid receptors (CB1, CB2), S100A6 and CacyBP/SIP in the human heart.

6. aberrant S100A16 expression might be modulated by its DNA hypomethylation and serves as an independent prognostic indicator of unfavorable overall survival and recurrence-free survival in non-small cell lung adenocarcinoma

7. High expression of S100A6 in ICC defines a special group of patients with worse clinical characteristics and outcomes. Besides, S100A6 may promote ICC proliferation via activating p38/MAPK pathway.

8. The results suggest that binding of S100A6 to integrin beta1 affects cell adhesion/proliferation due to activation of ILK and FAK signaling pathways.

9. Authors demonstrated that the expression of S100A6 was significantly associated with patient age and tumor differentiation.

10. Data show that S100 calcium binding protein A6 (S100A6) is required for the Ca2+-dependent nuclear translocation of calcyclin binding protein (CacyBP/SIP) in colon cancer SW480 cells.

11. Isothermal titration calorimetry measured the binding of peptides with diverse sequence and biochemistry to human S100A5 and S110A6. These proteins bound distinct, but overlapping, sets of peptide targets. The specificity of S100 peptide interfaces is likely important for the biology of these proteins.

12. S100A6 is a potential risk marker for screening of cholangiocarcinoma.

13. The S100A6 interacts with FOR20 and related centrosomal proteins through a conserved N-terminal domain, suggesting a novel Ca(2+)-dependent regulation of centrosomal function.

14. REVIEW: summary of novel discoveries concerning S100A6 targets, its involvement in cellular signaling pathways, and presence in stem/progenitor cells, extracellular matrix and body fluids of diseased patients

15. Results showed that S100A6 was markedly up-regulated in nasopharyngeal carcinoma (NPC) tissues and cell lines and, may promote NPC development via the activation of p38/MAPK signaling pathways.

16. As an intracellular protein, S100A6 has been implicated in the regulation of several cellular functions, such as proliferation, apoptosis, the cytoskeleton dynamics, and the cellular response to different stress factors. S100A6 can be secreted/released by certain cell types which points to extracellular effects of the protein. [review]

17. suppression of S100A6 expression with RNAi significantly decreased the expression levels of beta-catenin, inhibited the growth and migration of eutopic endometrial stromal cells, and promoted their apoptosis.

18. Study reports the crystallographic structure of an S100-bound full-length RAGE ectodomain. The structure reveals a unique dimeric conformation of RAGE, which appears suited for signal transduction, and shows that the S100A6 protein adopts a non-canonical homodimeric arrangement.

19. STAT1 suppression by S100A6 may represent a promising therapeutic target to facilitate reendothelialization in damaged vessels.

20. Our results indicate that serum levels of S100A2 and S100A6 are significantly elevated in early stage non-small cell lung cancer

Pig (Porcine) S100 Calcium Binding Protein A6 (S100A6) interaction partners

1. S100A6 is upregulated during PRRSV infection; there is a putative NF-kappaB binding site in the core promoter region

Mouse (Murine) S100 Calcium Binding Protein A6 (S100A6) interaction partners

1. our data provide the first evidence that S100A6 is a specific marker of neural stem cells and astrocyte precursors

2. new insight into the interaction between S100 proteins and CacyBP/SIP

3. the S100A6 protein is involved in multiple aspects of fibroblast physiology and that its presence ensures normal fibroblast proliferation and function

4. S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients

5. calcyclin has a role as an accessory protein involved in the cation-sensing pathway in osteoblasts

6. Calcyclin is one of the candidate proteins that plays a role in osteoblastogenesis in response to simvastatin, although the precise functions of calcyclin in osteoblast remain to be verified.

7. calcyclin gene expression was analyzed at three different stages in differentiating MyoD(-)C2C12 myoblasts

8. Annexin XI and calcyclin colocalize in proliferating cells of the embryonic mouse testis

9. S100A2 and S100A6 interact with another TPR protein Tom70 and regulate the Tom70-ligand interaction in vitro

10. preferentially expressed in mouse model of allergen-induced airway inflammation and remodeling

11. enhancement of S100A6 expression plays an important role in MLL-AF4-associated leukemogenesis